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Pathophysiology and management of postural orthostatic tachycardia syndrome (POTS): A literature review.
Ghazal M, Akkawi AR, Fancher A, Oundo E, Tanzeem H, Sajjad L, Briasoulis A. Ghazal M, et al. Curr Probl Cardiol. 2025 Mar;50(3):102977. doi: 10.1016/j.cpcardiol.2024.102977. Epub 2024 Dec 18. Curr Probl Cardiol. 2025. PMID: 39706392 Review.
Neuropathic POTS, resulting from impaired vasoconstriction during orthostatic stress, responds to agents that enhance vascular tone, such as pyridostigmine and midodrine. Hypovolemic POTS, often triggered by dehydration and physical deconditioning, respond pr …
Neuropathic POTS, resulting from impaired vasoconstriction during orthostatic stress, responds to agents that enhance vascular tone, …
Dysautonomia: a common comorbidity of systemic disease.
Blitshteyn S. Blitshteyn S. Immunol Res. 2025 Jul 8;73(1):105. doi: 10.1007/s12026-025-09661-2. Immunol Res. 2025. PMID: 40624434 Free PMC article. Review.
The most common autonomic disorders encountered in clinical practice are postural orthostatic tachycardia syndrome (POTS), neurocardiogenic syncope (NCS), and orthostatic hypotension (OH), which may be undiagnosed or often mislabeled with psychiatric disorders. ...Treatmen …
The most common autonomic disorders encountered in clinical practice are postural orthostatic tachycardia syndrome (POTS), neurocardi …
Dysautonomia: A Forgotten Condition - Part 1.
Rocha EA, Mehta N, Távora-Mehta MZP, Roncari CF, Cidrão AAL, Elias Neto J. Rocha EA, et al. Arq Bras Cardiol. 2021 Apr;116(4):814-835. doi: 10.36660/abc.20200420. Arq Bras Cardiol. 2021. PMID: 33886735 Free PMC article. English, Portuguese.
They are classified as Reflex Syndromes, Postural Orthostatic Tachycardia Syndrome (POTS), Chronic Fatigue Syndrome, Neurogenic Orthostatic Hypotension (nOH) and Carotid Sinus Hypersensitivity Syndrome. ...They are classified as Reflex Syndromes, Postural Orthostatic Tachy …
They are classified as Reflex Syndromes, Postural Orthostatic Tachycardia Syndrome (POTS), Chronic Fatigue Syndrome, Neurogenic Ortho …
The evidence for treatments for postural orthostatic tachycardia syndrome: a systematic review of randomized trials.
Kwok CS, Lee S, Hall M, Qureshi AI, Lip GYH, Loke YK, Raj SR, Holroyd E. Kwok CS, et al. Trends Cardiovasc Med. 2025 Nov;35(8):517-527. doi: 10.1016/j.tcm.2025.07.001. Epub 2025 Jul 11. Trends Cardiovasc Med. 2025. PMID: 40653179
The limited systematic reviews evaluating the treatment for POTS only reported three or fewer trials when many more trials have been published. In this systematic review, we evaluate the evidence for different treatments for POTS from 21 randomized clinical trials w …
The limited systematic reviews evaluating the treatment for POTS only reported three or fewer trials when many more trials have been …
[Postural tachycardia syndrome (PoTS): An up-to-date].
Astudillo L, Laure A, Fabry V, Pugnet G, Maury P, Labrunée M, Sailler L, Pavy-Le Traon A. Astudillo L, et al. Rev Med Interne. 2018 Aug;39(8):627-634. doi: 10.1016/j.revmed.2018.04.017. Epub 2018 Jun 13. Rev Med Interne. 2018. PMID: 29909001 Review. French.
Postural tachycardia syndrome (PoTS) is a multifactorial syndrome defined by an increase in heart rate 30bpm, within 10minutes of standing (or during a head up tilt test to at least 60 ), in absence of orthostatic hypotension. ...The treatment is based on nonpharmacologic …
Postural tachycardia syndrome (PoTS) is a multifactorial syndrome defined by an increase in heart rate 30bpm, within 10minutes of st …
Systematic literature review: treatment of postural orthostatic tachycardia syndrome (POTS).
Schiweck N, Langer K, Maier A, Vilser D, Spiegler J. Schiweck N, et al. Clin Auton Res. 2026 Feb;36(1):3-16. doi: 10.1007/s10286-025-01172-2. Epub 2025 Nov 12. Clin Auton Res. 2026. PMID: 41225175 Free PMC article. Review.
In children, a sustained HR increment of at least 40 bpm is required for diagnosis of POTS. POTS is a common condition in adults and children suffering from myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). ...There are single studies which imply that …
In children, a sustained HR increment of at least 40 bpm is required for diagnosis of POTS. POTS is a common condition in adul …
Clinical neurophysiology of postural tachycardia syndrome.
Cutsforth-Gregory JK, Sandroni P. Cutsforth-Gregory JK, et al. Handb Clin Neurol. 2019;161:429-445. doi: 10.1016/B978-0-444-64142-7.00066-7. Handb Clin Neurol. 2019. PMID: 31307619 Review.
Patients with suspected POTS should undergo comprehensive cardiac and neurologic examinations and autonomic and laboratory tests to determine the most likely pathophysiologic basis of OI. The objectives of POTS management are to (1) increase the time that patients c …
Patients with suspected POTS should undergo comprehensive cardiac and neurologic examinations and autonomic and laboratory tests to d …
Difference between supine and upright blood pressure associates to the efficacy of midodrine on postural orthostatic tachycardia syndrome (POTS) in children.
Deng W, Liu Y, Liu AD, Holmberg L, Ochs T, Li X, Yang J, Tang C, Du J, Jin H. Deng W, et al. Pediatr Cardiol. 2014 Apr;35(4):719-25. doi: 10.1007/s00246-013-0843-9. Epub 2013 Nov 20. Pediatr Cardiol. 2014. PMID: 24253613
The study was designed to examine the therapeutic efficacy of midodrine hydrochloride by quantifying changes in blood pressure during the head-up test (HUT), in children with POTS. ...Hence, the results suggested that looking at the changes in blood pressure during …
The study was designed to examine the therapeutic efficacy of midodrine hydrochloride by quantifying changes in blood pressure during …
Approach to Postural Orthostatic Tachycardia Syndrome.
Robbins NM, Golden EP, Freeman KC, Bhavaraju-Sanka RK, Snapper H, Cook GA. Robbins NM, et al. Neurol Clin Pract. 2026 Jun;16(3):e200620. doi: 10.1212/CPJ.0000000000200620. Epub 2026 Apr 28. Neurol Clin Pract. 2026. PMID: 42114076 Review.
Several safe and effective medication options are also available, such as propranolol and midodrine. Several comorbidities are common, such as migraine and neurocardiogenic syncope, and should be screened for and treated rather than attributed out-of-hand to POTS. S …
Several safe and effective medication options are also available, such as propranolol and midodrine. Several comorbidities are common …
Plasma copeptin and therapeutic effectiveness of midodrine hydrochloride on postural tachycardia syndrome in children.
Zhao J, Tang C, Jin H, Du J. Zhao J, et al. J Pediatr. 2014 Aug;165(2):290-294.e1. doi: 10.1016/j.jpeds.2014.04.032. Epub 2014 May 22. J Pediatr. 2014. PMID: 24857518
OBJECTIVES: Midodrine hydrochloride is used clinically to treat children with postural tachycardia syndrome (POTS), but it is not effective in all patients. ...The group with POTS received midodrine hydrochloride treatment for 1.5-3 months. The plasma …
OBJECTIVES: Midodrine hydrochloride is used clinically to treat children with postural tachycardia syndrome (POTS), but it is …
43 results