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Year Number of Results
1913 1
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1920 1
1921 3
1922 1
1923 3
1924 2
1925 1
1926 1
1927 2
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1931 2
1932 1
1933 2
1935 2
1937 1
1939 1
1943 1
1944 1
1945 4
1946 6
1947 8
1948 12
1949 15
1950 22
1951 34
1952 48
1953 104
1954 89
1955 99
1956 161
1957 161
1958 154
1959 212
1960 259
1961 275
1962 330
1963 583
1964 940
1965 947
1966 1189
1967 1599
1968 1883
1969 2202
1970 2403
1971 2764
1972 3115
1973 3242
1974 3067
1975 3089
1976 2680
1977 2546
1978 2383
1979 2517
1980 2492
1981 2243
1982 2450
1983 2441
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1985 2578
1986 2484
1987 2358
1988 2428
1989 2670
1990 2715
1991 2649
1992 2566
1993 2453
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1995 2578
1996 2637
1997 2537
1998 2915
1999 2992
2000 3528
2001 3969
2002 4188
2003 4531
2004 5079
2005 5179
2006 5305
2007 5829
2008 6071
2009 6377
2010 6906
2011 7376
2012 8110
2013 8710
2014 9201
2015 9605
2016 10058
2017 10237
2018 10607
2019 11349
2020 12465
2021 12740
2022 11168
2023 10894
2024 12790
2025 14589
2026 8593

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290,626 results

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Page 1
Of mitochondrion and COVID-19.
Alfarouk KO, Alhoufie STS, Hifny A, Schwartz L, Alqahtani AS, Ahmed SBM, Alqahtani AM, Alqahtani SS, Muddathir AK, Ali H, Bashir AHH, Ibrahim ME, Greco MR, Cardone RA, Harguindey S, Reshkin SJ. Alfarouk KO, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1258-1267. doi: 10.1080/14756366.2021.1937144. J Enzyme Inhib Med Chem. 2021. PMID: 34107824 Free PMC article. Review.
Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunction. Therefore, targeting mitochondrion will represent a more rational treatment of COVID-19. The current work outlines how COVID-19's …
Most of the signs and symptoms, e.g. cytokine storm, electrolytes imbalances, thromboembolism, etc., are related to mitochondrial dysfunctio …
Mitochondrion-Targeted Type I Photodynamic Therapy for Agonist Independent cGAS-STING Activation.
Xu Y, An D, Zhang T, Wu X, Wang S, Shao J, Qu LL, Guo Y, Dong X. Xu Y, et al. Adv Mater. 2025 Apr;37(14):e2418894. doi: 10.1002/adma.202418894. Epub 2025 Feb 23. Adv Mater. 2025. PMID: 39988853
The HABH nanoagonist can actively target tumor tissues and release the mitochondrion-targeted BDP. Under light illumination, BDP achieves type I photodynamic therapy (PDT) in mitochondria, generating massive hydroxyl radicals ( OH) and inducing mitochondrial stress …
The HABH nanoagonist can actively target tumor tissues and release the mitochondrion-targeted BDP. Under light illumination, BDP achi …
Mitochondrion-located peptides and their pleiotropic physiological functions.
Zheng X, Xiang M. Zheng X, et al. FEBS J. 2022 Nov;289(22):6919-6935. doi: 10.1111/febs.16532. Epub 2022 Jun 5. FEBS J. 2022. PMID: 35599630 Free article. Review.
Interestingly, a considerable proportion of micropeptides are located in mitochondria, which are designated here as mitochondrion-located peptides (MLPs). These MLPs often contain a transmembrane domain and show a high degree of conservation across species. ...These …
Interestingly, a considerable proportion of micropeptides are located in mitochondria, which are designated here as mitochondrion …
Was the Mitochondrion Necessary to Start Eukaryogenesis?
Hampl V, Čepička I, Eliáš M. Hampl V, et al. Trends Microbiol. 2019 Feb;27(2):96-104. doi: 10.1016/j.tim.2018.10.005. Epub 2018 Nov 19. Trends Microbiol. 2019. PMID: 30466901 Review.
Arguments based on cell energetics favour the view that a mitochondrion capable of oxidative phosphorylation was a prerequisite for the evolution of other features of the eukaryotic cell, including increased volume, genome size and, eventually, phagotrophy. ...We claim tha …
Arguments based on cell energetics favour the view that a mitochondrion capable of oxidative phosphorylation was a prerequisite for t …
Mitochondrion: Main organelle in orchestrating cancer escape from chemotherapy.
Mostafavi S, Eskandari N. Mostafavi S, et al. Cancer Rep (Hoboken). 2024 Feb;7(2):e1942. doi: 10.1002/cnr2.1942. Epub 2023 Dec 27. Cancer Rep (Hoboken). 2024. PMID: 38151790 Free PMC article. Review.
BACKGROUND: Chemoresistance is a challenging barrier to cancer therapy, and in this context, the role of mitochondria is significant. We put emphasis on key biological characteristics of mitochondria, contributing to tumor escape from various therapies, to find the …
BACKGROUND: Chemoresistance is a challenging barrier to cancer therapy, and in this context, the role of mitochondria is significant. …
Microbe-mitochondrion crosstalk and health: An emerging paradigm.
Bajpai P, Darra A, Agrawal A. Bajpai P, et al. Mitochondrion. 2018 Mar;39:20-25. doi: 10.1016/j.mito.2017.08.008. Epub 2017 Aug 24. Mitochondrion. 2018. PMID: 28838618 Review.
Human mitochondria are descendants of microbes and altered mitochondrial function has been implicated in processes ranging from ageing to diabetes. ...Overall, while there is compelling evidence that a microbiota-mitochondria link exists, explicit and holistic mecha …
Human mitochondria are descendants of microbes and altered mitochondrial function has been implicated in processes ranging from agein …
THE MITOCHONDRION.
GREEN DE. GREEN DE. Sci Am. 1964 Jan;210:67-74. Sci Am. 1964. PMID: 14088563 Review. No abstract available.
Malleable mitochondrion of Trypanosoma brucei.
Verner Z, Basu S, Benz C, Dixit S, Dobáková E, Faktorová D, Hashimi H, Horáková E, Huang Z, Paris Z, Peña-Diaz P, Ridlon L, Týč J, Wildridge D, Zíková A, Lukeš J. Verner Z, et al. Int Rev Cell Mol Biol. 2015;315:73-151. doi: 10.1016/bs.ircmb.2014.11.001. Epub 2015 Feb 7. Int Rev Cell Mol Biol. 2015. PMID: 25708462 Review.
The importance of mitochondria for a typical aerobic eukaryotic cell is undeniable, as the list of necessary mitochondrial processes is steadily growing. ...As we describe in this chapter, the single mitochondrion of T. brucei is everything but simple and as such ri …
The importance of mitochondria for a typical aerobic eukaryotic cell is undeniable, as the list of necessary mitochondrial processes …
Mitochondrial dysfunction and mitochondrion-targeted therapeutics in liver diseases.
Xiang L, Shao Y, Chen Y. Xiang L, et al. J Drug Target. 2021 Dec;29(10):1080-1093. doi: 10.1080/1061186X.2021.1909051. Epub 2021 Apr 9. J Drug Target. 2021. PMID: 33788656 Review.
The liver is a vital metabolic and detoxifying organ and suffers diverse endogenous or exogenous damage. Hepatocyte mitochondria experience various structural and functional defects from liver injury, bearing oxidative stress, metabolic dysregulation, and the disturbance o …
The liver is a vital metabolic and detoxifying organ and suffers diverse endogenous or exogenous damage. Hepatocyte mitochondria expe …
Mitochondrion-related organelles in eukaryotic protists.
Shiflett AM, Johnson PJ. Shiflett AM, et al. Annu Rev Microbiol. 2010;64:409-29. doi: 10.1146/annurev.micro.62.081307.162826. Annu Rev Microbiol. 2010. PMID: 20528687 Free PMC article. Review.
The discovery of mitochondrion-type genes in organisms thought to lack mitochondria led to the demonstration that hydrogenosomes share a common ancestry with mitochondria, as well as the discovery of mitosomes in multiple eukaryotic lineages. ...These organel …
The discovery of mitochondrion-type genes in organisms thought to lack mitochondria led to the demonstration that hydrogenosom …
290,626 results
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