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1847 4
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1855 2
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1864 5
1865 1
1866 12
1867 2
1868 9
1869 5
1870 5
1871 3
1872 15
1873 7
1874 1
1875 1
1876 2
1877 5
1878 2
1880 2
1881 6
1882 3
1883 10
1887 3
1888 3
1889 4
1890 7
1891 2
1893 1
1894 3
1895 4
1896 2
1897 3
1898 2
1899 5
1900 4
1901 3
1902 2
1904 4
1905 2
1906 1
1907 2
1908 2
1909 5
1910 6
1911 7
1912 6
1913 7
1914 7
1915 4
1916 8
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1918 13
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1920 6
1921 10
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1927 32
1928 18
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1930 23
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1932 14
1933 27
1934 35
1935 28
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1937 34
1938 25
1939 23
1940 26
1941 24
1942 24
1943 25
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1945 199
1946 553
1947 751
1948 801
1949 683
1950 1002
1951 1204
1952 1226
1953 1450
1954 1588
1955 1511
1956 1427
1957 1642
1958 1546
1959 1585
1960 1808
1961 1933
1962 2018
1963 2704
1964 3626
1965 3157
1966 3513
1967 4791
1968 5743
1969 6202
1970 6553
1971 7646
1972 8077
1973 8253
1974 8276
1975 7877
1976 6994
1977 6600
1978 6598
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1980 7045
1981 6813
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1985 8924
1986 9204
1987 9195
1988 9701
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1990 11273
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The following term was not found in PubMed: minkamidopropylamine
Page 1
Detection and quantification of nitric oxide-derived oxidants in biological systems.
Möller MN, Rios N, Trujillo M, Radi R, Denicola A, Alvarez B. Möller MN, et al. J Biol Chem. 2019 Oct 4;294(40):14776-14802. doi: 10.1074/jbc.REV119.006136. Epub 2019 Aug 12. J Biol Chem. 2019. PMID: 31409645 Free PMC article. Review.
The free radical nitric oxide (NO()) exerts biological effects through the direct and reversible interaction with specific targets (e.g. soluble guanylate cyclase) or through the generation of secondary species, many of which can oxidize, nitrosate or nitrate biomol …
The free radical nitric oxide (NO()) exerts biological effects through the direct and reversible interaction with specific targets (e …
Neuroprotective properties of nitric oxide.
Chiueh CC. Chiueh CC. Ann N Y Acad Sci. 1999;890:301-11. doi: 10.1111/j.1749-6632.1999.tb08007.x. Ann N Y Acad Sci. 1999. PMID: 10668435 Review.
Moreover, CO2 and .NO neutralize prooxidative effects of ONOO-. CO2 prevents protein oxidation but not 3-nitrotyrosine formation caused by ONOO-. Finally, neuroprotective effects of GSNO and .NO have been demonstrated in brain preparations in vivo. ...-->GSNO-->.NO + …
Moreover, CO2 and .NO neutralize prooxidative effects of ONOO-. CO2 prevents protein oxidation but not 3-nitrotyrosine formation caus …
Peroxynitrite, a stealthy biological oxidant.
Radi R. Radi R. J Biol Chem. 2013 Sep 13;288(37):26464-72. doi: 10.1074/jbc.R113.472936. Epub 2013 Jul 16. J Biol Chem. 2013. PMID: 23861390 Free PMC article. Review.
Peroxynitrite is the product of the diffusion-controlled reaction of nitric oxide and superoxide radicals. Peroxynitrite, a reactive short-lived peroxide with a pKa of 6.8, is a good oxidant and nucleophile. It also yields secondary free radical intermediates such a …
Peroxynitrite is the product of the diffusion-controlled reaction of nitric oxide and superoxide radicals. Peroxynitrite, a reactive …
Oxidant-mediated modification and cross-linking of beta-2-microglobulin.
Jiang S, Fuentes-Lemus E, Davies MJ. Jiang S, et al. Free Radic Biol Med. 2022 Jul;187:59-71. doi: 10.1016/j.freeradbiomed.2022.05.012. Epub 2022 May 21. Free Radic Biol Med. 2022. PMID: 35609861 Free article.
In the current study we examine the chemical and structural changes induced of B2M generated by both inflammatory oxidants (HOCl and ONOOH), and photo-oxidation ((1)O(2)) which is linked with immunosuppression. ...LC-MS analysis provided evidence for nitrated (from …
In the current study we examine the chemical and structural changes induced of B2M generated by both inflammatory oxidants (HOCl and …
Superoxide, nitric oxide and peroxynitrite production by macrophages under different physiological oxygen tensions.
Casella AC, Prolo C, Pereyra J, Ríos N, Piacenza L, Radi R, Álvarez MN. Casella AC, et al. Free Radic Biol Med. 2024 Feb 20;212:330-335. doi: 10.1016/j.freeradbiomed.2023.12.024. Epub 2023 Dec 21. Free Radic Biol Med. 2024. PMID: 38141888
Macrophages count on two O(2)-consuming enzymes to form reactive radical species: NAPDH oxidase 2 (Nox2) and nitric oxide synthase 2 (inducible isoform, iNOS) that produce superoxide radical (O(2)()(-)) and nitric oxide (()NO), respectively. ...Consequently, peroxyn …
Macrophages count on two O(2)-consuming enzymes to form reactive radical species: NAPDH oxidase 2 (Nox2) and nitric oxide synthase 2 …
Oxidants and antioxidants in atherosclerosis.
Mashima R, Witting PK, Stocker R. Mashima R, et al. Curr Opin Lipidol. 2001 Aug;12(4):411-8. doi: 10.1097/00041433-200108000-00007. Curr Opin Lipidol. 2001. PMID: 11507326 Review.
The oxidative theory suggests that LDL oxidation contributes to atherogenesis, implying that attenuation of this process by antioxidants should decrease atherosclerosis. However, a causative link between LDL oxidation and atherogenesis is not firmly establish …
The oxidative theory suggests that LDL oxidation contributes to atherogenesis, implying that attenuation of this process by an …
Detection, identification, and quantification of oxidative protein modifications.
Hawkins CL, Davies MJ. Hawkins CL, et al. J Biol Chem. 2019 Dec 20;294(51):19683-19708. doi: 10.1074/jbc.REV119.006217. Epub 2019 Oct 31. J Biol Chem. 2019. PMID: 31672919 Free PMC article. Review.
Exposure of biological molecules to oxidants is inevitable and therefore commonplace. Oxidative stress in cells arises from both external agents and endogenous processes that generate reactive species, either purposely (e.g. during pathogen killing or enzymatic reac …
Exposure of biological molecules to oxidants is inevitable and therefore commonplace. Oxidative stress in cells arises from bo …
Nitric oxide and its role in lipid peroxidation.
Violi F, Marino R, Milite MT, Loffredo L. Violi F, et al. Diabetes Metab Res Rev. 1999 Jul-Aug;15(4):283-8. doi: 10.1002/(sici)1520-7560(199907/08)15:4<283::aid-dmrr42>3.0.co;2-u. Diabetes Metab Res Rev. 1999. PMID: 10495477 Review.
Nitric oxide (NO) is a free radical with an unpaired electron in the highest orbital. This is why it behaves as a potential antioxidant agent by virtue of its ability to reduce other molecules. ...However, NO is rapidly inactivated by the superoxide anion (O(*2) to form pe …
Nitric oxide (NO) is a free radical with an unpaired electron in the highest orbital. This is why it behaves as a potential antioxida …
Interaction between reactive oxygen metabolites and nitric oxide in oxidant tolerance.
Cepinskas G, Rui T, Kvietys PR. Cepinskas G, et al. Free Radic Biol Med. 2002 Aug 15;33(4):433-40. doi: 10.1016/s0891-5849(02)00962-0. Free Radic Biol Med. 2002. PMID: 12160925 Review.
Herein, we will focus on a beneficial effect of ROM generation that leads to the development of an adaptive response that protects tissue from a subsequent oxidative stress (oxidant tolerance). We will focus on reductionist approaches (studies in isolated cells) use …
Herein, we will focus on a beneficial effect of ROM generation that leads to the development of an adaptive response that protects tissue fr …
Heme degradation and vascular injury.
Belcher JD, Beckman JD, Balla G, Balla J, Vercellotti G. Belcher JD, et al. Antioxid Redox Signal. 2010 Feb;12(2):233-48. doi: 10.1089/ars.2009.2822. Antioxid Redox Signal. 2010. PMID: 19697995 Free PMC article. Review.
Hydrogen peroxide can split the heme ring and release "free" redox-active iron, which catalytically amplifies the production of reactive oxygen species. These oxidants can oxidize lipids, proteins, and DNA; activate cell-signaling pathways and oxidant-sensiti …
Hydrogen peroxide can split the heme ring and release "free" redox-active iron, which catalytically amplifies the production of reactive oxy …
1,873,313 results
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