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1977 1
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1994 5
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2000 3
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2007 8
2008 11
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2010 6
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220 results

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Page 1
Mitotic ER-mitochondria contact enhances mitochondrial Ca(2+) influx to promote cell division.
Zhao G, Jia M, Zhu S, Ren H, Wang G, Xin G, Sun M, Wang X, Lin Q, Jiang Q, Zhang C. Zhao G, et al. Cell Rep. 2024 Oct 22;43(10):114794. doi: 10.1016/j.celrep.2024.114794. Epub 2024 Sep 28. Cell Rep. 2024. PMID: 39342616 Free article.
Cell division is tightly regulated and requires an expanded energy supply. However, how this energy is generated remains unclear. ...Depletion of LBR disrupts the Ca(2+) influx surge, reduces ATP production, and postpones the metaphase-anaphase transition …
Cell division is tightly regulated and requires an expanded energy supply. However, how this energy is generated remains unclear. ... …
An intrinsic S/G2 checkpoint enforced by ATR.
Saldivar JC, Hamperl S, Bocek MJ, Chung M, Bass TE, Cisneros-Soberanis F, Samejima K, Xie L, Paulson JR, Earnshaw WC, Cortez D, Meyer T, Cimprich KA. Saldivar JC, et al. Science. 2018 Aug 24;361(6404):806-810. doi: 10.1126/science.aap9346. Science. 2018. PMID: 30139873 Free PMC article.
The cell cycle is strictly ordered to ensure faithful genome duplication and chromosome segregation. Control mechanisms establish this order by dictating when a cell transitions from one phase to the next. Much is known about the control of the G(1)/S, …
The cell cycle is strictly ordered to ensure faithful genome duplication and chromosome segregation. Control mechanisms establ …
Cell cycle-regulated proteolysis of mitotic target proteins.
Bastians H, Topper LM, Gorbsky GL, Ruderman JV. Bastians H, et al. Mol Biol Cell. 1999 Nov;10(11):3927-41. doi: 10.1091/mbc.10.11.3927. Mol Biol Cell. 1999. PMID: 10564281 Free PMC article.
The ubiquitin-dependent proteolysis of mitotic cyclin B, which is catalyzed by the anaphase-promoting complex/cyclosome (APC/C) and ubiquitin-conjugating enzyme H10 (UbcH10), begins around the time of the metaphase-anaphase transition and continues thr …
The ubiquitin-dependent proteolysis of mitotic cyclin B, which is catalyzed by the anaphase-promoting complex/cyclosome (APC/C) and u …
Mitotic regulation of the anaphase-promoting complex.
Baker DJ, Dawlaty MM, Galardy P, van Deursen JM. Baker DJ, et al. Cell Mol Life Sci. 2007 Mar;64(5):589-600. doi: 10.1007/s00018-007-6443-1. Cell Mol Life Sci. 2007. PMID: 17334950 Free PMC article. Review.
The well-established view is that Cdc20 activates APC/C from the onset of mitosis through the metaphase-anaphase transition, and that Cdh1 does so from anaphase through G1. Recent work, however, indicates that Cdh1 also activates APC/C in early mitosis and th …
The well-established view is that Cdc20 activates APC/C from the onset of mitosis through the metaphase-anaphase transition …
Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition.
Yuan K, O'Farrell PH. Yuan K, et al. Curr Biol. 2015 Mar 16;25(6):811-816. doi: 10.1016/j.cub.2015.01.053. Epub 2015 Mar 5. Curr Biol. 2015. PMID: 25754637 Free PMC article.
The timing mechanism for mitotic progression is still poorly understood. The spindle assembly checkpoint (SAC), whose reversal upon chromosome alignment is thought to time anaphase [1-3], is functional during the rapid mitotic cycles of the Drosophila embryo; but it …
The timing mechanism for mitotic progression is still poorly understood. The spindle assembly checkpoint (SAC), whose reversal upon c …
A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores.
Stewart MG, Carrier JS, Zahm JA, Harrison SC, Miller MP. Stewart MG, et al. J Cell Biol. 2025 Aug 4;224(8):e202410196. doi: 10.1083/jcb.202410196. Epub 2025 Jun 27. J Cell Biol. 2025. PMID: 40576560 Free PMC article.
Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determines a redistribution from kinetochores to spindle microtubules. ...Blocking Stu2T866 phosphorylation disrupts anaphase spindle progression, a …
Regulation of the XMAP215 family member and microtubule polymerase, Stu2, at the metaphase-anaphase transition determin …
Regulation of cAMP on the first mitotic cell cycle of mouse embryos.
Yu A, Zhang Z, Bi Q, Sun B, Su W, Guan Y, Mu R, Miao C, Zhang J, Yu B. Yu A, et al. Mol Reprod Dev. 2008 Mar;75(3):489-95. doi: 10.1002/mrd.20782. Mol Reprod Dev. 2008. PMID: 18022836
Here, we demonstrated that following activation of MPF, MAPK activity was steady, whereas Plk1 activity fluctuated during the first cell cycle. Plk1 activity was the highest at metaphase and decreased at metaphase-anaphase transition. ...Above a …
Here, we demonstrated that following activation of MPF, MAPK activity was steady, whereas Plk1 activity fluctuated during the first cell …
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.
Goto H, Kiyono T, Tomono Y, Kawajiri A, Urano T, Furukawa K, Nigg EA, Inagaki M. Goto H, et al. Nat Cell Biol. 2006 Feb;8(2):180-7. doi: 10.1038/ncb1350. Epub 2005 Dec 25. Nat Cell Biol. 2006. PMID: 16378098
Mitotic chromosomal dynamics is regulated by the coordinated activities of many mitotic kinases, such as cyclin-dependent kinase 1 (Cdk1), Aurora-B or Polo-like kinase 1 (Plk1), but the mechanisms of their coordination remain unknown. ...
Mitotic chromosomal dynamics is regulated by the coordinated activities of many mitotic kinases, such as cyclin-dependent kina …
Control of metaphase-anaphase progression by proteolysis: cyclosome function regulated by the protein kinase A pathway, ubiquitination and localization.
Yanagida M, Yamashita YM, Tatebe H, Ishii K, Kumada K, Nakaseko Y. Yanagida M, et al. Philos Trans R Soc Lond B Biol Sci. 1999 Sep 29;354(1389):1559-69; discussion 1569-70. doi: 10.1098/rstb.1999.0499. Philos Trans R Soc Lond B Biol Sci. 1999. PMID: 10582241 Free PMC article. Review.
Ubiquitin-mediated proteolysis is fundamental to cell cycle progression. In the fission yeast Schizosaccharomyces pombe, a mitotic cyclin (Cdc13), a key cell cycle regulator, is degraded for exiting mitosis, while Cut2 has to be destroyed for th …
Ubiquitin-mediated proteolysis is fundamental to cell cycle progression. In the fission yeast Schizosaccharomyces pombe, a …
Intracellular calcium mobilization regulates the activity of 26 S proteasome during the metaphase-anaphase transition in the ascidian meiotic cell cycle.
Kawahara H, Yokosawa H. Kawahara H, et al. Dev Biol. 1994 Dec;166(2):623-33. doi: 10.1006/dbio.1994.1342. Dev Biol. 1994. PMID: 7813781
During the metaphase-anaphase transition triggered by treatment with calcium ionophore, the activity of 26 S proteasome was found to be enhanced transiently and then decreased. ...The immunoblot analyses also indicated an inverse relation between the level of …
During the metaphase-anaphase transition triggered by treatment with calcium ionophore, the activity of 26 S proteasome …
220 results