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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 4
1955 3
1956 26
1957 39
1958 37
1959 31
1960 16
1961 22
1962 51
1963 37
1964 38
1965 28
1966 36
1967 31
1968 35
1969 29
1970 31
1971 57
1972 55
1973 76
1974 85
1975 101
1976 87
1977 78
1978 71
1979 101
1980 79
1981 77
1982 73
1983 83
1984 89
1985 82
1986 88
1987 73
1988 93
1989 93
1990 61
1991 94
1992 73
1993 88
1994 76
1995 90
1996 100
1997 108
1998 121
1999 151
2000 144
2001 170
2002 222
2003 204
2004 214
2005 265
2006 311
2007 364
2008 368
2009 385
2010 380
2011 403
2012 430
2013 488
2014 471
2015 419
2016 433
2017 447
2018 394
2019 389
2020 389
2021 386
2022 317
2023 314
2024 127

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10,312 results

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Page 1
An update on the clinical pharmacology of methylphenidate: therapeutic efficacy, abuse potential and future considerations.
Shellenberg TP, Stoops WW, Lile JA, Rush CR. Shellenberg TP, et al. Expert Rev Clin Pharmacol. 2020 Aug;13(8):825-833. doi: 10.1080/17512433.2020.1796636. Epub 2020 Jul 25. Expert Rev Clin Pharmacol. 2020. PMID: 32715789 Review.
INTRODUCTION: Methylphenidate remains a first-line medication for treating ADHD in children and adults. ...The development of abuse deterrent formulations of methylphenidate is warranted....
INTRODUCTION: Methylphenidate remains a first-line medication for treating ADHD in children and adults. ...The development of abuse d …
Psychopharmacology of Attention-Deficit Hyperactivity Disorder: Effects and Side Effects.
Golmirzaei J, Mahboobi H, Yazdanparast M, Mushtaq G, Kamal MA, Hamzei E. Golmirzaei J, et al. Curr Pharm Des. 2016;22(5):590-4. doi: 10.2174/1381612822666151124235816. Curr Pharm Des. 2016. PMID: 26601963 Review.
Methylphenidate significantly reduces ADHD symptoms in children both at home and school and improves their social skills. Methylphenidate is safe in healthy children and has shown to have no cardiac side effects in these patients. ...
Methylphenidate significantly reduces ADHD symptoms in children both at home and school and improves their social skills. Methylph …
Classics in Chemical Neuroscience: Methylphenidate.
Wenthur CJ. Wenthur CJ. ACS Chem Neurosci. 2016 Aug 17;7(8):1030-40. doi: 10.1021/acschemneuro.6b00199. Epub 2016 Jul 25. ACS Chem Neurosci. 2016. PMID: 27409720 Review.
As the first drug to see widespread use for the treatment of attention deficit hyperactivity disorder (ADHD), methylphenidate was the forerunner and catalyst to the modern era of rapidly increasing diagnosis, treatment, and medication development for this condition. ...In …
As the first drug to see widespread use for the treatment of attention deficit hyperactivity disorder (ADHD), methylphenidate was the …
Pharmacokinetics and clinical effectiveness of methylphenidate.
Kimko HC, Cross JT, Abernethy DR. Kimko HC, et al. Clin Pharmacokinet. 1999 Dec;37(6):457-70. doi: 10.2165/00003088-199937060-00002. Clin Pharmacokinet. 1999. PMID: 10628897 Review.
Methylphenidate is administered as a racemic mixture that undergoes stereoselective clearance. ...Methylphenidate is efficacious for short term treatment for children with ADHD. ...
Methylphenidate is administered as a racemic mixture that undergoes stereoselective clearance. ...Methylphenidate is efficacio …
Atomoxetine.
Unni JC. Unni JC. Indian Pediatr. 2006 Jul;43(7):603-6. Indian Pediatr. 2006. PMID: 16891679 Free article. Review. No abstract available.
Single-dose effects of methylphenidate and atomoxetine on functional connectivity during an n-back task in boys with ADHD.
Kowalczyk OS, Cubillo AI, Criaud M, Giampietro V, O'Daly OG, Mehta MA, Rubia K. Kowalczyk OS, et al. Psychopharmacology (Berl). 2023 Oct;240(10):2045-2060. doi: 10.1007/s00213-023-06422-7. Epub 2023 Jul 27. Psychopharmacology (Berl). 2023. PMID: 37500785 Free PMC article. Clinical Trial.
Additionally, methylphenidate has been observed to modulate functional networks involved in working memory. ...CONCLUSIONS: This study shows shared modulating effects of methylphenidate and atomoxetine on parieto-insular connectivity but exclusive effects of meth …
Additionally, methylphenidate has been observed to modulate functional networks involved in working memory. ...CONCLUSIONS: This stud …
Revisiting stimulant use for emotional dysregulation in attention-deficit/hyperactivity disorder (ADHD).
Brancati GE, Acierno D, Barbuti M, Elefante C, Gemignani S, Raia A, Perugi G. Brancati GE, et al. Expert Rev Neurother. 2023 Jul-Dec;23(11):981-994. doi: 10.1080/14737175.2023.2263645. Epub 2023 Oct 27. Expert Rev Neurother. 2023. PMID: 37747111 Review.
Comorbidity with disruptive behavior disorders (DBD) and disruptive mood dysregulation disorder does not prevent stimulant effectiveness. Methylphenidate has also been found to reduce temper problems, affective instability, and emotional over-reactivity in adults with ADHD …
Comorbidity with disruptive behavior disorders (DBD) and disruptive mood dysregulation disorder does not prevent stimulant effectiveness. …
Pre-clinical evidence that methylphenidate increases motivation and/or reward preference to search for high value rewards.
Pulido LN, Pochapski JA, Sugi A, Esaki JY, Stresser JL, Sanchez WN, Baltazar G, Levcik D, Fuentes R, Da Cunha C. Pulido LN, et al. Behav Brain Res. 2023 Feb 2;437:114065. doi: 10.1016/j.bbr.2022.114065. Epub 2022 Aug 28. Behav Brain Res. 2023. PMID: 36037842
Methylphenidate is a stimulant used to treat attention deficit and hyperactivity disorder (ADHD). ...However, the studies that aimed to assess the methylphenidate effects on memory are not consistent. Here, we tested whether the effect of methylphenidate on a …
Methylphenidate is a stimulant used to treat attention deficit and hyperactivity disorder (ADHD). ...However, the studies that aimed …
Examining the role of dopamine in methylphenidate's effects on resting brain function.
Tomasi D, Manza P, Yan W, Shokri-Kojori E, Demiral ŞB, Yonga MV, McPherson K, Biesecker C, Dennis E, Johnson A, Zhang R, Wang GJ, Volkow ND. Tomasi D, et al. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2314596120. doi: 10.1073/pnas.2314596120. Epub 2023 Dec 18. Proc Natl Acad Sci U S A. 2023. PMID: 38109535
Here we used, simultaneous PET-fMRI to examine the association between dynamic changes in striatal DA and brain activity as assessed by ALFF and gFCD, following placebo, intravenous (IV), or oral methylphenidate (MP) administration, using a within-subject double-blind plac …
Here we used, simultaneous PET-fMRI to examine the association between dynamic changes in striatal DA and brain activity as assessed by ALFF …
Methylphenidate and pregnancy.
Damkier P. Damkier P. Br J Clin Pharmacol. 2014 Jun;77(6):1083. doi: 10.1111/bcp.12238. Br J Clin Pharmacol. 2014. PMID: 24003978 Free PMC article. No abstract available.
10,312 results
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