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825 results

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Minute virus of mice NS1 redirects casein kinase 2 specificity to suppress the ATR DNA damage response pathway during infection.
Etingov I, Pintel DJ. Etingov I, et al. J Virol. 2024 Dec 17;98(12):e0055924. doi: 10.1128/jvi.00559-24. Epub 2024 Nov 20. J Virol. 2024. PMID: 39565137 Free PMC article.
During infection the autonomous parvovirus minute virus of mice (MVM) generates extensive DNA damage which facilitates virus replication and induces a cellular DNA damage response (DDR) driven by the ataxia telangiectasia mutated (ATM) kinase. . …
During infection the autonomous parvovirus minute virus of mice (MVM) generates extensive DNA damage which facil …
Genomes of the autonomous parvovirus minute virus of mice induce replication stress through RPA exhaustion.
Haubold MK, Aquino JNP, Rubin SR, Jones IK, Larsen CIS, Pham E, Majumder K. Haubold MK, et al. PLoS Pathog. 2023 May 30;19(5):e1011203. doi: 10.1371/journal.ppat.1011203. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37253065 Free PMC article.
The oncolytic autonomous parvovirus Minute Virus of Mice (MVM) establishes infection in the nuclear environment by usurping host DNA damage signaling proteins in the vicinity of cellular DNA break sites. ...Using single molecule DNA Fiber Analysis, we …
The oncolytic autonomous parvovirus Minute Virus of Mice (MVM) establishes infection in the nuclear environment …
Detection of Minute virus of mice strains in different cell lines: Implications for adventitious agent testing.
Farcet MR, Modrof J, Antoine G, Klausen C, Kerschbaum A, Kopp M, Dehghani H, Kreil TR. Farcet MR, et al. Biotechnol Bioeng. 2024 Jan;121(1):131-138. doi: 10.1002/bit.28573. Epub 2023 Oct 19. Biotechnol Bioeng. 2024. PMID: 37855050
Minute virus of mice (MMV) has contaminated biotechnological processes in the past and specific MMV testing is therefore recommended, if the production cell line is known to be permissive for this virus. Testing is widely done using cell-culture …
Minute virus of mice (MMV) has contaminated biotechnological processes in the past and specific MMV testing is t …
Mechanistic modeling of minute virus of mice surrogate removal by anion exchange chromatography in micro scale.
Döring L, Winderl J, Kron M, Hubbuch J. Döring L, et al. J Chromatogr A. 2024 Oct 11;1734:465261. doi: 10.1016/j.chroma.2024.465261. Epub 2024 Aug 17. J Chromatogr A. 2024. PMID: 39216284 Free article.
However, the impact of various process parameters on virus removal by AEX is still not fully understood. Mechanistic modeling could be a promising way to approach this gap, as these models require comparatively few experiments for calibration. This makes them a valuable to …
However, the impact of various process parameters on virus removal by AEX is still not fully understood. Mechanistic modeling could b …
The Autonomous Parvovirus Minute Virus of Mice Localizes to Cellular Sites of DNA Damage Using ATR Signaling.
Larsen CIS, Majumder K. Larsen CIS, et al. Viruses. 2023 May 25;15(6):1243. doi: 10.3390/v15061243. Viruses. 2023. PMID: 37376543 Free PMC article.
Minute Virus of Mice (MVM) is an autonomous parvovirus of the Parvoviridae family that replicates in mouse cells and transformed human cells. ...These observations suggest that the initial localization of MVM to cellular DDR sites depends on ATR signal …
Minute Virus of Mice (MVM) is an autonomous parvovirus of the Parvoviridae family that replicates in mouse cells …
Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection.
Fuller MS, Majumder K, Pintel DJ. Fuller MS, et al. J Virol. 2017 Jun 26;91(14):e00428-17. doi: 10.1128/JVI.00428-17. Print 2017 Jul 15. J Virol. 2017. PMID: 28446681 Free PMC article.
Replication of minute virus of mice (MVM) induces a sustained cellular DNA damage response (DDR) which the virus then exploits to prepare the nuclear environment for effective parvovirus takeover. ...Targeting of a constitutively active FoxM1 co …
Replication of minute virus of mice (MVM) induces a sustained cellular DNA damage response (DDR) which the vi …
Removal of minute virus of mice-mock virus particles by nanofiltration of culture growth medium supplemented with 10% human platelet lysate.
Barro L, Delila L, Nebie O, Wu YW, Knutson F, Watanabe N, Takahara M, Burnouf T. Barro L, et al. Cytotherapy. 2021 Oct;23(10):902-907. doi: 10.1016/j.jcyt.2021.05.006. Epub 2021 Jul 5. Cytotherapy. 2021. PMID: 34238658
METHODS: Herein, we report viral clearance achieved by this nanofiltration process used for assessing a new experimental model using non-infectious minute virus of mice-mock virus particle (MVM-MVP) and its quantification by an immunoqPCR. ...
METHODS: Herein, we report viral clearance achieved by this nanofiltration process used for assessing a new experimental model using non-inf …
Efficacy of minute virus of mice (MVM) inactivation utilizing high temperature short time (HTST) pasteurization and suitability assessment of pasteurized, concentrated glucose feeds in Chinese hamster ovary (CHO) cell expression systems.
Gemmell DK, Mack A, Wegmann S, Han D, Tuccelli R, Johnson M, Miller C. Gemmell DK, et al. Eng Life Sci. 2021 Jun 11;21(7):502-513. doi: 10.1002/elsc.202100044. eCollection 2021 Jul. Eng Life Sci. 2021. PMID: 34257631 Free PMC article.
We demonstrated approximately six log inactivation of Minute Virus of Mice (MVM) in concentrated glucose feeds without impacting the subsequent performance of the glucose in a Chinese Hamster Ovary (CHO) expression system....
We demonstrated approximately six log inactivation of Minute Virus of Mice (MVM) in concentrated glucose feeds w …
Protein Myristoylation Plays a Role in the Nuclear Entry of the Parvovirus Minute Virus of Mice.
Yang S, Zhou L, Panté N. Yang S, et al. J Virol. 2022 Sep 14;96(17):e0111822. doi: 10.1128/jvi.01118-22. Epub 2022 Aug 11. J Virol. 2022. PMID: 35950857 Free PMC article.
As these viruses replicate in the host cell nucleus, they must gain access to the nucleus during infection. The PV minute virus of mice (MVM) and several other PVs transiently disrupt the nuclear envelope (NE) and enter the nucleus through the resultin …
As these viruses replicate in the host cell nucleus, they must gain access to the nucleus during infection. The PV minute virus …
Heat-induced transitions of an empty minute virus of mice capsid in explicit water: all-atom MD simulation.
Pathak AK, Bandyopadhyay T. Pathak AK, et al. J Biomol Struct Dyn. 2022;40(22):11900-11913. doi: 10.1080/07391102.2021.1969283. Epub 2021 Aug 30. J Biomol Struct Dyn. 2022. PMID: 34459706
The capsid-like structure of the virus-based protein nanoparticles (NPs) can serve as bionanomaterials, with applications in biomedicines and nanotechnology. ...Here, we have calculated heat induced changes in the properties of an empty minute virus of …
The capsid-like structure of the virus-based protein nanoparticles (NPs) can serve as bionanomaterials, with applications in biomedic …
825 results