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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1979 1
1981 2
1984 2
1987 2
1992 1
1993 2
1995 2
1997 1
1998 2
2001 3
2002 1
2003 2
2004 1
2005 3
2006 5
2007 3
2008 5
2009 6
2010 1
2011 5
2012 5
2013 3
2014 6
2015 6
2016 10
2017 8
2018 7
2019 4
2020 7
2021 5
2022 7
2023 4

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108 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit (MIDAS): an international randomised clinical trial.
Santer P, Anstey MH, Patrocínio MD, Wibrow B, Teja B, Shay D, Shaefi S, Parsons CS, Houle TT, Eikermann M; MIDAS Study Group. Santer P, et al. Intensive Care Med. 2020 Oct;46(10):1884-1893. doi: 10.1007/s00134-020-06216-x. Epub 2020 Sep 3. Intensive Care Med. 2020. PMID: 32885276 Free PMC article. Clinical Trial.
Time to vasopressor discontinuation was not different between midodrine and placebo groups (median [IQR], 23.5 [10-54] vs 22.5 [10.4-40] h; difference, 1 h; 95% CI - 10.4 to 12.3 h; p = 0.62). No differences in secondary endpoints were observed. Bradycardia occurred more o …
Time to vasopressor discontinuation was not different between midodrine and placebo groups (median [IQR], 23.5 [10-54] vs 22.5 [10.4- …
Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial.
Cavallin M, Kamath PS, Merli M, Fasolato S, Toniutto P, Salerno F, Bernardi M, Romanelli RG, Colletta C, Salinas F, Di Giacomo A, Ridola L, Fornasiere E, Caraceni P, Morando F, Piano S, Gatta A, Angeli P; Italian Association for the Study of the Liver Study Group on Hepatorenal Syndrome. Cavallin M, et al. Hepatology. 2015 Aug;62(2):567-74. doi: 10.1002/hep.27709. Epub 2015 Feb 13. Hepatology. 2015. PMID: 25644760 Free article. Clinical Trial.
Where terlipressin is not available, as in the United States, midodrine and octreotide with albumin are used as an alternative treatment of HRS. ...CONCLUSION: Terlipressin plus albumin is significantly more effective than midodrine and octreotide plus albumin in im …
Where terlipressin is not available, as in the United States, midodrine and octreotide with albumin are used as an alternative treatm …
Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial.
Solà E, Solé C, Simón-Talero M, Martín-Llahí M, Castellote J, Garcia-Martínez R, Moreira R, Torrens M, Márquez F, Fabrellas N, de Prada G, Huelin P, Lopez Benaiges E, Ventura M, Manríquez M, Nazar A, Ariza X, Suñé P, Graupera I, Pose E, Colmenero J, Pavesi M, Guevara M, Navasa M, Xiol X, Córdoba J, Vargas V, Ginès P. Solà E, et al. J Hepatol. 2018 Dec;69(6):1250-1259. doi: 10.1016/j.jhep.2018.08.006. Epub 2018 Aug 21. J Hepatol. 2018. PMID: 30138685 Clinical Trial.
The aim of this study was to investigate whether treatment with midodrine, an alpha-adrenergic vasoconstrictor, together with intravenous albumin improves circulatory dysfunction and prevents complications of cirrhosis in patients awaiting LT. ...This study was aimed at in …
The aim of this study was to investigate whether treatment with midodrine, an alpha-adrenergic vasoconstrictor, together with intrave …
Midodrine for the Prevention of Vasovagal Syncope : A Randomized Clinical Trial.
Sheldon R, Faris P, Tang A, Ayala-Paredes F, Guzman J, Marquez M, Morillo CA, Krahn AD, Kus T, Ritchie D, Safdar S, Maxey C, Raj SR; POST 4 investigators. Sheldon R, et al. Ann Intern Med. 2021 Oct;174(10):1349-1356. doi: 10.7326/M20-5415. Epub 2021 Aug 3. Ann Intern Med. 2021. PMID: 34339231 Clinical Trial.
OBJECTIVE: To determine whether midodrine can prevent vasovagal syncope in usual clinical conditions. ...Compared with patients receiving placebo, fewer patients receiving midodrine had at least 1 syncope episode (28 of 66 [42%] vs. 41 of 67 [61%]). ...
OBJECTIVE: To determine whether midodrine can prevent vasovagal syncope in usual clinical conditions. ...Compared with patients recei …
A pilot, feasibility, randomised controlled trial of midodrine as adjunctive vasopressor for low-dose vasopressor-dependent hypotension in intensive care patients: The MAVERIC study.
Costa-Pinto R, Yong ZT, Yanase F, Young C, Brown A, Udy A, Young PJ, Eastwood G, Bellomo R. Costa-Pinto R, et al. J Crit Care. 2022 Feb;67:166-171. doi: 10.1016/j.jcrc.2021.11.004. Epub 2021 Nov 18. J Crit Care. 2022. PMID: 34801917 Clinical Trial.
RESULTS: We screened 381 patients over 22-months and enrolled 62 (32 in midodrine group, 30 in usual care group). Median time to cessation of vasopressor infusion was 16.5 h for midodrine vs 19 h for usual care (p = 0.22). ...Protocol compliance was 96.9%. One patie …
RESULTS: We screened 381 patients over 22-months and enrolled 62 (32 in midodrine group, 30 in usual care group). Median time to cess …
Effects of midodrine in patients with ascites due to cirrhosis: Systematic review and meta-analysis.
Guo TT, Yang Y, Song Y, Ren Y, Liu ZX, Cheng G. Guo TT, et al. J Dig Dis. 2016 Jan;17(1):11-9. doi: 10.1111/1751-2980.12304. J Dig Dis. 2016. PMID: 26630543 Review.
OBJECTIVE: Midodrine has been reported to improve systemic and renal hemodynamics in patients with cirrhotic ascites. ...When midodrine was used as an alternative to albumin in large-volume paracentesis, the mortality was higher for midodrine than for albumin …
OBJECTIVE: Midodrine has been reported to improve systemic and renal hemodynamics in patients with cirrhotic ascites. ...When mido
Midodrine for orthostatic hypotension: a systematic review and meta-analysis of clinical trials.
Parsaik AK, Singh B, Altayar O, Mascarenhas SS, Singh SK, Erwin PJ, Murad MH. Parsaik AK, et al. J Gen Intern Med. 2013 Nov;28(11):1496-503. doi: 10.1007/s11606-013-2520-3. Epub 2013 Jun 18. J Gen Intern Med. 2013. PMID: 23775146 Free PMC article. Review.
OBJECTIVE: To perform a systematic review and meta-analysis of clinical trials evaluating the efficacy and safety of midodrine in orthostatic hypotension (OH). METHODS: We searched major databases and related conference proceedings through June 30, 2012. ...CONCLUSION: The …
OBJECTIVE: To perform a systematic review and meta-analysis of clinical trials evaluating the efficacy and safety of midodrine in ort …
Midodrine for the prevention of vasovagal syncope: a systematic review and meta-analysis.
Lei LY, Raj SR, Sheldon RS. Lei LY, et al. Europace. 2022 Jul 21;24(7):1171-1178. doi: 10.1093/europace/euab323. Europace. 2022. PMID: 35025999 Free PMC article.
To evaluate the efficacy of midodrine to prevent syncope in patients with recurrent VVS by conducting a systematic review and meta-analysis of published studies. ...The two rigorous double-blind, randomized, placebo-controlled clinical trials included 179 VVS patients with …
To evaluate the efficacy of midodrine to prevent syncope in patients with recurrent VVS by conducting a systematic review and meta-an …
Terlipressin and the Treatment of Hepatorenal Syndrome: How the CONFIRM Trial Moves the Story Forward.
Belcher JM, Parada XV, Simonetto DA, Juncos LA, Karakala N, Wadei HM, Sharma P, Regner KR, Nadim MK, Garcia-Tsao G, Velez JCQ, Parikh SM, Chung RT, Allegretti AS; HRS-HARMONY Study Investigators. Belcher JM, et al. Am J Kidney Dis. 2022 May;79(5):737-745. doi: 10.1053/j.ajkd.2021.08.016. Epub 2021 Oct 2. Am J Kidney Dis. 2022. PMID: 34606933 Clinical Trial.
Midodrine improves clinical and economic outcomes in patients with septic shock: a randomized controlled clinical trial.
Adly DHE, Bazan NS, El Borolossy RM, Anan IF, Fakher MA, El Wakeel LM. Adly DHE, et al. Ir J Med Sci. 2022 Dec;191(6):2785-2795. doi: 10.1007/s11845-021-02903-w. Epub 2022 Jan 3. Ir J Med Sci. 2022. PMID: 34981420 Clinical Trial.
Participants were randomized into two groups: norepinephrine (IV norepinephrine) and midodrine (IV norepinephrine + oral midodrine 10 mg thrice a day). ...The midodrine group showed cost-saving results versus the norepinephrine group. ...
Participants were randomized into two groups: norepinephrine (IV norepinephrine) and midodrine (IV norepinephrine + oral midodrine
108 results