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Page 1
Migraine Aura Without Headache [corrected].
Shah DR, Dilwali S, Friedman DI. Shah DR, et al. Curr Pain Headache Rep. 2018 Sep 17;22(11):77. doi: 10.1007/s11916-018-0725-1. Curr Pain Headache Rep. 2018. PMID: 30225597 Review.
RECENT FINDINGS: Typical aura without headache is a known entity within the spectrum of migraine. Its pathophysiology is suggested to be similar to classic migraines, with cortical spreading depression leading to aura formation but withou …
RECENT FINDINGS: Typical aura without headache is a known entity within the spectrum of migraine. Its pathophysiology is sugge …
A Phase-by-Phase Review of Migraine Pathophysiology.
Dodick DW. Dodick DW. Headache. 2018 May;58 Suppl 1:4-16. doi: 10.1111/head.13300. Headache. 2018. PMID: 29697154 Review.
Migraine is a common, disabling neurological disorder characterized by multiple phases: premonitory, aura, headache, postdrome, and interictal. ...The headache phase involves activation of the trigeminovascular system, a pathway that is well characterized. In one-th …
Migraine is a common, disabling neurological disorder characterized by multiple phases: premonitory, aura, headache, postdrome …
Migraine with aura.
Lucas C. Lucas C. Rev Neurol (Paris). 2021 Sep;177(7):779-784. doi: 10.1016/j.neurol.2021.07.010. Epub 2021 Aug 9. Rev Neurol (Paris). 2021. PMID: 34384631 Review.
The pivotal role of cortical spreading depression (CSD) as a mechanism underlying aura has been widely supported by a large body of studies. ...The prophylactic treatments for migraine with aura are those used in migraine wi …
The pivotal role of cortical spreading depression (CSD) as a mechanism underlying aura has been widely supported …
Genetics of migraine: where are we now?
Grangeon L, Lange KS, Waliszewska-Prosół M, Onan D, Marschollek K, Wiels W, Mikulenka P, Farham F, Gollion C, Ducros A; European Headache Federation School of Advanced Studies (EHF-SAS). Grangeon L, et al. J Headache Pain. 2023 Feb 20;24(1):12. doi: 10.1186/s10194-023-01547-8. J Headache Pain. 2023. PMID: 36800925 Free PMC article. Review.
In monogenic migraines, including familial hemiplegic migraine and migraine with aura associated with hereditary small-vessel disorders, the identified genes code for proteins expressed in neurons, glial cells, or vessels, all of which increase suscept …
In monogenic migraines, including familial hemiplegic migraine and migraine with aura associated with hereditary …
Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain.
Noseda R, Burstein R. Noseda R, et al. Pain. 2013 Dec;154 Suppl 1:S44-53. doi: 10.1016/j.pain.2013.07.021. Epub 2013 Jul 25. Pain. 2013. PMID: 23891892 Review.
Data supporting the activation and sensitization of the trigeminovascular system include the progressive development of cephalic and whole-body cutaneous allodynia during a migraine attack. In addition, structural and functional alterations include the presence of subcorti …
Data supporting the activation and sensitization of the trigeminovascular system include the progressive development of cephalic and whole-b …
Hemiplegic Migraine.
Nandyala A, Shah T, Ailani J. Nandyala A, et al. Curr Neurol Neurosci Rep. 2023 Jul;23(7):381-387. doi: 10.1007/s11910-023-01277-z. Epub 2023 May 29. Curr Neurol Neurosci Rep. 2023. PMID: 37247170 Review.
Hemiplegic migraine is a severe subset of migraine with aura with symptoms including reversible hemiparesis in addition to other aura symptoms such as visual, sensory, or speech. The exact pathophysiology of hemiplegic migraine is not cle …
Hemiplegic migraine is a severe subset of migraine with aura with symptoms including reversible hemiparesis in a …
Migraine Aura: Pathophysiology, Mimics, and Treatment Options.
Fraser CL, Hepschke JL, Jenkins B, Prasad S. Fraser CL, et al. Semin Neurol. 2019 Dec;39(6):739-748. doi: 10.1055/s-0039-1700525. Epub 2019 Dec 17. Semin Neurol. 2019. PMID: 31847045 Review.
Marked efflux of cellular potassium and glutamate contributes to the cortical spreading depression that forms the electrophysiological basis of migraine aura phenomena. ...Before diagnosing a patient with migraine aura, it i …
Marked efflux of cellular potassium and glutamate contributes to the cortical spreading depression that forms the elect …
Therapeutic implications of cortical spreading depression models in migraine.
Takizawa T, Ayata C, Chen SP. Takizawa T, et al. Prog Brain Res. 2020;255:29-67. doi: 10.1016/bs.pbr.2020.05.009. Epub 2020 Jun 27. Prog Brain Res. 2020. PMID: 33008510 Review.
Migraine is among the most common and disabling neurological diseases in the world. Cortical spreading depression (CSD) is a wave of near-complete depolarization of neurons and glial cells that slowly propagates along the cortex creating the perception …
Migraine is among the most common and disabling neurological diseases in the world. Cortical spreading depression …
History of migraine with aura and cortical spreading depression from 1941 and onwards.
Tfelt-Hansen PC. Tfelt-Hansen PC. Cephalalgia. 2010 Jul;30(7):780-92. doi: 10.1111/j.1468-2982.2009.02015.x. Cephalalgia. 2010. PMID: 19740119 Review.
Leao described cortical spreading depression (CSD) in rabbits in 1944 and noticed its similarity to the migraine aura. Despite these scattered pieces of evidence, the prevailing theory was that the migraine aura was caused by a vas …
Leao described cortical spreading depression (CSD) in rabbits in 1944 and noticed its similarity to the migraine …
Rethinking migraine with aura: Why cortical spreading depolarization (depression), not aura, causes headaches.
Moskowitz MA. Moskowitz MA. Cephalalgia. 2025 Sep;45(9):3331024251370629. doi: 10.1177/03331024251370629. Epub 2025 Sep 2. Cephalalgia. 2025. PMID: 40891631 Free article.
Cortical spreading depolarization (depression) underlies migrainous aura and is posited to cause its headache. ...Consistent with this notion, a first human case studied electrophysiologically showed that cortical spreading depolarization …
Cortical spreading depolarization (depression) underlies migrainous aura and is posited to cause its headache. . …
737 results