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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
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1,637 results

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Page 1
Phase separation of EB1 guides microtubule plus-end dynamics.
Song X, Yang F, Yang T, Wang Y, Ding M, Li L, Xu P, Liu S, Dai M, Chi C, Xiang S, Xu C, Li D, Wang Z, Li L, Hill DL, Fu C, Yuan K, Li P, Zang J, Hou Z, Jiang K, Shi Y, Liu X, Yao X. Song X, et al. Nat Cell Biol. 2023 Jan;25(1):79-91. doi: 10.1038/s41556-022-01033-4. Epub 2022 Dec 19. Nat Cell Biol. 2023. PMID: 36536176
Here we show that EB1 formed molecular condensates through liquid-liquid phase separation (LLPS) to constitute the microtubule plus-end machinery. EB1 LLPS is driven by multivalent interactions among different segments, which are modulated by charged residues …
Here we show that EB1 formed molecular condensates through liquid-liquid phase separation (LLPS) to constitute the microtubule plu …
Microtubule plus-end tracking proteins in neuronal development.
van de Willige D, Hoogenraad CC, Akhmanova A. van de Willige D, et al. Cell Mol Life Sci. 2016 May;73(10):2053-77. doi: 10.1007/s00018-016-2168-3. Epub 2016 Mar 11. Cell Mol Life Sci. 2016. PMID: 26969328 Free PMC article. Review.
Regulation of the microtubule cytoskeleton is of pivotal importance for neuronal development and function. One such regulatory mechanism centers on microtubule plus-end tracking proteins (+TIPs): structurally and functionally diverse regulatory factors …
Regulation of the microtubule cytoskeleton is of pivotal importance for neuronal development and function. One such regulatory mechan …
Microtubule plus-end-tracking proteins: mechanisms and functions.
Akhmanova A, Hoogenraad CC. Akhmanova A, et al. Curr Opin Cell Biol. 2005 Feb;17(1):47-54. doi: 10.1016/j.ceb.2004.11.001. Curr Opin Cell Biol. 2005. PMID: 15661518 Review.
Microtubule plus-end-tracking proteins (+TIPs) are a diverse group of molecules that display dynamic accumulation at the distal ends of growing microtubules. Specific binding to the growing microtubule tip coupled with quick detachment from the …
Microtubule plus-end-tracking proteins (+TIPs) are a diverse group of molecules that display dynamic accumulation at th …
Microtubule plus-end tracking proteins in differentiated mammalian cells.
Jaworski J, Hoogenraad CC, Akhmanova A. Jaworski J, et al. Int J Biochem Cell Biol. 2008;40(4):619-37. doi: 10.1016/j.biocel.2007.10.015. Epub 2007 Oct 22. Int J Biochem Cell Biol. 2008. PMID: 18023603 Review.
These include molecular motors and non-motor proteins, some of which accumulate specifically at the growing microtubule plus-ends (the so-called microtubule plus-end tracking proteins). Plus-end tracking proteins can contribute to the reg …
These include molecular motors and non-motor proteins, some of which accumulate specifically at the growing microtubule plus-ends (th …
Microtubule plus-end tracking proteins and their roles in cell division.
Ferreira JG, Pereira AL, Maiato H. Ferreira JG, et al. Int Rev Cell Mol Biol. 2014;309:59-140. doi: 10.1016/B978-0-12-800255-1.00002-8. Int Rev Cell Mol Biol. 2014. PMID: 24529722 Review.
This is possible because of the inherent dynamic properties of microtubules. Many of these properties are tightly regulated by a number of microtubule plus-end-binding proteins or +TIPs. These proteins recognize the distal end of microtubules an …
This is possible because of the inherent dynamic properties of microtubules. Many of these properties are tightly regulated by a numb …
Plus-end-tracking proteins and their interactions at microtubule ends.
Galjart N. Galjart N. Curr Biol. 2010 Jun 22;20(12):R528-37. doi: 10.1016/j.cub.2010.05.022. Curr Biol. 2010. PMID: 20620909 Free article. Review.
In many cells, the microtubule network is organized in a radial manner, with one end of a microtubule (the minus end) embedded near the nucleus and the other end (the plus end) exploring cytoplasmic space, switching between episodes of growth and shrin …
In many cells, the microtubule network is organized in a radial manner, with one end of a microtubule (the minus end) embedded …
Microtubule minus-end-targeting proteins.
Akhmanova A, Hoogenraad CC. Akhmanova A, et al. Curr Biol. 2015 Feb 16;25(4):R162-71. doi: 10.1016/j.cub.2014.12.027. Curr Biol. 2015. PMID: 25689915 Free article. Review.
Microtubules are cytoskeletal filaments that are intrinsically polarized, with two structurally and functionally distinct ends, the plus end and the minus end. Over the last decade, numerous studies have shown that microtubule plus-end dy …
Microtubules are cytoskeletal filaments that are intrinsically polarized, with two structurally and functionally distinct ends, the …
Microtubule plus end: a hub of cellular activities.
Lansbergen G, Akhmanova A. Lansbergen G, et al. Traffic. 2006 May;7(5):499-507. doi: 10.1111/j.1600-0854.2006.00400.x. Traffic. 2006. PMID: 16643273 Free article. Review.
Growing MT plus ends accumulate a specific set of evolutionary conserved factors, the so-called MT plus-end-tracking proteins (+TIPs). +TIPs regulate MT dynamics and the reciprocal interactions of MTs with the cell cortex, mitotic kinetochores or different cellular …
Growing MT plus ends accumulate a specific set of evolutionary conserved factors, the so-called MT plus-end-tracking proteins …
Organization of microtubule plus-end dynamics by phase separation in mitosis.
Yang F, Ding M, Song X, Chen F, Yang T, Wang C, Hu C, Hu Q, Yao Y, Du S, Yao PY, Xia P, Adams G Jr, Fu C, Xiang S, Liu D, Wang Z, Yuan K, Liu X. Yang F, et al. J Mol Cell Biol. 2024 Jul 29;16(2):mjae006. doi: 10.1093/jmcb/mjae006. J Mol Cell Biol. 2024. PMID: 38323478 Free PMC article.
In eukaryotes, microtubule polymers are essential for cellular plasticity and fate decisions. End-binding (EB) proteins serve as scaffolds for orchestrating microtubule polymer dynamics and are essential for cellular dynamics and chromosome segregation in mitosis. H …
In eukaryotes, microtubule polymers are essential for cellular plasticity and fate decisions. End-binding (EB) proteins serve as scaf …
Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule-actin crosstalk during neurodevelopment.
Mun DJ, Goo BS, Suh BK, Hong JH, Woo Y, Kim SJ, Kim S, Lee SB, Won Y, Yoo JY, Cho E, Jang EJ, Nhung TTM, Triet HM, An H, Lee H, Nguyen MD, Park SY, Baek ST, Park SK. Mun DJ, et al. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2214507120. doi: 10.1073/pnas.2214507120. Epub 2023 Feb 16. Proc Natl Acad Sci U S A. 2023. PMID: 36795749 Free PMC article.
Regulation of microtubule dynamics is required to properly control various steps of neurodevelopment. In this study, we identified granule cell antiserum-positive 14 (Gcap14) as a microtubule plus-end-tracking protein and as a regulator of microtubu …
Regulation of microtubule dynamics is required to properly control various steps of neurodevelopment. In this study, we identified gr …
1,637 results