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275 results

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Page 1
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.
Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. Gate D, et al. Nature. 2020 Jan;577(7790):399-404. doi: 10.1038/s41586-019-1895-7. Epub 2020 Jan 8. Nature. 2020. PMID: 31915375 Free PMC article.
Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with Alzheimer's disease to two separate Epstein-Barr virus antigens. These results reveal an adaptive immune resp …
Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal …
Virus and cell RNAs expressed during Epstein-Barr virus replication.
Yuan J, Cahir-McFarland E, Zhao B, Kieff E. Yuan J, et al. J Virol. 2006 Mar;80(5):2548-65. doi: 10.1128/JVI.80.5.2548-2565.2006. J Virol. 2006. PMID: 16474161 Free PMC article.
Changes in Epstein-Barr virus (EBV) and cell RNA levels were assayed following immunoglobulin G (IgG) cross-linking-induced replication in latency 1-infected Akata Burkitt B lymphoblasts. ...Thus, LTIII expression is a characteristic of late EBV replication in both B lymph …
Changes in Epstein-Barr virus (EBV) and cell RNA levels were assayed following immunoglobulin G (IgG) cross-linking-induced replicati …
Epstein-Barr Virus-Specific Humoral Immune Responses in Health and Disease.
Middeldorp JM. Middeldorp JM. Curr Top Microbiol Immunol. 2015;391:289-323. doi: 10.1007/978-3-319-22834-1_10. Curr Top Microbiol Immunol. 2015. PMID: 26428379 Review.
Epstein-Barr virus (EBV) is widely distributed in the world and associated with a still increasing number of acute, chronic, malignant and autoimmune disease syndromes. ...
Epstein-Barr virus (EBV) is widely distributed in the world and associated with a still increasing number of acute, chronic, malignan …
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release.
Chao TY, Cheng YY, Wang ZY, Fang TF, Chang YR, Fuh CS, Su MT, Su YW, Hsu PH, Su YC, Chang YC, Lee TY, Chou WH, Middeldorp JM, Saraste J, Chen MR. Chao TY, et al. Microbiol Spectr. 2023 Feb 14;11(1):e0436922. doi: 10.1128/spectrum.04369-22. Epub 2023 Jan 5. Microbiol Spectr. 2023. PMID: 36602343 Free PMC article.
Epstein-Barr virus (EBV) replicates its genome in the nucleus and undergoes tegumentation and envelopment in the cytoplasm. ...IMPORTANCE Upon EBV lytic reactivation, the virus-encoded DNA replication machinery functions in the nucleus, while the newly synthesized D …
Epstein-Barr virus (EBV) replicates its genome in the nucleus and undergoes tegumentation and envelopment in the cytoplasm. ...IMPORT …
Epstein-Barr Virus (EBV)-Specific Humoral Immune Responses in Health and Disease.
Mautner J, Middeldorp JM. Mautner J, et al. Curr Top Microbiol Immunol. 2025 Jun 11. doi: 10.1007/82_2025_302. Online ahead of print. Curr Top Microbiol Immunol. 2025. PMID: 40495085
Epstein-Barr virus (EBV) infection has been associated with an expanding range of acute inflammatory, malignant, and autoimmune disorders. ...This chapter seeks to provide a comprehensive overview of the humoral immune response to EBV in healthy virus carriers and p …
Epstein-Barr virus (EBV) infection has been associated with an expanding range of acute inflammatory, malignant, and autoimmune disor …
Epidemiology of Epstein-Barr virus infection and infectious mononucleosis in the United Kingdom.
Kuri A, Jacobs BM, Vickaryous N, Pakpoor J, Middeldorp J, Giovannoni G, Dobson R. Kuri A, et al. BMC Public Health. 2020 Jun 12;20(1):912. doi: 10.1186/s12889-020-09049-x. BMC Public Health. 2020. PMID: 32532296 Free PMC article.
BACKGROUND: Epstein-Barr Virus (EBV) is a ubiquitous gamma-herpesvirus with which ~ 95% of the healthy population is infected. ...
BACKGROUND: Epstein-Barr Virus (EBV) is a ubiquitous gamma-herpesvirus with which ~ 95% of the healthy population is infected. ...
Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA.
Correia S, Palser A, Elgueta Karstegl C, Middeldorp JM, Ramayanti O, Cohen JI, Hildesheim A, Fellner MD, Wiels J, White RE, Kellam P, Farrell PJ. Correia S, et al. J Virol. 2017 Jul 12;91(15):e00375-17. doi: 10.1128/JVI.00375-17. Print 2017 Aug 1. J Virol. 2017. PMID: 28515295 Free PMC article.
Viral gene sequences from an enlarged set of about 200 Epstein-Barr virus (EBV) strains, including many primary isolates, have been used to investigate variation in key viral genetic regions, particularly LMP1, Zp, gp350, EBNA1, and the BART microRNA (miRNA) cluster 2. ...
Viral gene sequences from an enlarged set of about 200 Epstein-Barr virus (EBV) strains, including many primary isolates, have been u …
BamHI-A rightward frame 1, an Epstein-Barr virus-encoded oncogene and immune modulator.
Hoebe EK, Le Large TY, Greijer AE, Middeldorp JM. Hoebe EK, et al. Rev Med Virol. 2013 Nov;23(6):367-83. doi: 10.1002/rmv.1758. Epub 2013 Aug 31. Rev Med Virol. 2013. PMID: 23996634 Free PMC article. Review.
Epstein-Barr virus (EBV) causes several benign and malignant disorders of lymphoid and epithelial origin. ...
Epstein-Barr virus (EBV) causes several benign and malignant disorders of lymphoid and epithelial origin. ...
Association Between Antibodies That Bind Epstein-Barr Virus (EBV) gp350 and gH/gL and Shedding of EBV in Saliva From Nasopharyngeal Carcinoma Multiplex Family Members in Taiwan.
Liu KL, Hsu WL, Bu W, Yu KJ, Wang CP, Chien YC, Chen TC, Chen CJ, Hildesheim A, Middeldorp JM, Waterboer T, Cohen JI, Coghill AE, Liu Z. Liu KL, et al. Open Forum Infect Dis. 2024 Aug 31;11(9):ofae464. doi: 10.1093/ofid/ofae464. eCollection 2024 Sep. Open Forum Infect Dis. 2024. PMID: 39229285 Free PMC article.
Elevated levels of Epstein-Barr virus (EBV) gp350 and gH/gL antibodies have been associated with a lower risk of developing nasopharyngeal carcinoma (NPC), although the evidence remains inconclusive and unexplained. ...These findings underscore the complexity of virus …
Elevated levels of Epstein-Barr virus (EBV) gp350 and gH/gL antibodies have been associated with a lower risk of developing nasophary …
275 results