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Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering.
Huber B, Borchers K, Tovar GE, Kluger PJ. Huber B, et al. J Biomater Appl. 2016 Jan;30(6):699-710. doi: 10.1177/0885328215587450. Epub 2015 May 27. J Biomater Appl. 2016. PMID: 26017717
In this study, we evaluated the suitability of photo-crosslinkable methacrylated gelatin (GM) and mature adipocytes as components for the composition of three-dimensional fatty tissue constructs. ...This work demonstrates that mature adipocyt
In this study, we evaluated the suitability of photo-crosslinkable methacrylated gelatin (GM) and mature adipocytes
Methacrylated gelatin/hyaluronan-based hydrogels for soft tissue engineering.
Kessler L, Gehrke S, Winnefeld M, Huber B, Hoch E, Walter T, Wyrwa R, Schnabelrauch M, Schmidt M, Kückelhaus M, Lehnhardt M, Hirsch T, Jacobsen F. Kessler L, et al. J Tissue Eng. 2017 Dec 21;8:2041731417744157. doi: 10.1177/2041731417744157. eCollection 2017 Jan-Dec. J Tissue Eng. 2017. PMID: 29318000 Free PMC article.
In vitro-generated soft tissue could provide alternate therapies for soft tissue defects. The aim of this study was to evaluate methacrylated gelatin/hyaluronan as scaffolds for soft tissue engineering and their interaction with human adipose-derived stem cells (hAS …
In vitro-generated soft tissue could provide alternate therapies for soft tissue defects. The aim of this study was to evaluate methacryl
Bioprinting predifferentiated adipose-derived mesenchymal stem cell spheroids with methacrylated gelatin ink for adipose tissue engineering.
Colle J, Blondeel P, De Bruyne A, Bochar S, Tytgat L, Vercruysse C, Van Vlierberghe S, Dubruel P, Declercq H. Colle J, et al. J Mater Sci Mater Med. 2020 Mar 23;31(4):36. doi: 10.1007/s10856-020-06374-w. J Mater Sci Mater Med. 2020. PMID: 32206922
A scaffold was bioprinted using encapsulated ASC spheroids in methacrylated gelatin ink (GelMA). Uniform ASC spheroids with an ideal geometry and diameter for bioprinting were formed, using a high-throughput non-adhesive agarose microwell system. ...Viable spheroids …
A scaffold was bioprinted using encapsulated ASC spheroids in methacrylated gelatin ink (GelMA). Uniform ASC spheroids with an …
Decellularized fennel and dill leaves as possible 3D channel network in GelMA for the development of an in vitro adipose tissue model.
Grilli F, Pitton M, Altomare L, Farè S. Grilli F, et al. Front Bioeng Biotechnol. 2022 Oct 31;10:984805. doi: 10.3389/fbioe.2022.984805. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 36394006 Free PMC article.
In particular, in order to obtain an adipose matrix capable of mimicking the composition of the adipose tissue, methacrylated gelatin (GelMA), UV photo-crosslinkable, was selected. ...No cytotoxic effects were detected comparing the three prepared GelMA/D-leaf struc …
In particular, in order to obtain an adipose matrix capable of mimicking the composition of the adipose tissue, methacrylated gela
Stromal cell-laden 3D hydrogel microwell arrays as tumor microenvironment model for studying stiffness dependent stromal cell-cancer interactions.
Yue X, Nguyen TD, Zellmer V, Zhang S, Zorlutuna P. Yue X, et al. Biomaterials. 2018 Jul;170:37-48. doi: 10.1016/j.biomaterials.2018.04.001. Epub 2018 Apr 3. Biomaterials. 2018. PMID: 29653286
Our results showed that, tumor spheroids closely interacted with the pre-adipocyte stromal cells encapsulated within the microwell array, influencing their differentiation and maturation degree in a stiffness related manner. ...
Our results showed that, tumor spheroids closely interacted with the pre-adipocyte stromal cells encapsulated within the microwell ar …