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1991 1
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30 results

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Page 1
Plasma temperature during methylene blue/light treatment influences virus inactivation capacity and product quality.
Gravemann U, Handke W, Sumian C, Alvarez I, Reichenberg S, Müller TH, Seltsam A. Gravemann U, et al. Vox Sang. 2018 May;113(4):368-377. doi: 10.1111/vox.12643. Epub 2018 Feb 27. Vox Sang. 2018. PMID: 29484670
BACKGROUND: Photodynamic treatment using methylene blue (MB) and visible light is in routine use for pathogen inactivation of human plasma in different countries. ...Inactivation of cooled plasma is not recommended....
BACKGROUND: Photodynamic treatment using methylene blue (MB) and visible light is in routine use for pathogen inacti
Hepatitis E virus is effectively inactivated by methylene blue plus light treatment.
Gravemann U, Engelmann M, Kinast V, Burkard T, Behrendt P, Schulze TJ, Todt D, Steinmann E. Gravemann U, et al. Transfusion. 2022 Nov;62(11):2200-2204. doi: 10.1111/trf.17108. Epub 2022 Sep 20. Transfusion. 2022. PMID: 36125237
BACKGROUND AND OBJECTIVES: Photodynamic treatment with methylene blue (MB) and visible light is a well-established pathogen inactivation system for human plasma. This technique is routinely used in different countries. MB/light treatment was sho …
BACKGROUND AND OBJECTIVES: Photodynamic treatment with methylene blue (MB) and visible light is a well-established path …
[The effect of methylene blue/photochemical method for virus inactivation on plasma components].
Zhou XP, Xu JB, Sun P, Yan F, Wang QL, Bu FR. Zhou XP, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2003 Jun;11(3):305-7. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2003. PMID: 12844419 Chinese.
Virus inactivation of plasma can be achieved by methylene blue/photochemical method. To investigate the effect of this method on immunological properties and biochemical functions of plasma components, the virus-inactivation
Virus inactivation of plasma can be achieved by methylene blue/photochemical method. To investigate the e
Photodynamic inactivation of model virus in human plasma by methylene blue and its influence on plasma proteins.
Wang D, Bu F, Xu J. Wang D, et al. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2000 Mar;14(1):52-5. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2000. PMID: 11503026
Small amount experiments were carried out to observe virus inactivation and the influence on plasma proteins. RESULTS: Methylene blue (MB) in combination with visible light can inactivate the model virus in human plasma effi …
Small amount experiments were carried out to observe virus inactivation and the influence on plasma proteins. RESULTS: …
Anti-Viral Photodynamic Inactivation of T4-like Bacteriophage as a Mammalian Virus Model in Blood.
Santos P, Gomes ATPC, Lourenço LMO, Faustino MAF, Neves MGPMS, Almeida A. Santos P, et al. Int J Mol Sci. 2022 Sep 30;23(19):11548. doi: 10.3390/ijms231911548. Int J Mol Sci. 2022. PMID: 36232850 Free PMC article.
The laboratorial available methods applied in plasma disinfection can induce damage in other blood components. Antimicrobial photodynamic therapy (aPDT) represents a promising approach and is approved for plasma and platelet disinfection using non-porphyrinic …
The laboratorial available methods applied in plasma disinfection can induce damage in other blood components. Antimicrobial photo
Target structures for HIV-1 inactivation by methylene blue and light.
Bachmann B, Knüver-Hopf J, Lambrecht B, Mohr H. Bachmann B, et al. J Med Virol. 1995 Oct;47(2):172-8. doi: 10.1002/jmv.1890470211. J Med Virol. 1995. PMID: 8830122
In a photodynamic virus inactivation procedure for human fresh frozen plasma the plasma is exposed to visible light in the presence of 1 microM methylene blue. ...In the dark, methylene blue up to 10 microM has no inh …
In a photodynamic virus inactivation procedure for human fresh frozen plasma the plasma is exposed to vis …
[Optimizing parameters in photodynamic virus inactivation of fresh frozen plasma].
Mohr H, Lambrecht B, Schmitt H. Mohr H, et al. Beitr Infusionsther. 1993;31:25-30. Beitr Infusionsther. 1993. PMID: 7693260 German.
Fresh plasma from single-blood donations is virus-inactivated by illuminating the plasma units in their respective plastic bags with visible light for 1 h in the presence of 1 microM of the photoactive dye methylene blue. ...These finding …
Fresh plasma from single-blood donations is virus-inactivated by illuminating the plasma units in their respecti …
[Methylene blue/light treatment of virus inactivated human plasma: production and clinical experience].
Mohr H, Pohl U, Lambrecht B, Wieding JU, Schmitt H. Mohr H, et al. Infusionsther Transfusionsmed. 1993 Jun;20 Suppl 2:19-24. Infusionsther Transfusionsmed. 1993. PMID: 8374283 German.
A photodynamic procedure to inactivate viruses in fresh plasma for therapeutical use is carried out by illuminating single units of plasma with visible light in the presence of the phenothiazine dye methylene blue. ...Under the cho …
A photodynamic procedure to inactivate viruses in fresh plasma for therapeutical use is carried out by illuminat …
West Nile virus in plasma is highly sensitive to methylene blue-light treatment.
Mohr H, Knüver-Hopf J, Gravemann U, Redecker-Klein A, Müller TH. Mohr H, et al. Transfusion. 2004 Jun;44(6):886-90. doi: 10.1111/j.1537-2995.2004.03424.x. Transfusion. 2004. PMID: 15157256
BACKGROUND: The epidemic of West Nile virus (WNV) in the US resulted in cases of transfusion-transmitted WNV. Effective pathogen reduction methods could have removed this infectious agent from the blood supply We have evaluated the efficacy of photodynamic treatment …
BACKGROUND: The epidemic of West Nile virus (WNV) in the US resulted in cases of transfusion-transmitted WNV. Effective pathogen redu …
Transfusing methylene blue-photoinactivated plasma instead of FFP is associated with an increased demand for plasma and cryoprecipitate.
Atance R, Pereira A, Ramírez B. Atance R, et al. Transfusion. 2001 Dec;41(12):1548-52. doi: 10.1046/j.1537-2995.2001.41121548.x. Transfusion. 2001. PMID: 11778070
BACKGROUND: Photodynamic virus inactivation of plasma with methylene blue significantly decreases the recovery of fibrinogen and coagulation factors V and VIII. ...It is possible that such an increase overrode the potential health benefit …
BACKGROUND: Photodynamic virus inactivation of plasma with methylene blue significantly decreases …
30 results