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Methacrylated gelatin and mature adipocytes are promising components for adipose tissue engineering.
Huber B, Borchers K, Tovar GE, Kluger PJ. Huber B, et al. J Biomater Appl. 2016 Jan;30(6):699-710. doi: 10.1177/0885328215587450. Epub 2015 May 27. J Biomater Appl. 2016. PMID: 26017717
In this study, we evaluated the suitability of photo-crosslinkable methacrylated gelatin (GM) and mature adipocytes as components for the composition of three-dimensional fatty tissue constructs. ...This work demonstrates that mature adipocyt
In this study, we evaluated the suitability of photo-crosslinkable methacrylated gelatin (GM) and mature adipocytes
Methacrylated gelatin/hyaluronan-based hydrogels for soft tissue engineering.
Kessler L, Gehrke S, Winnefeld M, Huber B, Hoch E, Walter T, Wyrwa R, Schnabelrauch M, Schmidt M, Kückelhaus M, Lehnhardt M, Hirsch T, Jacobsen F. Kessler L, et al. J Tissue Eng. 2017 Dec 21;8:2041731417744157. doi: 10.1177/2041731417744157. eCollection 2017 Jan-Dec. J Tissue Eng. 2017. PMID: 29318000 Free PMC article.
The aim of this study was to evaluate methacrylated gelatin/hyaluronan as scaffolds for soft tissue engineering and their interaction with human adipose-derived stem cells (hASCs). ...By induction of adipogenic differentiation, the mature adipocytes we …
The aim of this study was to evaluate methacrylated gelatin/hyaluronan as scaffolds for soft tissue engineering and their inte …
Decellularized fennel and dill leaves as possible 3D channel network in GelMA for the development of an in vitro adipose tissue model.
Grilli F, Pitton M, Altomare L, Farè S. Grilli F, et al. Front Bioeng Biotechnol. 2022 Oct 31;10:984805. doi: 10.3389/fbioe.2022.984805. eCollection 2022. Front Bioeng Biotechnol. 2022. PMID: 36394006 Free PMC article.
In particular, in order to obtain an adipose matrix capable of mimicking the composition of the adipose tissue, methacrylated gelatin (GelMA), UV photo-crosslinkable, was selected. Decellularized fennel, wild fennel and, dill leaves have been incorporated into the G …
In particular, in order to obtain an adipose matrix capable of mimicking the composition of the adipose tissue, methacrylated gela
Visible light photo-crosslinking of biomimetic gelatin-hyaluronic acid hydrogels for adipose tissue engineering.
Pitton M, Urzì C, Farè S, Contessi Negrini N. Pitton M, et al. J Mech Behav Biomed Mater. 2024 Oct;158:106675. doi: 10.1016/j.jmbbm.2024.106675. Epub 2024 Jul 25. J Mech Behav Biomed Mater. 2024. PMID: 39068848 Free article.
However, the challenge in developing 3D constructs of AT resides in designing artificial matrices that can mimic the structural properties of native AT and support adipocytes biological functions. Herein, we developed photocrosslinkable hydrogels by employing gelatin
However, the challenge in developing 3D constructs of AT resides in designing artificial matrices that can mimic the structural properties o …
Bioprinting predifferentiated adipose-derived mesenchymal stem cell spheroids with methacrylated gelatin ink for adipose tissue engineering.
Colle J, Blondeel P, De Bruyne A, Bochar S, Tytgat L, Vercruysse C, Van Vlierberghe S, Dubruel P, Declercq H. Colle J, et al. J Mater Sci Mater Med. 2020 Mar 23;31(4):36. doi: 10.1007/s10856-020-06374-w. J Mater Sci Mater Med. 2020. PMID: 32206922
A scaffold was bioprinted using encapsulated ASC spheroids in methacrylated gelatin ink (GelMA). Uniform ASC spheroids with an ideal geometry and diameter for bioprinting were formed, using a high-throughput non-adhesive agarose microwell system. ...Viable spheroids …
A scaffold was bioprinted using encapsulated ASC spheroids in methacrylated gelatin ink (GelMA). Uniform ASC spheroids with an …
Stromal cell-laden 3D hydrogel microwell arrays as tumor microenvironment model for studying stiffness dependent stromal cell-cancer interactions.
Yue X, Nguyen TD, Zellmer V, Zhang S, Zorlutuna P. Yue X, et al. Biomaterials. 2018 Jul;170:37-48. doi: 10.1016/j.biomaterials.2018.04.001. Epub 2018 Apr 3. Biomaterials. 2018. PMID: 29653286
Our results showed that, tumor spheroids closely interacted with the pre-adipocyte stromal cells encapsulated within the microwell array, influencing their differentiation and maturation degree in a stiffness related manner. ...
Our results showed that, tumor spheroids closely interacted with the pre-adipocyte stromal cells encapsulated within the microwell ar …
Optimized Adipogenic Differentiation and Delivery of Bovine Umbilical Cord Stem Cells for Cultivated Meat.
Ozhava D, Lee K, Bektas C, Jackson A, Patel K, Mao Y. Ozhava D, et al. Gels. 2024 Jul 24;10(8):488. doi: 10.3390/gels10080488. Gels. 2024. PMID: 39195017 Free PMC article.
Cultivated meat, also known as cell-based or clean meat, utilizes mesenchymal stem cells to cultivate mature cell types like adipocytes, which are pivotal for imparting the desired taste and texture. ...In this study, we investigated the adipogenic differentiation p …
Cultivated meat, also known as cell-based or clean meat, utilizes mesenchymal stem cells to cultivate mature cell types like adipo