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125 results

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Filters applied: Clinical Trial, Randomized Controlled Trial, Systematic Review. Clear all
Page 1
Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases.
Rambaldi A, Jacobs BP, Gluud C. Rambaldi A, et al. Cochrane Database Syst Rev. 2007 Oct 17;2007(4):CD003620. doi: 10.1002/14651858.CD003620.pub3. Cochrane Database Syst Rev. 2007. PMID: 17943794 Free PMC article. Review.
Randomised clinical trials have assessed whether extracts of milk thistle, Silybum marianum (L) Gaertneri, have any effect in patients with alcoholic and/or hepatitis B or C virus liver diseases. OBJECTIVES: To assess the beneficial and harmful effects …
Randomised clinical trials have assessed whether extracts of milk thistle, Silybum marianum (L) Gaertneri, have …
Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases.
Rambaldi A, Jacobs BP, Iaquinto G, Gluud C. Rambaldi A, et al. Cochrane Database Syst Rev. 2005 Apr 18;(2):CD003620. doi: 10.1002/14651858.CD003620.pub2. Cochrane Database Syst Rev. 2005. Update in: Cochrane Database Syst Rev. 2007 Oct 17;(4):CD003620. doi: 10.1002/14651858.CD003620.pub3. PMID: 15846671 Updated. Review.
Randomised clinical trials have assessed whether extracts of milk thistle, Silybum marianum (L) Gaertneri, have any effect in patients with alcoholic and/or hepatitis B or C virus liver diseases. OBJECTIVES: To assess the beneficial and harmful effects …
Randomised clinical trials have assessed whether extracts of milk thistle, Silybum marianum (L) Gaertneri, have …
Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review.
Gillessen A, Schmidt HH. Gillessen A, et al. Adv Ther. 2020 Apr;37(4):1279-1301. doi: 10.1007/s12325-020-01251-y. Epub 2020 Feb 17. Adv Ther. 2020. PMID: 32065376 Free PMC article.
Silymarin, an extract from milk thistle seeds, has been used for centuries to treat hepatic conditions. Preclinical data indicate that silymarin can reduce oxidative stress and consequent cytotoxicity, thereby protecting intact liver cells or cells not yet irreversi …
Silymarin, an extract from milk thistle seeds, has been used for centuries to treat hepatic conditions. Preclinical data indic …
Milk thistle for the treatment of liver disease: a systematic review and meta-analysis.
Jacobs BP, Dennehy C, Ramirez G, Sapp J, Lawrence VA. Jacobs BP, et al. Am J Med. 2002 Oct 15;113(6):506-15. doi: 10.1016/s0002-9343(02)01244-5. Am J Med. 2002. PMID: 12427501 Review.
PURPOSE: Milk thistle, an herbal compound, is the dietary supplement taken most frequently by patients with chronic liver disease. ...The overall summary odds ratio for mortality in the milk thistle group compared with placebo was 0.8 (95% confidence i …
PURPOSE: Milk thistle, an herbal compound, is the dietary supplement taken most frequently by patients with chronic liver dise …
Silibinin as a major component of milk thistle seed provides promising influences against diabetes and its complications: a systematic review.
Zare Mehrjerdi P, Asadi S, Ehsani E, Askari VR, Baradaran Rahimi V. Zare Mehrjerdi P, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 Oct;397(10):7531-7549. doi: 10.1007/s00210-024-03172-x. Epub 2024 May 27. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38801454
Silibinin, or silybin, is a polyphenolic flavonoid and the main active component of silymarin, isolated from the seeds of the milk thistle plant (Silybum marianum). It has been shown to have antioxidant, antineoplastic, hepatoprotective, neuroprotectiv …
Silibinin, or silybin, is a polyphenolic flavonoid and the main active component of silymarin, isolated from the seeds of the milk
Silymarin (Milk Thistle) Treatment of Adults With Gambling Disorder: A Double-Blind, Placebo-Controlled Trial.
Grant JE, Driessens C, Chamberlain SR. Grant JE, et al. Clin Neuropharmacol. 2024 Mar-Apr 01;47(2):54-58. doi: 10.1097/WNF.0000000000000585. Clin Neuropharmacol. 2024. PMID: 38478366 Clinical Trial.
OBJECTIVE: Data on the pharmacological treatment of gambling disorder are limited. Silymarin (derived from milk thistle) has antioxidant properties. The goal of the current study was to determine the efficacy and tolerability of silymarin in adults with gambling dis …
OBJECTIVE: Data on the pharmacological treatment of gambling disorder are limited. Silymarin (derived from milk thistle) has a …
Milk Thistle Treatment for Children and Adults with Trichotillomania: A Double-Blind, Placebo-Controlled, Crossover Negative Study.
Grant JE, Redden SA, Chamberlain SR. Grant JE, et al. J Clin Psychopharmacol. 2019 Mar/Apr;39(2):129-134. doi: 10.1097/JCP.0000000000001005. J Clin Psychopharmacol. 2019. PMID: 30694881 Free PMC article. Clinical Trial.
METHODS: Twenty individuals (19 [95.0%] women; 16 adults; mean age, 27.9 [11.5] years) with trichotillomania entered a 12-week, double-blind, placebo-controlled crossover study (6 weeks of milk thistle and 6 weeks of placebo with a 1-week wash-out in between). Dosin …
METHODS: Twenty individuals (19 [95.0%] women; 16 adults; mean age, 27.9 [11.5] years) with trichotillomania entered a 12-week, double-blind …
Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
Calderon Martinez E, Herrera D, Mogan S, Hameed Z, Jangda AA, Khan TJ, Mroke P, Sajid S, Shah YR, Baig I. Calderon Martinez E, et al. Cureus. 2023 Oct 24;15(10):e47608. doi: 10.7759/cureus.47608. eCollection 2023 Oct. Cureus. 2023. PMID: 38021897 Free PMC article. Review.
Silymarin, extracted from milk thistle (Silybum marianum), is esteemed for its antioxidative, anti-inflammatory, and antifibrotic properties, notably within liver-related contexts. ...
Silymarin, extracted from milk thistle (Silybum marianum), is esteemed for its antioxidative, anti-inflammatory, …
Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis.
Li S, Duan F, Li S, Lu B. Li S, et al. Ann Hepatol. 2024 Mar-Apr;29(2):101174. doi: 10.1016/j.aohep.2023.101174. Epub 2023 Oct 29. Ann Hepatol. 2024. PMID: 38579127 Free article.
Silymarin is a hepatoprotective extract of milk thistle, but its efficacy in NAFLD remains unclear. MATERIALS AND METHODS: Relevant studies were searched in PubMed, Embase, the Cochrane Library, Web of Science, clinicaltrails.gov, and China National Knowledge Infras …
Silymarin is a hepatoprotective extract of milk thistle, but its efficacy in NAFLD remains unclear. MATERIALS AND METHODS: Rel …
Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial.
Navarro VJ, Belle SH, D'Amato M, Adfhal N, Brunt EM, Fried MW, Reddy KR, Wahed AS, Harrison S; Silymarin in NASH and C Hepatitis (SyNCH) Study Group. Navarro VJ, et al. PLoS One. 2019 Sep 19;14(9):e0221683. doi: 10.1371/journal.pone.0221683. eCollection 2019. PLoS One. 2019. PMID: 31536511 Free PMC article. Clinical Trial.
The botanical product silymarin, an extract of milk thistle, is commonly used by patients to treat chronic liver disease and may be a treatment for NASH due to its antioxidant properties. ...
The botanical product silymarin, an extract of milk thistle, is commonly used by patients to treat chronic liver disease and m …
125 results