Functional vitamin B12 deficiency: Improving methylmalonic acid reference intervals in urine.
Clin Chim Acta. 2023.
PMID: 37031782
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Page 1
Vitamin B12 Deficiency: Recognition and Management.
Am Fam Physician. 2017 Sep 15;96(6):384-389.
Am Fam Physician. 2017.
PMID: 28925645
Free article.
Vitamin B12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations. ...Initial laboratory assessment should include a complete blood count and serum vitamin B12 level. Measurement of serum …
Vitamin B12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manife …
Excess Folic Acid and Vitamin B12 Deficiency: Clinical Implications?
Food Nutr Bull. 2024 Jun;45(1_suppl):S67-S72. doi: 10.1177/03795721241229503.
Food Nutr Bull. 2024.
PMID: 38987872
Free PMC article.
Review.
RESULTS: Cognitive function test scores are lower and blood homocysteine and methylmalonic acid concentrations are higher in people with low B12 and elevated folate than in those with low B12 and nonelevated folate. ...Plain language titleExcess …
RESULTS: Cognitive function test scores are lower and blood homocysteine and methylmalonic acid concentrations are high …
Clinical practice. Vitamin B12 deficiency.
N Engl J Med. 2013 Jan 10;368(2):149-60. doi: 10.1056/NEJMcp1113996.
N Engl J Med. 2013.
PMID: 23301732
Review.
No abstract available.
Vitamin B(12) deficiency.
Nat Rev Dis Primers. 2017 Jun 29;3:17040. doi: 10.1038/nrdp.2017.40.
Nat Rev Dis Primers. 2017.
PMID: 28660890
Review.
B12 deficiency can affect individuals at all ages, but most particularly elderly individuals. ...Diagnostic biomarkers for B12 status include decreased levels of circulating total B12 and transcobalamin-bound B12, and abnormally increased levels …
B12 deficiency can affect individuals at all ages, but most particularly elderly individuals. ...Diagnostic biomarkers for …
Vitamin B12 deficiency.
Am Fam Physician. 2003 Mar 1;67(5):979-86.
Am Fam Physician. 2003.
PMID: 12643357
Free article.
Review.
Diagnosis of vitamin B12 deficiency is typically based on measurement of serum vitamin B12 levels; however, about 50 percent of patients with subclinical disease have normal B12 levels. A more sensitive method of screening for vitamin B12 def …
Diagnosis of vitamin B12 deficiency is typically based on measurement of serum vitamin B12 levels; however, about 50 pe …
Methylmalonic acid in aging and disease.
Trends Endocrinol Metab. 2024 Mar;35(3):188-200. doi: 10.1016/j.tem.2023.11.001. Epub 2023 Nov 28.
Trends Endocrinol Metab. 2024.
PMID: 38030482
Free PMC article.
Review.
Metabolic byproducts have conventionally been disregarded as waste products without functions. In this opinion article, we bring to light the multifaceted role of methylmalonic acid (MMA), a byproduct of the propionate metabolism pathway mostly commonly known …
Metabolic byproducts have conventionally been disregarded as waste products without functions. In this opinion article, we bring to l …
Vitamin B12 deficiency.
BMJ. 2014 Sep 4;349:g5226. doi: 10.1136/bmj.g5226.
BMJ. 2014.
PMID: 25189324
Review.
No abstract available.
Functional vitamin B12 deficiency: Improving methylmalonic acid reference intervals in urine.
Clin Chim Acta. 2023 Apr 1;544:117334. doi: 10.1016/j.cca.2023.117334. Epub 2023 Apr 7.
Clin Chim Acta. 2023.
PMID: 37031782
BACKGROUND-AIM: Most laboratory requests focus on the detection of possible vitamin B12 deficiency. In this context, methylmalonic acid (MMA) is reported as the best biomarker. ...RESULTS: It was established a single reference interval [0.52 (CI(90%): …
BACKGROUND-AIM: Most laboratory requests focus on the detection of possible vitamin B12 deficiency. In this context, methyl …
A Brief Overview of the Diagnosis and Treatment of Cobalamin (B12) Deficiency.
Food Nutr Bull. 2024 Jun;45(1_suppl):S40-S49. doi: 10.1177/03795721241229500.
Food Nutr Bull. 2024.
PMID: 38987879
Review.
RESULTS: Prevention and early treatment of B12 deficiency is essential to avoid irreversible neurological consequences. Diagnosis is often difficult due to diverse symptoms, marked differences in diagnostic assays' performance and the unreliability of second-line bi …
RESULTS: Prevention and early treatment of B12 deficiency is essential to avoid irreversible neurological consequences. Diagno …
Association of vitamin B12, methylmalonic acid, and functional parameters.
Neth J Med. 2020 Feb;78(1):10-24.
Neth J Med. 2020.
PMID: 32043474
Free article.
INTRODUCTION: Diagnosis of vitamin B12 deficiency is difficult, as there is no conclusive single test for this disorder. We evaluated the association of serum B12 and methylmalonic acid (MMA) with haematologic parameters and physical and cogniti …
INTRODUCTION: Diagnosis of vitamin B12 deficiency is difficult, as there is no conclusive single test for this disorder. We ev …
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