[Methylene blue therapy for vasoplegia after cardiac surgery].
Anestezjol Intens Ter. 2009.
PMID: 19999604
Polish.
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Pro: methylene blue as a rescue therapy for vasoplegia after cardiac surgery.
J Cardiothorac Vasc Anesth. 2011.
PMID: 21684764
No abstract available.
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Vasoplegia: A Review.
Methodist Debakey Cardiovasc J. 2023 Aug 1;19(4):38-47. doi: 10.14797/mdcvj.1245. eCollection 2023.
Methodist Debakey Cardiovasc J. 2023.
PMID: 37547893
Free PMC article.
Review.
Vasoplegia may occur due to various conditions, including cardiac failure, sepsis, and post-cardiac surgery. ...Early identification and prompt management of vasoplegia is crucial to prevent development of shock. This review expands upon the dif …
Vasoplegia may occur due to various conditions, including cardiac failure, sepsis, and post-cardiac surgery. ... …
Methylene Blue as an Adjunct to Treat Vasoplegia in Patients Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass: A Literature Review.
AANA J. 2018 Dec;86(6):455-463.
AANA J. 2018.
PMID: 31584419
The term vasoplegia describes hypotension refractory to vasopressor therapy, a common finding related to cardiac surgery requiring cardiopulmonary bypass. ...Its favorable safety profile as well as hemodynamic effects have made methylene blue a …
The term vasoplegia describes hypotension refractory to vasopressor therapy, a common finding related to cardiac surgery …
Methylene Blue Reduces Mortality in Critically Ill and Perioperative Patients: A Meta-Analysis of Randomized Trials.
J Cardiothorac Vasc Anesth. 2024 Jan;38(1):268-274. doi: 10.1053/j.jvca.2023.09.037. Epub 2023 Oct 1.
J Cardiothorac Vasc Anesth. 2024.
PMID: 37880041
Review.
As a nitric oxide production inhibitor, methylene blue (MB) exerts its vasoconstrictor property and is an adjuvant for catecholamine-refractory vasodilatory shock. ...Nine out of the 11 included randomized trials reported mortality, which was significantly lower in …
As a nitric oxide production inhibitor, methylene blue (MB) exerts its vasoconstrictor property and is an adjuvant for catecho …
Hydroxocobalamin for Vasodilatory Hypotension in Shock: A Systematic Review With Meta-Analysis for Comparison to Methylene Blue.
J Cardiothorac Vasc Anesth. 2023 Sep;37(9):1757-1772. doi: 10.1053/j.jvca.2023.04.006. Epub 2023 Apr 7.
J Cardiothorac Vasc Anesth. 2023.
PMID: 37147207
Hydroxocobalamin was applied mainly for cardiac surgery vasoplegia, but also was reported in the settings of liver transplantation, septic shock, drug-induced hypotension, and noncardiac postoperative vasoplegia. ...Hydroxocobalamin appears to positive …
Hydroxocobalamin was applied mainly for cardiac surgery vasoplegia, but also was reported in the settings of liver tran …
The mystery of methylene blue and its role in managing post-cardiac surgery vasoplegic shock.
Ann Med. 2025 Dec;57(1):2460770. doi: 10.1080/07853890.2025.2460770. Epub 2025 Feb 4.
Ann Med. 2025.
PMID: 39903510
Free PMC article.
BACKGROUND: Vasoplegic syndrome is associated with high mortality. Methylene blue (MB) is a guanylate cyclase inhibitor that ameliorates this re-distributive type of shock. ...The methylene blue group had a decreased 24-hour norepinephrine dose (1.5 …
BACKGROUND: Vasoplegic syndrome is associated with high mortality. Methylene blue (MB) is a guanylate cyclase inhibitor that a …
Non-adrenergic vasopressors for vasodilatory shock or perioperative vasoplegia: a meta-analysis of randomized controlled trials.
Crit Care. 2024 Dec 30;28(1):439. doi: 10.1186/s13054-024-05212-7.
Crit Care. 2024.
PMID: 39736782
Free PMC article.
Each eligible study was categorized into septic shock, cardiac surgery, or non-cardiac surgery. Non-adrenergic vasopressors included vasopressin, terlipressin, selepressin, angiotensin II, methylene blue, and hydroxocobalamin. ...RESULTS: …
Each eligible study was categorized into septic shock, cardiac surgery, or non-cardiac surgery. Non-adrenergic v …
Postoperative Serotonin Syndrome Following Methylene Blue Administration for Vasoplegia After Cardiac Surgery: A Case Report and Review of the Literature.
Semin Cardiothorac Vasc Anesth. 2021 Mar;25(1):51-56. doi: 10.1177/1089253220960255. Epub 2020 Sep 21.
Semin Cardiothorac Vasc Anesth. 2021.
PMID: 32951524
Review.
This case report describes the occurrence of postoperative serotonin syndrome in a patient on long-term sertraline who underwent coronary artery bypass graft and was treated with methylene blue for perioperative vasoplegia. It delineates the various clinical …
This case report describes the occurrence of postoperative serotonin syndrome in a patient on long-term sertraline who underwent coronary ar …
Vasoplegic syndrome after cardiovascular surgery: A review of pathophysiology and outcome-oriented therapeutic management.
J Card Surg. 2021 Oct;36(10):3749-3760. doi: 10.1111/jocs.15805. Epub 2021 Jul 12.
J Card Surg. 2021.
PMID: 34251716
AIMS: The aims of this systematic review are to collect all the clinically relevant data to describe the VPS, its potential risk factors, pathophysiology after CPB, and to assess the efficacy, safety, and outcome of the therapeutic management with catecholamine and non-catecholam …
AIMS: The aims of this systematic review are to collect all the clinically relevant data to describe the VPS, its potential risk factors, pa …
Vasoplegic syndrome following cardiothoracic surgery-review of pathophysiology and update of treatment options.
Crit Care. 2020 Feb 4;24(1):36. doi: 10.1186/s13054-020-2743-8.
Crit Care. 2020.
PMID: 32019600
Free PMC article.
Review.
Vasoplegic syndrome is a common occurrence following cardiothoracic surgery and is characterized as a high-output shock state with poor systemic vascular resistance. ...
Vasoplegic syndrome is a common occurrence following cardiothoracic surgery and is characterized as a high-output shock state with po …
Intraoperative vasoplegia: methylene blue to the rescue!
Curr Opin Anaesthesiol. 2018 Feb;31(1):43-49. doi: 10.1097/ACO.0000000000000548.
Curr Opin Anaesthesiol. 2018.
PMID: 29176374
Review.
PURPOSE OF REVIEW: To evaluate the efficacy, dosing, and safety of methylene blue (MTB) in perioperative vasoplegic syndrome (VS). RECENT FINDINGS: Vasoplegic syndrome is a state of persistent hypotension with elevated cardiac output, low filling pressures, a …
PURPOSE OF REVIEW: To evaluate the efficacy, dosing, and safety of methylene blue (MTB) in perioperative vasoplegic syndrome ( …
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