Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1971 1
1972 1
1977 1
1979 1
1980 1
1985 1
1987 1
1988 2
1991 2
1992 4
1993 2
1994 3
1995 5
1996 4
1997 4
1998 3
1999 5
2000 5
2001 1
2002 2
2003 4
2005 1
2006 3
2007 2
2008 2
2009 2
2010 1
2012 1
2013 1
2014 1
2015 1
2016 6
2018 7
2019 6
2020 1
Text availability
Article attribute
Article type
Publication date

Search Results

87 results
Results by year
Filters applied: . Clear all
Page 1
Showing results for metase
Search for metasee instead (1 results)
METase/lncRNA HULC/FoxM1 reduced cisplatin resistance in gastric cancer by suppressing autophagy.
Xin L, Zhou Q, Yuan YW, Zhou LQ, Liu L, Li SH, Liu C. Xin L, et al. J Cancer Res Clin Oncol. 2019 Oct;145(10):2507-2517. doi: 10.1007/s00432-019-03015-w. Epub 2019 Sep 4. J Cancer Res Clin Oncol. 2019. PMID: 31485766
However, the underlying mechanism of methioninase (METase) in the regulation of autophagy and CDDP resistance of gastric cancer cells is still not clear. ...RESULTS: Lentiviral vector carrying METase (LV-METase) suppressed autophagy and CDDP resistance of dru …
However, the underlying mechanism of methioninase (METase) in the regulation of autophagy and CDDP resistance of gastric cancer cells …
Evaluation of METase-pemetrexed-loaded PEG-PLGA nanoparticles modified with anti-CD133-scFV for treatment of gastric carcinoma.
Xin L, Zhang HT, Yang WF, Li YF, Liu C. Xin L, et al. Biosci Rep. 2018 Jan 30;38(1):BSR20171001. doi: 10.1042/BSR20171001. Print 2018 Feb 28. Biosci Rep. 2018. PMID: 29229675 Free PMC article.
The structure characterization and biological functions of METase-pemetrexed-loaded scFV-PEG-PLGA NPs (scFV-METase/pemetrexed-NPs) in vitro were investigated. Functional scFV-PEG-PLGA NPs or PEG-PLGA NPs present low cell cytoxicity in CD133+ SGC7901 cells. scFV-M
The structure characterization and biological functions of METase-pemetrexed-loaded scFV-PEG-PLGA NPs (scFV-METase/pemetrexed- …
METase promotes cell autophagy via promoting SNHG5 and suppressing miR-20a in gastric cancer.
Xin L, Zhou LQ, Liu L, Yuan YW, Zhang HT, Zeng F. Xin L, et al. Int J Biol Macromol. 2019 Feb 1;122:1046-1052. doi: 10.1016/j.ijbiomac.2018.09.051. Epub 2018 Sep 15. Int J Biol Macromol. 2019. PMID: 30227213
BACKGROUND: Gastric cancer (GC) severely threatens human life, and METase seemed to inhibit tumor growth. However, the potential mechanism underlying it is still unclear. ...Overexpressed METase significantly promoted cell autophagy, which was abolished by down-regu …
BACKGROUND: Gastric cancer (GC) severely threatens human life, and METase seemed to inhibit tumor growth. However, the potential mech …
A novel design of HA-coated nanoparticles co-encapsulating plasmid METase and 5-Fu shows enhanced application in targeting gastric cancer stem cells.
Yang W, Zhang H, Xin L. Yang W, et al. Biol Chem. 2018 Feb 23;399(3):293-303. doi: 10.1515/hsz-2017-0208. Biol Chem. 2018. PMID: 29016350
Methioninase (METase)/5-Fu co-encaspulated NPs showed highest ζ size and lowest ζ potential than other NPs. The migration and tumorsphere formation ability of CD44(+) was stronger than CD44(-). ...It was concluded that HA-coated NPs enhance the target ability, while MET
Methioninase (METase)/5-Fu co-encaspulated NPs showed highest ζ size and lowest ζ potential than other NPs. The migration and tumorsp …
Hyaluronic acid-modified polyamidoamine dendrimer G5-entrapped gold nanoparticles delivering METase gene inhibits gastric tumor growth via targeting CD44+ gastric cancer cells.
Li YF, Zhang HT, Xin L. Li YF, et al. J Cancer Res Clin Oncol. 2018 Aug;144(8):1463-1473. doi: 10.1007/s00432-018-2678-5. Epub 2018 Jun 1. J Cancer Res Clin Oncol. 2018. PMID: 29858680
Nude mice xenograft models were used to evaluate the effect of HA-PAMAM-Au-METase on GC. RESULTS: The transfection of rMETase carried by HA-G5 PAMAM-Au visibly inhibited the proliferation and tumorsphere formation of GC cells through obviously enhancing METase activ …
Nude mice xenograft models were used to evaluate the effect of HA-PAMAM-Au-METase on GC. RESULTS: The transfection of rMETase carried …
Methioninase Gene Therapy.
Hoffman RM, Miki K, Al-Refaie W, Xu M, Tan Y. Hoffman RM, et al. Methods Mol Biol. 2019;1866:173-197. doi: 10.1007/978-1-4939-8796-2_14. Methods Mol Biol. 2019. PMID: 30725416
The combination of rAd-METase and rMETase was synergistic to kill these cells. Normal fibroblasts, on the other hand, appeared relatively resistant to the METase gene in the presence of rMETase. Adenoviral METase-transduced cancer cells were used in combinati …
The combination of rAd-METase and rMETase was synergistic to kill these cells. Normal fibroblasts, on the other hand, appeared relati …
Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells.
Thorpe M, Akula S, Hellman L. Thorpe M, et al. Dev Comp Immunol. 2016 Oct;63:84-95. doi: 10.1016/j.dci.2016.05.013. Epub 2016 May 20. Dev Comp Immunol. 2016. PMID: 27216028
A strict preference for Met in the P1 (cleavage) position, indicating metase specificity was observed. A screening of potential in vivo substrates was performed based on the derived P5-P3' consensus: Arg-Val-Thr-Gly-Met(↓)Ser-Leu-Val. ...
A strict preference for Met in the P1 (cleavage) position, indicating metase specificity was observed. A screening of potential in vi …
The mechanism study of lentiviral vector carrying methioninase enhances the sensitivity of drug-resistant gastric cancer cells to Cisplatin.
Xin L, Yang WF, Zhang HT, Li YF, Liu C. Xin L, et al. Br J Cancer. 2018 May;118(9):1189-1199. doi: 10.1038/s41416-018-0043-8. Epub 2018 Mar 26. Br J Cancer. 2018. PMID: 29576621 Free PMC article.
The influence of LV-METase transfection on cell viability and pathway-related proteins were assessed by MTT method and western blot, respectively. ...CONCLUSIONS: Our results suggest that LV-METase has potential as a therapeutic agent for gastric cancer treatment... …
The influence of LV-METase transfection on cell viability and pathway-related proteins were assessed by MTT method and western blot, …
Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine gamma-lyase conjugated with polyethylene glycol as an antitumor agent.
Takakura T, Takimoto A, Notsu Y, Yoshida H, Ito T, Nagatome H, Ohno M, Kobayashi Y, Yoshioka T, Inagaki K, Yagi S, Hoffman RM, Esaki N. Takakura T, et al. Cancer Res. 2006 Mar 1;66(5):2807-14. doi: 10.1158/0008-5472.CAN-05-3910. Cancer Res. 2006. PMID: 16510603 Free article.
Pegylated METase (PEG-METase), which contains pyridoxal 5'-phosphate (PLP) as a cofactor in the molecule, is a potent anticancer agent that can deplete L-methionine from plasma. ...We concluded that PLP was released from PEG-METase by serum albumin in vivo an …
Pegylated METase (PEG-METase), which contains pyridoxal 5'-phosphate (PLP) as a cofactor in the molecule, is a potent anticanc …
Modulation of human DNA methyltransferase activity and mRNA levels in the monoblast cell line U937 induced to differentiate with dibutyryl cyclic AMP and phorbol ester.
Soultanas P, Andrews PD, Burton DR, Hornby DP. Soultanas P, et al. J Mol Endocrinol. 1993 Oct;11(2):191-200. doi: 10.1677/jme.0.0110191. J Mol Endocrinol. 1993. PMID: 8297475
Equally, no DNA MeTase activity was detectable in nuclear extracts of fresh peripheral blood monocytes. Using both a U937 DNA MeTase cDNA and a mouse DNA MeTase cDNA as probes, steady-state levels of DNA MeTase mRNA were found to decline sharply betwee …
Equally, no DNA MeTase activity was detectable in nuclear extracts of fresh peripheral blood monocytes. Using both a U937 DNA MeTa
87 results
Jump to page
Feedback