Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 3
2004 3
2005 2
2006 4
2007 3
2008 2
2009 1
2010 6
2011 4
2012 2
2013 1
2014 4
2015 1
2016 2
2017 3
2018 2
2019 3
2020 3
2021 2
2022 5
2023 6
2024 2
2025 6
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

68 results

Results by year

Filters applied: . Clear all
Page 1
New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types.
Gampala S, Moon HR, Wireman R, Peil J, Kiran S, Mitchell DK, Brewster K, Mang H, Masters A, Bach C, Smith-Kinnamen W, Doud EH, Rai R, Mosley AL, Quinney SK, Clapp DW, Hamdouchi C, Wikel J, Zhang C, Han B, Georgiadis MM, Kelley MR, Fishel ML. Gampala S, et al. Among authors: georgiadis mm. Pharmacol Res. 2024 Mar;201:107092. doi: 10.1016/j.phrs.2024.107092. Epub 2024 Feb 2. Pharmacol Res. 2024. PMID: 38311014 Free PMC article.
Ref-1 is overexpressed in neovascular eye disease and targetable with a novel inhibitor.
Muniyandi A, Hartman GD, Sishtla K, Rai R, Gomes C, Day K, Song Y, Masters AR, Quinney SK, Qi X, Woods H, Boulton ME, Meyer JS, Vilseck JZ, Georgiadis MM, Kelley MR, Corson TW. Muniyandi A, et al. Among authors: georgiadis mm. Angiogenesis. 2025 Jan 5;28(1):11. doi: 10.1007/s10456-024-09966-0. Angiogenesis. 2025. PMID: 39756006 Free PMC article.
The absence of Peroxiredoxin-1 in human pancreatic ductal adenocarcinoma (PDAC) markedly reduces cell survival and tumor growth when coupled with the inhibition of Ref-1 redox signaling.
Kiran S, Wireman RS, Peil J, Mitchell DK, Potchanant ES, Rai R, Vilseck JZ, Cao S, Haiaty S, Georgiadis MM, Fishel ML, Kelley MR. Kiran S, et al. Among authors: georgiadis mm. Redox Biol. 2025 Oct;86:103848. doi: 10.1016/j.redox.2025.103848. Epub 2025 Sep 2. Redox Biol. 2025. PMID: 40902319 Free PMC article.
Activation of Gcn2 by small molecules designed to be inhibitors.
Carlson KR, Georgiadis MM, Tameire F, Staschke KA, Wek RC. Carlson KR, et al. Among authors: georgiadis mm. J Biol Chem. 2023 Apr;299(4):104595. doi: 10.1016/j.jbc.2023.104595. Epub 2023 Mar 8. J Biol Chem. 2023. PMID: 36898579 Free PMC article.
Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
Trilles R, Beglov D, Chen Q, He H, Wireman R, Reed A, Chennamadhavuni S, Panek JS, Brown LE, Vajda S, Porco JA Jr, Kelley MR, Georgiadis MM. Trilles R, et al. Among authors: georgiadis mm. J Med Chem. 2019 Feb 28;62(4):1971-1988. doi: 10.1021/acs.jmedchem.8b01529. Epub 2019 Feb 6. J Med Chem. 2019. PMID: 30653918 Free PMC article.
"Skinny" and "Fat" DNA: Two New Double Helices.
Hoshika S, Singh I, Switzer C, Molt RW Jr, Leal NA, Kim MJ, Kim MS, Kim HJ, Georgiadis MM, Benner SA. Hoshika S, et al. Among authors: georgiadis mm. J Am Chem Soc. 2018 Sep 19;140(37):11655-11660. doi: 10.1021/jacs.8b05042. Epub 2018 Sep 10. J Am Chem Soc. 2018. PMID: 30148365
68 results