Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1967 3
1968 7
1969 7
1970 13
1971 9
1972 20
1973 19
1974 18
1975 24
1976 28
1977 20
1978 9
1979 22
1980 26
1981 20
1982 16
1983 13
1984 15
1985 11
1986 14
1987 18
1988 28
1989 28
1990 27
1991 24
1992 33
1993 42
1994 32
1995 61
1996 44
1997 46
1998 67
1999 81
2000 97
2001 90
2002 120
2003 135
2004 163
2005 192
2006 218
2007 303
2008 311
2009 391
2010 445
2011 527
2012 648
2013 671
2014 720
2015 897
2016 990
2017 1031
2018 1055
2019 1070
2020 1253
2021 1285
2022 1219
2023 1145
2024 1236
2025 1611
2026 404

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

16,879 results

Results by year

Filters applied: . Clear all
Page 1
Mitochondrial biogenesis: An update.
Popov LD. Popov LD. J Cell Mol Med. 2020 May;24(9):4892-4899. doi: 10.1111/jcmm.15194. Epub 2020 Apr 12. J Cell Mol Med. 2020. PMID: 32279443 Free PMC article. Review.
Recently, considerable progress has been made in deciphering mitochondrial biogenesis-related proteins and genes that function in health and in pathology-related circumstances. However, an outlook on the intracellular mechanisms shared by the main players that drive …
Recently, considerable progress has been made in deciphering mitochondrial biogenesis-related proteins and genes that function …
Regulation of mitochondrial biogenesis.
Jornayvaz FR, Shulman GI. Jornayvaz FR, et al. Essays Biochem. 2010;47:69-84. doi: 10.1042/bse0470069. Essays Biochem. 2010. PMID: 20533901 Free PMC article. Review.
The latter drives transcription and replication of mitochondrial DNA. PGC-1alpha itself is regulated by several different key factors involved in mitochondrial biogenesis, which will be reviewed in this chapter. ...AMPK acts as an energy sensor of the cell an …
The latter drives transcription and replication of mitochondrial DNA. PGC-1alpha itself is regulated by several different key factors …
Crosstalk between mitochondrial biogenesis and mitophagy to maintain mitochondrial homeostasis.
Liu L, Li Y, Chen G, Chen Q. Liu L, et al. J Biomed Sci. 2023 Oct 12;30(1):86. doi: 10.1186/s12929-023-00975-7. J Biomed Sci. 2023. PMID: 37821940 Free PMC article. Review.
Mitochondrial mass and quality are tightly regulated by two essential and opposing mechanisms, mitochondrial biogenesis (mitobiogenesis) and mitophagy, in response to cellular energy needs and other cellular and environmental cues. ...
Mitochondrial mass and quality are tightly regulated by two essential and opposing mechanisms, mitochondrial biogenesis …
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y. Zhao T, et al. EMBO J. 2023 Aug 15;42(16):e113258. doi: 10.15252/embj.2022113258. Epub 2023 Jul 6. EMBO J. 2023. PMID: 37409632 Free PMC article.
Mitochondrial biogenesis is the process of generating new mitochondria to maintain cellular homeostasis. Here, we report that viruses exploit mitochondrial biogenesis to antagonize innate antiviral immunity. We found that nuclear respiratory factor-1 ( …
Mitochondrial biogenesis is the process of generating new mitochondria to maintain cellular homeostasis. Here, we report that …
Serine synthesis controls mitochondrial biogenesis in macrophages.
Wang C, Zhao M, Bin P, Ye Y, Chen Q, Tang Z, Ren W. Wang C, et al. Sci Adv. 2024 May 17;10(20):eadn2867. doi: 10.1126/sciadv.adn2867. Epub 2024 May 17. Sci Adv. 2024. PMID: 38758794 Free PMC article.
Mitochondrial dysfunction is the pivotal driving factor of multiple inflammatory diseases, and targeting mitochondrial biogenesis represents an efficacious approach to ameliorate such dysfunction in inflammatory diseases. ...Collectively, this study reveals t …
Mitochondrial dysfunction is the pivotal driving factor of multiple inflammatory diseases, and targeting mitochondrial biog …
Harnessing tissue-derived mitochondria-rich extracellular vesicles (Ti-mitoEVs) to boost mitochondrial biogenesis for regenerative medicine.
Lou P, Zhou X, Zhang Y, Xie Y, Wang Y, Wang C, Liu S, Wan M, Lu Y, Liu J. Lou P, et al. Sci Adv. 2025 Jul 18;11(29):eadt1318. doi: 10.1126/sciadv.adt1318. Epub 2025 Jul 16. Sci Adv. 2025. PMID: 40668934 Free PMC article.
In vitro, Ti-mitoEV treatment increased mitochondrial biogenesis and reduced mitochondrial damage in recipient cells, and these effects occurred at least partly via mitochondrial genome transfer. ...This study highlights the promising role of Ti-mitoEV …
In vitro, Ti-mitoEV treatment increased mitochondrial biogenesis and reduced mitochondrial damage in recipient cells, a …
The Role of PGC-1alpha and Mitochondrial Biogenesis in Kidney Diseases.
Fontecha-Barriuso M, Martin-Sanchez D, Martinez-Moreno JM, Monsalve M, Ramos AM, Sanchez-Niño MD, Ruiz-Ortega M, Ortiz A, Sanz AB. Fontecha-Barriuso M, et al. Biomolecules. 2020 Feb 24;10(2):347. doi: 10.3390/biom10020347. Biomolecules. 2020. PMID: 32102312 Free PMC article. Review.
CKD predisposes to acute kidney injury (AKI) and AKI favors CKD progression. Mitochondrial derangements are common features of both AKI and CKD and mitochondria-targeting therapies are under study as nephroprotective agents. PGC-1alpha is a master regulator of mitochond …
CKD predisposes to acute kidney injury (AKI) and AKI favors CKD progression. Mitochondrial derangements are common features of both A …
Mitochondrial Biogenesis in Neurons: How and Where.
Cardanho-Ramos C, Morais VA. Cardanho-Ramos C, et al. Int J Mol Sci. 2021 Dec 2;22(23):13059. doi: 10.3390/ijms222313059. Int J Mol Sci. 2021. PMID: 34884861 Free PMC article. Review.
However, in long cells, like motor neurons, this constant travel back and forth is not an energetically favourable process, thus mitochondrial biogenesis must also occur at the periphery. Ca(2+) and ATP levels are the main triggers for mitochondrial biogen …
However, in long cells, like motor neurons, this constant travel back and forth is not an energetically favourable process, thus mitochon …
Mitochondrial Biogenesis in Skeletal Muscle.
Hood DA, Memme JM, Oliveira AN, Moradi N, Champsi S. Hood DA, et al. Adv Exp Med Biol. 2025;1478:19-50. doi: 10.1007/978-3-031-88361-3_2. Adv Exp Med Biol. 2025. PMID: 40879934 Review.
Mitochondrial biogenesis refers to the synthesis of nuclear- and mitochondrially encoded proteins, along with phospholipids, that aid in the expansion of the mitochondrial network. ...This chapter marks the introduction to skeletal muscle mitochondrial …
Mitochondrial biogenesis refers to the synthesis of nuclear- and mitochondrially encoded proteins, along with phospholipids, t …
Progress in Nonalcoholic Fatty Liver Disease: SIRT Family Regulates Mitochondrial Biogenesis.
Zeng C, Chen M. Zeng C, et al. Biomolecules. 2022 Aug 5;12(8):1079. doi: 10.3390/biom12081079. Biomolecules. 2022. PMID: 36008973 Free PMC article. Review.
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin resistance, mitochondrial dysfunction, inflammation, and oxidative stress. As a group of NAD+-dependent III deacetylases, the sirtuin (SIRT1-7) family plays a very important role in reg …
Nonalcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis, insulin resistance, mitochondrial dysfunction, inflam …
16,879 results
You have reached the last available page of results. Please see the User Guide for more information.