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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1913 1
1914 1
1915 1
1916 1
1918 2
1920 1
1921 3
1922 1
1923 3
1924 3
1925 2
1926 1
1927 2
1929 1
1930 1
1931 3
1932 1
1933 3
1935 2
1937 1
1939 1
1943 1
1944 1
1945 4
1946 6
1947 9
1948 12
1949 15
1950 23
1951 36
1952 49
1953 107
1954 90
1955 104
1956 167
1957 173
1958 161
1959 219
1960 275
1961 288
1962 346
1963 597
1964 945
1965 965
1966 1207
1967 1618
1968 1914
1969 2237
1970 2484
1971 2851
1972 3199
1973 3354
1974 3216
1975 3304
1976 2941
1977 2822
1978 2671
1979 2873
1980 2866
1981 2656
1982 2906
1983 2994
1984 3158
1985 3172
1986 3108
1987 3030
1988 3107
1989 3482
1990 3575
1991 3515
1992 3551
1993 3691
1994 3710
1995 3958
1996 4138
1997 4182
1998 4738
1999 4898
2000 5720
2001 6518
2002 6934
2003 7392
2004 8470
2005 8882
2006 9587
2007 10421
2008 10833
2009 11527
2010 12692
2011 13413
2012 14769
2013 15969
2014 17511
2015 18312
2016 19869
2017 19213
2018 19829
2019 21590
2020 23805
2021 25574
2022 24726
2023 24168
2024 14799
2025 10

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441,356 results

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Page 1
Mitochondrial abnormalities in Parkinson's disease and Alzheimer's disease: can mitochondria be targeted therapeutically?
Macdonald R, Barnes K, Hastings C, Mortiboys H. Macdonald R, et al. Biochem Soc Trans. 2018 Aug 20;46(4):891-909. doi: 10.1042/BST20170501. Epub 2018 Jul 19. Biochem Soc Trans. 2018. PMID: 30026371 Free article. Review.
Mitochondrial abnormalities have been identified as a central mechanism in multiple neurodegenerative diseases and, therefore, the mitochondria have been explored as a therapeutic target. ...In addition, we discuss the main strategies which have been explored in the
Mitochondrial abnormalities have been identified as a central mechanism in multiple neurodegenerative diseases and, therefore, the
Mitochondrial dysfunction in diabetic kidney disease.
Forbes JM, Thorburn DR. Forbes JM, et al. Nat Rev Nephrol. 2018 May;14(5):291-312. doi: 10.1038/nrneph.2018.9. Epub 2018 Feb 19. Nat Rev Nephrol. 2018. PMID: 29456246 Review.
Despite this burden, the factors that precipitate the development and progression of diabetic kidney disease (DKD) remain to be fully elucidated. Mitochondrial dysfunction is associated with kidney disease in nondiabetic contexts, and increasing evidence suggests that dysf …
Despite this burden, the factors that precipitate the development and progression of diabetic kidney disease (DKD) remain to be fully elucid …
Pathways to balance mitochondrial translation and protein import.
Priesnitz C, Becker T. Priesnitz C, et al. Genes Dev. 2018 Oct 1;32(19-20):1285-1296. doi: 10.1101/gad.316547.118. Genes Dev. 2018. PMID: 30275044 Free PMC article. Review.
Mitochondria contain their own genome that encodes for a small number of proteins, while the vast majority of mitochondrial proteins is produced on cytosolic ribosomes. The formation of respiratory chain complexes depends on the coordinated biogenesis of mitochon
Mitochondria contain their own genome that encodes for a small number of proteins, while the vast majority of mitochondrial pr
Mitochondrial Glucocorticoid Receptors and Their Actions.
Kokkinopoulou I, Moutsatsou P. Kokkinopoulou I, et al. Int J Mol Sci. 2021 Jun 3;22(11):6054. doi: 10.3390/ijms22116054. Int J Mol Sci. 2021. PMID: 34205227 Free PMC article. Review.
Glucocorticoids (GCs) regulate the mitochondrially encoded oxidative phosphorylation gene expression and mitochondrial energy metabolism. ...Numerous studies have revealed changes in mitochondrial gene expression alongside with GR import/export in mitochon
Glucocorticoids (GCs) regulate the mitochondrially encoded oxidative phosphorylation gene expression and mitochondrial energy …
Requirements for successful mitochondrial transplantation.
Kubat GB, Ulger O, Akin S. Kubat GB, et al. J Biochem Mol Toxicol. 2021 Nov;35(11):e22898. doi: 10.1002/jbt.22898. Epub 2021 Aug 25. J Biochem Mol Toxicol. 2021. PMID: 34435410 Review.
Maintenance of mitochondrial oxidative phosphorylation capacity and other mitochondrial functions are essential for the prevention of mitochondrial dysfunction-related diseases such as neurodegenerative, cardiovascular, and liver diseases. ...The animal and h …
Maintenance of mitochondrial oxidative phosphorylation capacity and other mitochondrial functions are essential for the preven …
Mitochondrial Dysfunction at the Center of Cancer Therapy.
Chiu HY, Tay EXY, Ong DST, Taneja R. Chiu HY, et al. Antioxid Redox Signal. 2020 Feb 10;32(5):309-330. doi: 10.1089/ars.2019.7898. Epub 2019 Nov 4. Antioxid Redox Signal. 2020. PMID: 31578870 Review.
Unsurprisingly, mitochondrial dysfunctions underlie many pathologies including cancer. ...However, the efficacy of these treatments varies across different cancer cells. It has been suggested that mitochondria may be at the center of these diverse responses. In the …
Unsurprisingly, mitochondrial dysfunctions underlie many pathologies including cancer. ...However, the efficacy of these treatments v …
Oxidative Stress and Hypoxia Modify Mitochondrial Homeostasis During Glaucoma.
Jassim AH, Fan Y, Pappenhagen N, Nsiah NY, Inman DM. Jassim AH, et al. Antioxid Redox Signal. 2021 Dec;35(16):1341-1357. doi: 10.1089/ars.2020.8180. Epub 2021 Apr 29. Antioxid Redox Signal. 2021. PMID: 33736457 Free PMC article.
Aims: Cellular response to hypoxia can include transition from respiration to glycolysis via upregulation of glycolytic enzymes and transporters, as well as mitophagy induction to eliminate surplus mitochondria. Our purpose was to evaluate the impact of hypoxia-inducible f …
Aims: Cellular response to hypoxia can include transition from respiration to glycolysis via upregulation of glycolytic enzymes and transpor …
Mitochondrial ageing.
Szibor M, Holtz J. Szibor M, et al. Basic Res Cardiol. 2003 Jul;98(4):210-8. doi: 10.1007/s00395-003-0421-z. Basic Res Cardiol. 2003. PMID: 12835950 Review.
Their replacement during normal turnover requires an intergenomic coordination between the mitochondrial genome (mtDNA, encoding for 13 protein subunits of the respiratory chain, two mitochondrial rRNAs and the 22 mitochondrial tRNAs) and the nuclear genome ( …
Their replacement during normal turnover requires an intergenomic coordination between the mitochondrial genome (mtDNA, encoding for …
Mitochondrial anti-viral immunity.
Zemirli N, Arnoult D. Zemirli N, et al. Int J Biochem Cell Biol. 2012 Sep;44(9):1473-6. doi: 10.1016/j.biocel.2012.05.018. Epub 2012 Jun 1. Int J Biochem Cell Biol. 2012. PMID: 22664327 Review.
Hence, in addition to their known roles in the metabolic processes and the control of programmed cell death, mitochondria are now emerging as a fundamental hub for innate anti-viral immunity. This review summarizes the findings related to the MAVS adapter and mitochondr
Hence, in addition to their known roles in the metabolic processes and the control of programmed cell death, mitochondria are now eme …
Interrogating Mitochondrial Biology and Disease Using CRISPR/Cas9 Gene Editing.
Tang JX, Pyle A, Taylor RW, Oláhová M. Tang JX, et al. Genes (Basel). 2021 Oct 12;12(10):1604. doi: 10.3390/genes12101604. Genes (Basel). 2021. PMID: 34680998 Free PMC article. Review.
Mitochondrial disease originates from genetic changes that impact human bodily functions by disrupting the mitochondrial oxidative phosphorylation system. MitoCarta is a curated and published inventory that sheds light on the mitochondrial proteome, but the f
Mitochondrial disease originates from genetic changes that impact human bodily functions by disrupting the mitochondrial oxida
441,356 results
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