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Table representation of search results timeline featuring number of search results per year.

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1955 1
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1975 13
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1978 3
1979 4
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1983 13
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1985 16
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1988 12
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1990 12
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1999 67
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2002 72
2003 66
2004 68
2005 76
2006 57
2007 66
2008 82
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2010 65
2011 68
2012 70
2013 80
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2,029 results

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Page 1
B-vitamins, homocysteine metabolism and CVD.
Strain JJ, Dowey L, Ward M, Pentieva K, McNulty H. Strain JJ, et al. Proc Nutr Soc. 2004 Nov;63(4):597-603. doi: 10.1079/pns2004390. Proc Nutr Soc. 2004. PMID: 15831132 Review.
The present review focuses on the B-vitamins, i.e. folate, vitamin B12, vitamin B6 and riboflavin, that are involved in homocysteine metabolism. ...Vitamin B12 and, to a lesser extent, vitamin B6 are also effective at lowering plasma homocysteine, espe …
The present review focuses on the B-vitamins, i.e. folate, vitamin B12, vitamin B6 and riboflavin, that are involved in hom …
Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks.
Raghubeer S, Matsha TE. Raghubeer S, et al. Nutrients. 2021 Dec 20;13(12):4562. doi: 10.3390/nu13124562. Nutrients. 2021. PMID: 34960114 Free PMC article. Review.
The 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme is vital for cellular homeostasis due to its key functions in the one-carbon cycle, which include methionine and folate metabolism and protein, DNA, and RNA synthesis. The enzyme is responsible for maintaining …
The 5-10-methylenetetrahydrofolate reductase (MTHFR) enzyme is vital for cellular homeostasis due to its key functions in the one-carbon cyc …
Effects of B Vitamins on Homocysteine Lowering and Thrombotic Risk Reduction-A Review of Randomized Controlled Trials Published Since January 1996.
Li M, Ren R, Wang K, Wang S, Chow A, Yang AK, Lu Y, Leo C. Li M, et al. Nutrients. 2025 Mar 24;17(7):1122. doi: 10.3390/nu17071122. Nutrients. 2025. PMID: 40218880 Free PMC article. Review.
Homocysteine is an amino acid derived from methionine which is metabolized via vitamin B(6) (pyridoxine)- and vitamin B(12) (cobalamin)-dependent pathways. Supplementation of B vitamins has been shown to effectively reduce plasma homocysteine le …
Homocysteine is an amino acid derived from methionine which is metabolized via vitamin B(6) (pyridoxine)- and vitamin B(12) (c …
Homocysteine and B vitamins.
Cook S, Hess OM. Cook S, et al. Handb Exp Pharmacol. 2005;(170):325-38. doi: 10.1007/3-540-27661-0_11. Handb Exp Pharmacol. 2005. PMID: 16596805 Review.
Homocysteine (tHcy) is an intermediate sulfur-containing amino acid which acts as a methyl group donor for methionine metabolism. ...Homocystinuria, an infrequent genetic disease usually due to lack of cystathione beta-synthase, has been found with severely elevated …
Homocysteine (tHcy) is an intermediate sulfur-containing amino acid which acts as a methyl group donor for methionine metaboli …
B vitamins, homocysteine, and neurocognitive function in the elderly.
Selhub J, Bagley LC, Miller J, Rosenberg IH. Selhub J, et al. Am J Clin Nutr. 2000 Feb;71(2):614S-620S. doi: 10.1093/ajcn/71.2.614s. Am J Clin Nutr. 2000. PMID: 10681269 Review.
Evidence of the importance of the B vitamins folic acid, vitamin B-12, and vitamin B-6 for the well-being and normal function of the brain derives from data showing neurologic and psychologic dysfunction in vitamin deficiency states and in cases of congenital defect …
Evidence of the importance of the B vitamins folic acid, vitamin B-12, and vitamin B-6 for the well-being and normal function …
Medicines associated with folate-homocysteine-methionine pathway disruption.
Vidmar M, Grželj J, Mlinarič-Raščan I, Geršak K, Dolenc MS. Vidmar M, et al. Arch Toxicol. 2019 Feb;93(2):227-251. doi: 10.1007/s00204-018-2364-z. Epub 2018 Nov 29. Arch Toxicol. 2019. PMID: 30499019 Review.
It also acts in conjunction with cobalamin (vitamin B(12)) as a fundamental cofactor in the remethylation cycle that converts homocysteine to methionine. A deficiency in folate or vitamin B(12) can lead to elevated homocysteine level, which has been identifie …
It also acts in conjunction with cobalamin (vitamin B(12)) as a fundamental cofactor in the remethylation cycle that converts homocystein …
The role of B vitamins in stroke prevention.
Bjørklund G, Peana M, Dadar M, Lozynska I, Chirumbolo S, Lysiuk R, Lenchyk L, Upyr T, Severin B. Bjørklund G, et al. Crit Rev Food Sci Nutr. 2022;62(20):5462-5475. doi: 10.1080/10408398.2021.1885341. Epub 2021 Mar 16. Crit Rev Food Sci Nutr. 2022. PMID: 33724098 Review.
However, they are not completely in agreement about B vitamins' role, particularly folic acid levels, vitamin B(12), and B(6), in lowering the homocysteine concentrations in people at high stroke risk. A very complex relationship exists between Hcy and B …
However, they are not completely in agreement about B vitamins' role, particularly folic acid levels, vitamin B(12), and B(6), …
Homocystinuria: pathogenetic mechanisms.
Grieco AJ. Grieco AJ. Am J Med Sci. 1977 Mar-Apr;273(2):120-32. Am J Med Sci. 1977. PMID: 324277 Review.
Homocystinuria with elevated plasma homocysteine and methionine levels is the result of deficient activity of cystathionine synthetase, the enzyme catalyzing conversion of homocysteine to cystathionine. ...Low methionine homocystinuria, with deficient …
Homocystinuria with elevated plasma homocysteine and methionine levels is the result of deficient activity of cystathionine sy …
[Homocysteine metabolism].
Hashimoto T, Shinohara Y, Hasegawa H. Hashimoto T, et al. Yakugaku Zasshi. 2007 Oct;127(10):1579-92. doi: 10.1248/yakushi.127.1579. Yakugaku Zasshi. 2007. PMID: 17917419 Free article. Review. Japanese.
Homocysteine, a sulfur amino acid, is an intermediate metabolite of methionine. In 1969, McCully reported autopsy evidence of extensive arterial thrombosis and atherosclerosis in children with elevated plasma homocysteine concentrations and homocystinuria. .. …
Homocysteine, a sulfur amino acid, is an intermediate metabolite of methionine. In 1969, McCully reported autopsy evidence of …
B-vitamins, homocysteine and gene polymorphism in adults with fasting or post-methionine loading hyperhomocysteinemia.
Cheng CH, Huang YC, Chen FP, Chou MC, Tsai TP. Cheng CH, et al. Eur J Nutr. 2008 Dec;47(8):491-8. doi: 10.1007/s00394-008-0752-5. Epub 2008 Oct 31. Eur J Nutr. 2008. PMID: 18979127
BACKGROUND: Although fasting and post-methionine loading (PML) homocysteine concentrations are not necessarily related, a high percentage of hyperhomocysteinemia cases would be missed if methionine loading was not performed. AIM OF THE STUDY: The influences o …
BACKGROUND: Although fasting and post-methionine loading (PML) homocysteine concentrations are not necessarily related, a high …
2,029 results