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267 results

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Page 1
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.
Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. Gate D, et al. Nature. 2020 Jan;577(7790):399-404. doi: 10.1038/s41586-019-1895-7. Epub 2020 Jan 8. Nature. 2020. PMID: 31915375 Free PMC article.
Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with Alzheimer's disease to two separate Epstein-Barr virus antigens. These results reveal an adaptive immune resp …
Finally, we used machine learning, cloning and peptide screens to demonstrate the specificity of clonally expanded TCRs in the cerebrospinal …
Epstein-Barr Virus-Specific Humoral Immune Responses in Health and Disease.
Middeldorp JM. Middeldorp JM. Curr Top Microbiol Immunol. 2015;391:289-323. doi: 10.1007/978-3-319-22834-1_10. Curr Top Microbiol Immunol. 2015. PMID: 26428379 Review.
Epstein-Barr virus (EBV) is widely distributed in the world and associated with a still increasing number of acute, chronic, malignant and autoimmune disease syndromes. ...
Epstein-Barr virus (EBV) is widely distributed in the world and associated with a still increasing number of acute, chronic, malignan …
Virus and cell RNAs expressed during Epstein-Barr virus replication.
Yuan J, Cahir-McFarland E, Zhao B, Kieff E. Yuan J, et al. J Virol. 2006 Mar;80(5):2548-65. doi: 10.1128/JVI.80.5.2548-2565.2006. J Virol. 2006. PMID: 16474161 Free PMC article.
Changes in Epstein-Barr virus (EBV) and cell RNA levels were assayed following immunoglobulin G (IgG) cross-linking-induced replication in latency 1-infected Akata Burkitt B lymphoblasts. ...Thus, LTIII expression is a characteristic of late EBV replication in both B lymph …
Changes in Epstein-Barr virus (EBV) and cell RNA levels were assayed following immunoglobulin G (IgG) cross-linking-induced replicati …
2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19.
Schulman S, Arnold DM, Bradbury CA, Broxmeyer L, Connors JM, Falanga A, Iba T, Kaatz S, Levy JH, Middeldorp S, Minichiello T, Nazy I, Ramacciotti E, Resnick HE, Samama CM, Sholzberg M, Thachil J, Zarychanski R, Spyropoulos AC; International Society on Thrombosis and Haemostasis. Schulman S, et al. J Thromb Haemost. 2024 Jun;22(6):1779-1797. doi: 10.1016/j.jtha.2024.02.011. Epub 2024 Mar 18. J Thromb Haemost. 2024. PMID: 38503600 Free article.
Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis.
Meier UC, Cipian RC, Karimi A, Ramasamy R, Middeldorp JM. Meier UC, et al. Front Immunol. 2021 Nov 1;12:757302. doi: 10.3389/fimmu.2021.757302. eCollection 2021. Front Immunol. 2021. PMID: 34790199 Free PMC article.
Roles for viral infections and aberrant immune responses in driving localized neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of intense research. Epstein-Barr virus (EBV), as a persistent and frequently reactivating virus with major …
Roles for viral infections and aberrant immune responses in driving localized neuroinflammation and neurodegeneration in multiple sclerosis …
Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release.
Chao TY, Cheng YY, Wang ZY, Fang TF, Chang YR, Fuh CS, Su MT, Su YW, Hsu PH, Su YC, Chang YC, Lee TY, Chou WH, Middeldorp JM, Saraste J, Chen MR. Chao TY, et al. Microbiol Spectr. 2023 Feb 14;11(1):e0436922. doi: 10.1128/spectrum.04369-22. Epub 2023 Jan 5. Microbiol Spectr. 2023. PMID: 36602343 Free PMC article.
Epstein-Barr virus (EBV) replicates its genome in the nucleus and undergoes tegumentation and envelopment in the cytoplasm. ...IMPORTANCE Upon EBV lytic reactivation, the virus-encoded DNA replication machinery functions in the nucleus, while the newly synthesized D …
Epstein-Barr virus (EBV) replicates its genome in the nucleus and undergoes tegumentation and envelopment in the cytoplasm. ...IMPORT …
BamHI-A rightward frame 1, an Epstein-Barr virus-encoded oncogene and immune modulator.
Hoebe EK, Le Large TY, Greijer AE, Middeldorp JM. Hoebe EK, et al. Rev Med Virol. 2013 Nov;23(6):367-83. doi: 10.1002/rmv.1758. Epub 2013 Aug 31. Rev Med Virol. 2013. PMID: 23996634 Free PMC article. Review.
Epstein-Barr virus (EBV) causes several benign and malignant disorders of lymphoid and epithelial origin. ...
Epstein-Barr virus (EBV) causes several benign and malignant disorders of lymphoid and epithelial origin. ...
SARS-CoV-2 infection as a cause of neurodegeneration.
Bonhenry D, Charnley M, Gonçalves J, Hammarström P, Heneka MT, Itzhaki R, Lambert JC, Mannan M, Baig AM, Middeldorp J, Nyström S, Reynolds NP, Stefanatou M, Berryman JT. Bonhenry D, et al. Lancet Neurol. 2024 Jun;23(6):562-563. doi: 10.1016/S1474-4422(24)00178-9. Lancet Neurol. 2024. PMID: 38760096 No abstract available.
Association Between Antibodies That Bind Epstein-Barr Virus (EBV) gp350 and gH/gL and Shedding of EBV in Saliva From Nasopharyngeal Carcinoma Multiplex Family Members in Taiwan.
Liu KL, Hsu WL, Bu W, Yu KJ, Wang CP, Chien YC, Chen TC, Chen CJ, Hildesheim A, Middeldorp JM, Waterboer T, Cohen JI, Coghill AE, Liu Z. Liu KL, et al. Open Forum Infect Dis. 2024 Aug 31;11(9):ofae464. doi: 10.1093/ofid/ofae464. eCollection 2024 Sep. Open Forum Infect Dis. 2024. PMID: 39229285 Free PMC article.
Elevated levels of Epstein-Barr virus (EBV) gp350 and gH/gL antibodies have been associated with a lower risk of developing nasopharyngeal carcinoma (NPC), although the evidence remains inconclusive and unexplained. ...These findings underscore the complexity of virus
Elevated levels of Epstein-Barr virus (EBV) gp350 and gH/gL antibodies have been associated with a lower risk of developing nasophary …
Epidemiology of Epstein-Barr virus infection and infectious mononucleosis in the United Kingdom.
Kuri A, Jacobs BM, Vickaryous N, Pakpoor J, Middeldorp J, Giovannoni G, Dobson R. Kuri A, et al. BMC Public Health. 2020 Jun 12;20(1):912. doi: 10.1186/s12889-020-09049-x. BMC Public Health. 2020. PMID: 32532296 Free PMC article.
BACKGROUND: Epstein-Barr Virus (EBV) is a ubiquitous gamma-herpesvirus with which ~ 95% of the healthy population is infected. ...
BACKGROUND: Epstein-Barr Virus (EBV) is a ubiquitous gamma-herpesvirus with which ~ 95% of the healthy population is infected. ...
267 results