Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 2
1971 2
1972 3
1973 8
1974 6
1975 13
1976 12
1977 9
1978 9
1979 8
1980 8
1981 9
1982 15
1983 24
1984 21
1985 24
1986 23
1987 29
1988 27
1989 28
1990 35
1991 43
1992 56
1993 70
1994 62
1995 43
1996 50
1997 54
1998 59
1999 54
2000 46
2001 53
2002 32
2003 44
2004 60
2005 56
2006 74
2007 60
2008 58
2009 57
2010 64
2011 64
2012 65
2013 60
2014 74
2015 89
2016 70
2017 71
2018 72
2019 55
2020 47
2021 81
2022 75
2023 59
2024 47
2025 61
2026 18

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

2,201 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study.
Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrich EF, Fazl M, Fehlings M, Herr DL, Hitchon PW, Marshall LF, Nockels RP, Pascale V, Perot PL Jr, Piepmeier J, Sonntag VK, Wagner F, Wilberger JE, Winn HR, Young W. Bracken MB, et al. JAMA. 1997 May 28;277(20):1597-604. JAMA. 1997. PMID: 9168289 Clinical Trial.
RESULTS: Compared with patients treated with methylprednisolone for 24 hours, those treated with methylprednisolone for 48 hours showed improved motor recovery at 6 weeks (P=.09) and 6 months (P=.07) after injury. ...When methylprednisolone is initiated 3 to …
RESULTS: Compared with patients treated with methylprednisolone for 24 hours, those treated with methylprednisolone for 48 hou …
Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis.
Jayne DR, Gaskin G, Rasmussen N, Abramowicz D, Ferrario F, Guillevin L, Mirapeix E, Savage CO, Sinico RA, Stegeman CA, Westman KW, van der Woude FJ, de Lind van Wijngaarden RA, Pusey CD; European Vasculitis Study Group. Jayne DR, et al. J Am Soc Nephrol. 2007 Jul;18(7):2180-8. doi: 10.1681/ASN.2007010090. Epub 2007 Jun 20. J Am Soc Nephrol. 2007. PMID: 17582159 Clinical Trial.
At 3 mo, 33 (49%) of 67 after intravenous methylprednisolone compared with 48 (69%) or 70 after plasma exchange were alive and independent of dialysis (95% confidence interval for the difference 18 to 35%; P = 0.02). As compared with intravenous methylprednisolone, …
At 3 mo, 33 (49%) of 67 after intravenous methylprednisolone compared with 48 (69%) or 70 after plasma exchange were alive and indepe …
Methylprednisolone, dexamethasone or hydrocortisone for acute severe pediatric asthma: does it matter?
Doymaz S, Ahmed YE, Francois D, Pinto R, Gist R, Steinberg M, Giambruno C. Doymaz S, et al. J Asthma. 2022 Mar;59(3):590-596. doi: 10.1080/02770903.2020.1870130. Epub 2021 Jan 16. J Asthma. 2022. PMID: 33380248 Clinical Trial.
In this study, we compared the efficacy of IV methylprednisolone, hydrocortisone and dexamethasone in ASA treatment during pediatric intensive care unit (PICU) admission. ...Median durations of beta-2-agonist treatment were 23 h (QR 16-38) for methylprednisolone, 27 …
In this study, we compared the efficacy of IV methylprednisolone, hydrocortisone and dexamethasone in ASA treatment during pediatric …
Methylprednisolone and local anesthetic for long-term postherpetic neuralgia: a meta-analysis.
Zhang Y, Gao YL, Zhang LH. Zhang Y, et al. J Dermatolog Treat. 2022 Sep;33(6):2723-2729. doi: 10.1080/09546634.2022.2067820. Epub 2022 Apr 26. J Dermatolog Treat. 2022. PMID: 35435114 Free article. Review.
OBJECTIVE: The purpose was to evaluate the efficacy of methylprednisolone combined with local anesthetics on the incidence or intensity of long-term Postherpetic neuralgia (PHN). ...In VAS scores, there was also a significant difference between the two groups in long-term …
OBJECTIVE: The purpose was to evaluate the efficacy of methylprednisolone combined with local anesthetics on the incidence or intensi …
Methylprednisolone for Infant Heart Surgery: Subpopulation Analyses of a Randomized Controlled Trial.
Sunthankar SD, Hill KD, Jacobs JP, Baldwin HS, Jacobs ML, Li JS, Graham EM, Blasiole B, Husain SA, Bleiweis MS, Mettler B, Benscoter A, Wald E, Karamlou T, Van Bergen AH, Eghtesady P, Scott JP, Anderson BR, Alfieris G, Vener DF, Kannankeril PJ. Sunthankar SD, et al. Crit Care Med. 2025 Jul 1;53(7):e1470-e1480. doi: 10.1097/CCM.0000000000006721. Epub 2025 May 21. Crit Care Med. 2025. PMID: 40396812 Free PMC article. Clinical Trial.
No increase in overall infection or reduction in prolonged mechanical ventilation with methylprednisolone. CONCLUSIONS: Both beneficial and adverse associations were observed with prophylactic methylprednisolone. Reduction in postoperative hydrocortisone administrat …
No increase in overall infection or reduction in prolonged mechanical ventilation with methylprednisolone. CONCLUSIONS: Both benefici …
Methylprednisolone versus dexamethasone in hospitalized patients with severe COVID-19: a systematic review and meta-analysis of randomized controlled trials.
Qin J, Wang G, Han D. Qin J, et al. Syst Rev. 2025 Nov 18;14(1):228. doi: 10.1186/s13643-025-02976-z. Syst Rev. 2025. PMID: 41254702 Free PMC article.
Randomized controlled trials (RCTs) on the treatment of severe COVID-19 with methylprednisolone, compared with dexamethasone, were included. Findings were summarized as risk ratios (RR) and mean differences (MD) with 95% confidence intervals (CI). ...Overall, using the GRA …
Randomized controlled trials (RCTs) on the treatment of severe COVID-19 with methylprednisolone, compared with dexamethasone, were in …
The roles of methylprednisolone treatment in patients with COVID-19: A systematic review and meta-analysis.
Hong S, Wang H, Zhang Z, Qiao L. Hong S, et al. Steroids. 2022 Jul;183:109022. doi: 10.1016/j.steroids.2022.109022. Epub 2022 Mar 26. Steroids. 2022. PMID: 35346661 Free PMC article.
The roles of methylprednisolone in treatment of patients with COVID-19 remain unclear. The aim of this study was to evaluate the efficacy and safety of methylprednisolone in treatment of COVID-19 patients. ...Patients with severe COVID-19 are more likely to benefit …
The roles of methylprednisolone in treatment of patients with COVID-19 remain unclear. The aim of this study was to evaluate the effi …
Does methylprednisolone reduce the mortality risk in hospitalized COVID-19 patients? A meta-analysis of randomized control trials.
Hasan SS, Kow CS, Mustafa ZU, Merchant HA. Hasan SS, et al. Expert Rev Respir Med. 2021 Aug;15(8):1049-1055. doi: 10.1080/17476348.2021.1925546. Epub 2021 Jul 2. Expert Rev Respir Med. 2021. PMID: 33945381
The pooled OR for all-cause mortality was 0.64 (95% CI: 0.29 - 1.43, n = 652) comparing methylprednisolone with the control, indicating no mortality benefits. A similar finding was noted with a sub-group analysis including four trials that used low-dose methylprednisolo …
The pooled OR for all-cause mortality was 0.64 (95% CI: 0.29 - 1.43, n = 652) comparing methylprednisolone with the control, indicati …
Methylprednisolone as Adjunct to Thrombectomy for Acute Intracranial Internal Carotid Artery Occlusion Stroke: Post Hoc Secondary Analysis of the MARVEL Randomized Clinical Trial.
Zheng C, Li R, Shen C, Guo F, Fan D, Yang L, Zhang L, Chen A, Chen Y, Chen D, Zi W, Guo C, Nguyen TN, Albers GW, Campbell BCV, Qiu Z, Hu Z. Zheng C, et al. JAMA Netw Open. 2025 Feb 3;8(2):e2459945. doi: 10.1001/jamanetworkopen.2024.59945. JAMA Netw Open. 2025. PMID: 39964685 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate the effectiveness and safety associated with intravenous methylprednisolone as adjunctive treatment to EVT for patients with AIS due to intracranial ICA occlusion. ...CONCLUSIONS AND RELEVANCE: In this secondary analysis of a randomized clinical t …
OBJECTIVE: To investigate the effectiveness and safety associated with intravenous methylprednisolone as adjunctive treatment to EVT …
2,201 results