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82 results

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Page 1
Methylene blue as an antimalarial agent.
Schirmer RH, Coulibaly B, Stich A, Scheiwein M, Merkle H, Eubel J, Becker K, Becher H, Müller O, Zich T, Schiek W, Kouyaté B. Schirmer RH, et al. Redox Rep. 2003;8(5):272-5. doi: 10.1179/135100003225002899. Redox Rep. 2003. PMID: 14962363 Free article. Review.
Methylene blue has intrinsic antimalarial activity and it can act as a chloroquine sensitizer. In addition, methylene blue must be considered for preventing methemoglobinemia, a serious complication of malarial anemia. ...
Methylene blue has intrinsic antimalarial activity and it can act as a chloroquine sensitizer. In addition, methylen …
Headache and Methemoglobinemia.
Khan FA, McIntyre C, Khan AM, Maslov A. Khan FA, et al. Headache. 2020 Jan;60(1):291-297. doi: 10.1111/head.13696. Epub 2019 Nov 14. Headache. 2020. PMID: 31724752 Review.
Possible mechanisms include cerebral vasodilation-associated stretching of the vessel nociceptors, sensitization of perivascular nociceptors mediated by nitric oxide, cerebral calcitonin gene-related peptide, activation of the cyclic adenosine monophosphate pathway, cortic …
Possible mechanisms include cerebral vasodilation-associated stretching of the vessel nociceptors, sensitization of perivascular noci …
Methylene blue and epinephrine: a synergetic association for anaphylactic shock treatment.
Zheng F, Barthel G, Collange O, Montémont C, Thornton SN, Longrois D, Levy B, Audibert G, Malinovsky JM, Mertes PM. Zheng F, et al. Crit Care Med. 2013 Jan;41(1):195-204. doi: 10.1097/CCM.0b013e318267667b. Crit Care Med. 2013. PMID: 23222265
Refractoriness to epinephrine could be corrected by nitric oxide pathway inhibitors such as methylene blue. OBJECTIVES: To compare the systemic and regional (brain and skeletal muscle) effects of epinephrine and methylene blue given alone or in combina …
Refractoriness to epinephrine could be corrected by nitric oxide pathway inhibitors such as methylene blue. OBJECTIVES: To com …
Photodynamic therapy for endodontic disinfection.
Soukos NS, Chen PS, Morris JT, Ruggiero K, Abernethy AD, Som S, Foschi F, Doucette S, Bammann LL, Fontana CR, Doukas AG, Stashenko PP. Soukos NS, et al. J Endod. 2006 Oct;32(10):979-84. doi: 10.1016/j.joen.2006.04.007. Epub 2006 Jul 13. J Endod. 2006. PMID: 16982278
Strains of microorganisms were sensitized with methylene blue (25 microg/ml) for 5 minutes followed by exposure to red light of 665 nm with an energy fluence of 30 J/cm2. Methylene blue fully eliminated all bacterial species with the exception o …
Strains of microorganisms were sensitized with methylene blue (25 microg/ml) for 5 minutes followed by exposure to red …
Possible Biological and Clinical Applications of Phenothiazines.
Varga B, Csonka Á, Csonka A, Molnár J, Amaral L, Spengler G. Varga B, et al. Anticancer Res. 2017 Nov;37(11):5983-5993. doi: 10.21873/anticanres.12045. Anticancer Res. 2017. PMID: 29061777 Review.
Phenothiazines have also been proven to destroy cancer cells and sensitize them to chemotherapy. Anti-angiogenesis and anticancer stem cell activities have also been reported, and they might be applied as adjuvants in the treatment of infections and tumors in the fu …
Phenothiazines have also been proven to destroy cancer cells and sensitize them to chemotherapy. Anti-angiogenesis and antican …
Evaluation of methylene blue based photodynamic inactivation (PDI) against intracellular B-CoV and SARS-CoV2 viruses under different light sources in vitro as a basis for new local treatment strategies in the early phase of a Covid19 infection.
Arentz J, von der Heide HJ. Arentz J, et al. Photodiagnosis Photodyn Ther. 2022 Mar;37:102642. doi: 10.1016/j.pdpdt.2021.102642. Epub 2021 Dec 2. Photodiagnosis Photodyn Ther. 2022. PMID: 34863949 Free PMC article.
The aim of our study was to find a simplified PDI therapy option against corona viruses in this region with low dose methylene blue (MB) as photosensitizer and use of LED light instead of laser. ...We used an 810nm diode laser with 300mW/cm2 and 100J/cm(2) li …
The aim of our study was to find a simplified PDI therapy option against corona viruses in this region with low dose methylene …
Nanoparticle-based endodontic antimicrobial photodynamic therapy.
Pagonis TC, Chen J, Fontana CR, Devalapally H, Ruggiero K, Song X, Foschi F, Dunham J, Skobe Z, Yamazaki H, Kent R, Tanner AC, Amiji MM, Soukos NS. Pagonis TC, et al. J Endod. 2010 Feb;36(2):322-8. doi: 10.1016/j.joen.2009.10.011. Epub 2009 Dec 16. J Endod. 2010. PMID: 20113801 Free PMC article.
OBJECTIVE: To study the in vitro effects of poly(lactic-co-glycolic acid) (PLGA) nanoparticles loaded with the photosensitizer methylene blue (MB) and light against Enterococcus faecalis (ATCC 29212). MATERIALS AND METHODS: The uptake and distribution of nanoparticl …
OBJECTIVE: To study the in vitro effects of poly(lactic-co-glycolic acid) (PLGA) nanoparticles loaded with the photosensitizer methylene …
Lysosomal-Targeting and Light/Ultrasound Sensitive Carbon Dots for Combined Photodynamic and Sonodynamic Therapies of Breast Tumor.
Qin W, Cui J, Usama, Li Y, Liu R, Miao Z, Zha Z, Jiang L, Cao M, Tadros MI, Tedesco AC, Li Z, Bi H. Qin W, et al. Adv Healthc Mater. 2025 Nov;14(28):e02873. doi: 10.1002/adhm.202502873. Epub 2025 Jul 29. Adv Healthc Mater. 2025. PMID: 40734306
The combination of photodynamic therapy (PDT) with sonodynamic therapy (SDT) can compensate for shortcomings of PDT, such as the limited tissue penetration depth or low efficiency of reactive oxygen species (ROS) generation of SDT, but it is still a great challenge …
The combination of photodynamic therapy (PDT) with sonodynamic therapy (SDT) can compensate for shortcomings of PDT, such as t …
Endodontic photodynamic therapy ex vivo.
Ng R, Singh F, Papamanou DA, Song X, Patel C, Holewa C, Patel N, Klepac-Ceraj V, Fontana CR, Kent R, Pagonis TC, Stashenko PP, Soukos NS. Ng R, et al. J Endod. 2011 Feb;37(2):217-22. doi: 10.1016/j.joen.2010.10.008. J Endod. 2011. PMID: 21238805 Free PMC article.
INTRODUCTION: The objective of this study was to evaluate the antimicrobial effects of photodynamic therapy (PDT) on infected human teeth ex vivo. METHODS: Fifty-two freshly extracted teeth with pulpal necrosis and associated periradicular radiolucencies were obtained from …
INTRODUCTION: The objective of this study was to evaluate the antimicrobial effects of photodynamic therapy (PDT) on infected human t …
Photodynamic antifungal therapy against chromoblastomycosis.
Lyon JP, Pedroso e Silva Azevedo Cde M, Moreira LM, de Lima CJ, de Resende MA. Lyon JP, et al. Mycopathologia. 2011 Oct;172(4):293-7. doi: 10.1007/s11046-011-9434-6. Epub 2011 Jun 4. Mycopathologia. 2011. PMID: 21643843
The activation of the sensitizer drug results in several chemical reactions, such as the production of reactive oxygen species and other reactive molecules, which presence in the biological site leads to the damage of target cells. ...In the present work, the clinic …
The activation of the sensitizer drug results in several chemical reactions, such as the production of reactive oxygen species …
82 results