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Page 1
Breath methane concentrations and markers of obesity in patients with functional gastrointestinal disorders.
Wilder-Smith CH, Olesen SS, Materna A, Drewes AM. Wilder-Smith CH, et al. United European Gastroenterol J. 2018 May;6(4):595-603. doi: 10.1177/2050640617744457. Epub 2017 Nov 15. United European Gastroenterol J. 2018. PMID: 29881615 Free PMC article.
BACKGROUND: Obesity is associated with changes in the intestinal microbiome and methane-producing archaea may be involved in energy homeostasis. OBJECTIVE: The objective of this article is to investigate the associations between intestinal methane prod …
BACKGROUND: Obesity is associated with changes in the intestinal microbiome and methane-producing archaea may be involv …
Bacteroides, Metabolites, and Lymphocytes: A Triad of Biomarkers in Small Intestinal Bacterial Overgrowth.
Wang Z, Tan W, Wu L, Zhang P, Xiong H, Zhu L, Huang J, Cui J, Li L, Guo C, He L, Wei H, Liu H. Wang Z, et al. Food Sci Nutr. 2025 Jun 20;13(6):e70367. doi: 10.1002/fsn3.70367. eCollection 2025 Jun. Food Sci Nutr. 2025. PMID: 40548188 Free PMC article.
Stool samples from 29 patients underwent 16S rRNA sequencing to analyze gut microbiota and metabolites. Then we explored links between microbiota, metabolites, symptoms, and serum markers. 405 persons in all completed the hydrogen methane breath test, of whom …
Stool samples from 29 patients underwent 16S rRNA sequencing to analyze gut microbiota and metabolites. Then we explored links betwee …
Association between breath methane concentration and visceral fat area: a population-based cross-sectional study.
Ozato N, Saito S, Yamaguchi T, Katashima M, Tokuda I, Sawada K, Katsuragi Y, Kakuta M, Imoto S, Ihara K, Nakaji S. Ozato N, et al. J Breath Res. 2020 Feb 25;14(2):026008. doi: 10.1088/1752-7163/ab61c6. J Breath Res. 2020. PMID: 31835267
However, these studies define obesity using BMI, not VFA. In this population-based cross-sectional study, we investigated the relationship between breath gases (methane and hydrogen) and both VFA and BMI. ...The Methanogen + group was further divided i …
However, these studies define obesity using BMI, not VFA. In this population-based cross-sectional study, we investigated the …
Influence of Body Composition and Specific Anthropometric Parameters on SIBO Type.
Wielgosz-Grochowska JP, Domanski N, Drywień ME. Wielgosz-Grochowska JP, et al. Nutrients. 2023 Sep 18;15(18):4035. doi: 10.3390/nu15184035. Nutrients. 2023. PMID: 37764818 Free PMC article.
Recent observations have shown that Small Intestinal Bacterial Overgrowth (SIBO)affects the host through various mechanisms. While both weight loss and obesity have been reported in the SIBO population due to alterations in the gut microbiome, very little is known a …
Recent observations have shown that Small Intestinal Bacterial Overgrowth (SIBO)affects the host through various mechanisms. While both weig …
Intestinal methane production in obese individuals is associated with a higher body mass index.
Basseri RJ, Basseri B, Pimentel M, Chong K, Youdim A, Low K, Hwang L, Soffer E, Chang C, Mathur R. Basseri RJ, et al. Gastroenterol Hepatol (N Y). 2012 Jan;8(1):22-8. Gastroenterol Hepatol (N Y). 2012. PMID: 22347829 Free PMC article.
BACKGROUND: Obesity is an epidemic that affects 1 in 3 individuals in the United States, and recent evidence suggests that enteric microbiota may play a significant role in the development of obesity. ...BMI was significantly higher in methane-p …
BACKGROUND: Obesity is an epidemic that affects 1 in 3 individuals in the United States, and recent evidence suggests that enteric …
Intestinal methane production is associated with decreased weight loss following bariatric surgery.
Mathur R, Mundi MS, Chua KS, Lorentz PA, Barlow GM, Lin E, Burch M, Youdim A, Pimentel M. Mathur R, et al. Obes Res Clin Pract. 2016 Nov-Dec;10(6):728-733. doi: 10.1016/j.orcp.2016.06.006. Epub 2016 Jul 2. Obes Res Clin Pract. 2016. PMID: 27380731
To determine whether methane and hydrogen on breath test affects weight loss after bariatric surgery, 156 subjects (pre-surgery BMI 33) were recruited 4 months after surgery. Pre- and post-surgery weights and BMIs were recorded. Post-surgery methane and hyd …
To determine whether methane and hydrogen on breath test affects weight loss after bariatric surgery, 156 subjects (pre-surgery BM
Syntrophy via Interspecies H2 Transfer between Christensenella and Methanobrevibacter Underlies Their Global Cooccurrence in the Human Gut.
Ruaud A, Esquivel-Elizondo S, de la Cuesta-Zuluaga J, Waters JL, Angenent LT, Youngblut ND, Ley RE. Ruaud A, et al. mBio. 2020 Feb 4;11(1):e03235-19. doi: 10.1128/mBio.03235-19. mBio. 2020. PMID: 32019803 Free PMC article.
Across human populations, 16S rRNA gene-based surveys of gut microbiomes have revealed that the bacterial family Christensenellaceae and the archaeal family Methanobacteriaceae cooccur and are enriched in individuals with a lean, compared to an obese, body mass inde …
Across human populations, 16S rRNA gene-based surveys of gut microbiomes have revealed that the bacterial family Christensenellaceae …
Integrative and quantitative bioenergetics: Design of a study to assess the impact of the gut microbiome on host energy balance.
Corbin KD, Krajmalnik-Brown R, Carnero EA, Bock C, Emerson R, Rittmann BE, Marcus AK, Davis T, Dirks B, Ilhan ZE, Champagne C, Smith SR. Corbin KD, et al. Contemp Clin Trials Commun. 2020 Aug 19;19:100646. doi: 10.1016/j.conctc.2020.100646. eCollection 2020 Sep. Contemp Clin Trials Commun. 2020. PMID: 32875141 Free PMC article.
The literature is replete with clinical studies that characterize the structure, diversity, and function of the gut microbiome and correlate the results to different disease states, including obesity. Whether the microbiome has a direct impact on obesity
The literature is replete with clinical studies that characterize the structure, diversity, and function of the gut microbiome and co …
Epigenetic and microbiome responses to greens supplementation in obese older adults: results from a randomized crossover-controlled trial.
Robinson LA, Cavanah AM, Lennon S, Mattingly ML, Pol WV, Huggins KW, Greene MW, Roberts MD, Frugé AD. Robinson LA, et al. Front Nutr. 2026 Feb 4;13:1750030. doi: 10.3389/fnut.2026.1750030. eCollection 2026. Front Nutr. 2026. PMID: 41717034 Free PMC article.
Secondary measures included clinical metabolic biomarkers, microbiome diversity, breath hydrogen and methane, body composition, actigraphy, dietary intake, and quality of life questionnaires [RAND 12 item short form questionnaire (SF-12), and 21-item Depression, Anx …
Secondary measures included clinical metabolic biomarkers, microbiome diversity, breath hydrogen and methane, body composition …
Alterations of the Gut Microbiome Associated to Methane Metabolism in Mexican Children with Obesity.
Murga-Garrido SM, Orbe-Orihuela YC, Díaz-Benítez CE, Castañeda-Márquez AC, Cornejo-Granados F, Ochoa-Leyva A, Sanchez-Flores A, Cruz M, Burguete-García AI, Lagunas-Martínez A. Murga-Garrido SM, et al. Children (Basel). 2022 Jan 24;9(2):148. doi: 10.3390/children9020148. Children (Basel). 2022. PMID: 35204867 Free PMC article.
Gut microbiota is associated with the development of metabolic disorders. To study its association with childhood obesity, we performed a cross-sectional study with 46 children (6-12 years old). ...We classified each participant into normal weight (NW) or overweight …
Gut microbiota is associated with the development of metabolic disorders. To study its association with childhood obesity, we …