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Methylene blue for septic shock in oncologic patients: A propensity score-matched cohort.
Melo RH, Galantier J, Romano MLP, Romano ER, Felicio APV, da Hora Passos R, Gioli-Pereira L, de Azevedo LCP. Melo RH, et al. J Crit Care. 2026 Aug;94:155607. doi: 10.1016/j.jcrc.2026.155607. Epub 2026 May 3. J Crit Care. 2026. PMID: 42081873 Free article.
BACKGROUND AND AIMS: Septic shock is associated with high mortality, yet evidence supporting adjunctive therapies remains limited. ...Septic shock requiring multiple vasopressors was defined as septic shock requiring norepinephrine plus a …
BACKGROUND AND AIMS: Septic shock is associated with high mortality, yet evidence supporting adjunctive therapies remains limi …
36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016.
Bateman RM, Sharpe MD, Jagger JE, Ellis CG, Solé-Violán J, López-Rodríguez M, Herrera-Ramos E, Ruíz-Hernández J, Borderías L, Horcajada J, González-Quevedo N, Rajas O, Briones M, Rodríguez de Castro F, Rodríguez Gallego C, Esen F, Orhun G, Ergin Ozcan P, Senturk E, Ugur Yilmaz C, Orhan N, Arican N, Kaya M, Kucukerden M, Giris M, Akcan U, Bilgic Gazioglu S, Tuzun E, Riff R, Naamani O, Douvdevani A, Takegawa R, Yoshida H, Hirose T, Yamamoto N, Hagiya H, Ojima M, Akeda Y, Tasaki O, Tomono K, Shimazu T, Ono S, Kubo T, Suda S, Ueno T, Ikeda T, Hirose T, Ogura H, Takahashi H, Ojima M, Kang J, Nakamura Y, Kojima T, Shimazu T, Ikeda T, Suda S, Izutani Y, Ueno T, Ono S, Taniguchi T, O M, Dinter C, Lotz J, Eilers B, Wissmann C, Lott R, Meili MM, Schuetz PS, Hawa H, Sharshir M, Aburageila M, Salahuddin N, Chantziara V, Georgiou S, Tsimogianni A, Alexandropoulos P, Vassi A, Lagiou F, Valta M, Micha G, Chinou E, Michaloudis G, Kodaira A, Ikeda T, Ono S, Ueno T, Suda S, Izutani Y, Imaizumi H, De la Torre-Prados MV, Garcia-De la Torre A, Enguix-Armada A, Puerto-Morlan A, Perez-Valero V, Garcia-Alcantara A, Bolton N, Dudziak J, Bonney S, Tridente A, Nee P, Nicolaes G, Wiewel M, Schultz M, Wildhag… See abstract for full author list ➔ Bateman RM, et al. Crit Care. 2016 Apr 20;20(Suppl 2):94. doi: 10.1186/s13054-016-1208-6. Crit Care. 2016. PMID: 27885969 Free PMC article.
Preda, R. Boschi, L. Carnevale P050 - Methylene blue effectiveness as contributory treatment in patients with septic shock V. ...Abdellatif, F. Daly, R. Nasri, S. Ben Lakhal P101 - Septic shock is an independent risk factor for colistin-i …
Preda, R. Boschi, L. Carnevale P050 - Methylene blue effectiveness as contributory treatment in patients with septic …
ADJUNCTIVE VASOPRESSORS AND SHORT-TERM MORTALITY IN ADULTS WITH SEPTIC SHOCK: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Bauer SR, Wieruszewski PM, Bissell Turpin BD, Dugar S, Sacha GL, Sato R, Siuba MT, Schleicher M, Vachharajani V, Falck-Ytter Y, Morgan RL. Bauer SR, et al. Shock. 2025 May 1;63(5):668-676. doi: 10.1097/SHK.0000000000002558. Epub 2025 Feb 7. Shock. 2025. PMID: 39965613 Free PMC article.
We included randomized clinical trials of adults with septic shock comparing adjunctive treatment with a vasopressin analogue, angiotensin II, methylene blue, hydroxocobalamin, or catecholamine analog to standard care vasopressors. ...The findings were …
We included randomized clinical trials of adults with septic shock comparing adjunctive treatment with a vasopressin analogue, …
Can Use of Intravenous Methylene Blue Improve the Hemodynamics and Outcome of the Patients with Refractory Septic Shock? An Observational Study.
Rajbanshi LK, Bajracharya A, Arjyal B, Devkota D. Rajbanshi LK, et al. Indian J Crit Care Med. 2023 Sep;27(9):669-674. doi: 10.5005/jp-journals-10071-24535. Indian J Crit Care Med. 2023. PMID: 37719353 Free PMC article.
Methylene blue has emerged as a potential adjunctive treatment option for reversing refractory shock in sepsis. ...HOW TO CITE THIS ARTICLE: Rajbanshi LK, Bajracharya A, Arjyal B, Devkota D. Can Use of Intravenous Methylene Blue Improve the Hemo …
Methylene blue has emerged as a potential adjunctive treatment option for reversing refractory shock in sepsis. ...HOW …
Use of methylene blue for refractory septic shock during continuous venovenous hemodiafiltration.
Mount JC, Rowe AS. Mount JC, et al. Pharmacotherapy. 2010 Mar;30(3):323. doi: 10.1592/phco.30.3.323. Pharmacotherapy. 2010. PMID: 20180614
As an inhibitor of nitric oxide, methylene blue has been investigated as an alternative vasopressor in patients with septic shock refractory to catecholamine vasopressors and as an agent to maintain hemodynamic stability in patients receiving intermitt …
As an inhibitor of nitric oxide, methylene blue has been investigated as an alternative vasopressor in patients with septic …
Short-term beneficial effects of methylene blue on kidney damage in septic shock patients.
Heemskerk S, van Haren FM, Foudraine NA, Peters WH, van der Hoeven JG, Russel FG, Masereeuw R, Pickkers P. Heemskerk S, et al. Intensive Care Med. 2008 Feb;34(2):350-4. doi: 10.1007/s00134-007-0867-9. Epub 2007 Oct 10. Intensive Care Med. 2008. PMID: 17926021 Free PMC article.
In this study we investigated the short-term effect of methylene blue (MB), an inhibitor of the NO pathway, on kidney damage and function in septic shock patients. ...PATIENTS: Nine patients (four men, five women, mean age 71 +/- 3 years) with c …
In this study we investigated the short-term effect of methylene blue (MB), an inhibitor of the NO pathway, on kidney d …
Adjunctive Vasopressors in Patients with Septic Shock: Protocol for a Systematic Review and Meta-Analysis.
Bauer SR, Wieruszewski PM, Bissell BD, Dugar S, Sacha GL, Sato R, Siuba MT, Schleicher M, Vachharajani V, Falck-Ytter Y, Morgan RL. Bauer SR, et al. medRxiv [Preprint]. 2023 Jul 30:2023.07.29.23293364. doi: 10.1101/2023.07.29.23293364. medRxiv. 2023. PMID: 37546921 Free PMC article. Preprint.
This review aims to overcome the limitations of previous reviews by systematically synthesizing the direct evidence for adjunctive vasopressor therapy use in adult patients with septic shock. METHODS: We will conduct a systematic review and meta-analysis of randomiz …
This review aims to overcome the limitations of previous reviews by systematically synthesizing the direct evidence for adjunctive vasopress …
Early use of methylene blue in the management of refractory group A streptococcal toxic shock syndrome with multi-organ failure in the intensive care unit.
Steinbrook E, Labar AS, Mendoza H, Ghincea A. Steinbrook E, et al. BMJ Case Rep. 2026 Apr 3;19(4):e271683. doi: 10.1136/bcr-2025-271683. BMJ Case Rep. 2026. PMID: 41932711
The early initiation of methylene blue was associated with his rapid stabilisation and improvement. He was found to have an upper extremity wound with group A Streptococcus, leading to the diagnosis of group A Streptococcus toxic shock syndrome. We share this …
The early initiation of methylene blue was associated with his rapid stabilisation and improvement. He was found to have an up …
Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report.
Faisal H, Bloom A, Gaber AO. Faisal H, et al. A A Pract. 2020 Jul;14(9):e01287. doi: 10.1213/XAA.0000000000001287. A A Pract. 2020. PMID: 32909713 Free PMC article.
Hypoxia and methemoglobinemia did not respond to methylene blue and required administration of packed red blood cell transfusions....
Hypoxia and methemoglobinemia did not respond to methylene blue and required administration of packed red blood cell transfusi …
[Late methylene blue appearance in urine after local treatment of cutaneous fistula in hip osteomyelitis as a first sign of renal failure].
Cvetković BR, Cvetković VR, Rosić ZV, Milenković D. Cvetković BR, et al. Acta Chir Iugosl. 2008;55(4):117-20. doi: 10.2298/aci0804117c. Acta Chir Iugosl. 2008. PMID: 19245153 Serbian.
Methylene blue is a dark green crystal. In medicine it is used as water or alcohol solution. Methaemoglobinemia, hypotension, septic shock are some of many diseases that are treated with methylene blue. In surgery methylene blue …
Methylene blue is a dark green crystal. In medicine it is used as water or alcohol solution. Methaemoglobinemia, hypotension, …
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