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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 3
1998 2
2001 1
2003 3
2004 7
2005 11
2006 13
2007 24
2008 24
2009 27
2010 46
2011 50
2012 64
2013 84
2014 86
2015 88
2016 107
2017 103
2018 105
2019 137
2020 144
2021 146
2022 86
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1,189 results
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Mitofusin-2: A New Mediator of Pathological Cell Proliferation.
Xin Y, Li J, Wu W, Liu X. Xin Y, et al. Front Cell Dev Biol. 2021 Apr 1;9:647631. doi: 10.3389/fcell.2021.647631. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33869201 Free PMC article. Review.
Mitochondria are highly dynamic organelles whose shape, number, and biological functions are modulated by mitochondrial dynamics, including fusion and fission. Mitofusin-2 (Mfn-2) is an essential GTPase-related mitochondrial dynamics protein for maintaining m …
Mitochondria are highly dynamic organelles whose shape, number, and biological functions are modulated by mitochondrial dynamics, including …
Structure, function, and regulation of mitofusin-2 in health and disease.
Chandhok G, Lazarou M, Neumann B. Chandhok G, et al. Biol Rev Camb Philos Soc. 2018 May;93(2):933-949. doi: 10.1111/brv.12378. Epub 2017 Oct 25. Biol Rev Camb Philos Soc. 2018. PMID: 29068134 Free PMC article. Review.
Mitochondria are highly dynamic organelles that constantly migrate, fuse, and divide to regulate their shape, size, number, and bioenergetic function. Mitofusins (Mfn1/2), optic atrophy 1 (OPA1), and dynamin-related protein 1 (Drp1), are key regulators of mitochondr …
Mitochondria are highly dynamic organelles that constantly migrate, fuse, and divide to regulate their shape, size, number, and bioenergetic …
Mitofusin 2 tethers endoplasmic reticulum to mitochondria.
de Brito OM, Scorrano L. de Brito OM, et al. Nature. 2008 Dec 4;456(7222):605-10. doi: 10.1038/nature07534. Nature. 2008. PMID: 19052620
An in vitro assay as well as genetic and biochemical evidences support a model in which mitofusin 2 on the ER bridges the two organelles by engaging in homotypic and heterotypic complexes with mitofusin 1 or 2 on the surface of mitochondria. Thus, m
An in vitro assay as well as genetic and biochemical evidences support a model in which mitofusin 2 on the ER bridges the two …
Relationship between mitofusin 2 and cancer.
Allegra A, Innao V, Allegra AG, Musolino C. Allegra A, et al. Adv Protein Chem Struct Biol. 2019;116:209-236. doi: 10.1016/bs.apcsb.2018.11.009. Epub 2018 Dec 27. Adv Protein Chem Struct Biol. 2019. PMID: 31036292 Review.
Within the cell, the mitochondrial system is incessantly modified via the balance between fusion and fission processes. Among other proteins, mitofusin 2 is a central protagonist in all these mitochondrial events (fusion, trafficking, contacts with other organelles) …
Within the cell, the mitochondrial system is incessantly modified via the balance between fusion and fission processes. Among other proteins …
Mitofusin 2: A link between mitochondrial function and substrate metabolism?
Emery JM, Ortiz RM. Emery JM, et al. Mitochondrion. 2021 Nov;61:125-137. doi: 10.1016/j.mito.2021.09.003. Epub 2021 Sep 15. Mitochondrion. 2021. PMID: 34536562 Free article. Review.
This "mitochatting" allows the cell to receive information about the mitochondria's condition before accommodating energy demands. Mitofusin 2 (Mfn2), an outer mitochondrial membrane fusion protein specializes in mediating mitochondrial homeostasis. ...
This "mitochatting" allows the cell to receive information about the mitochondria's condition before accommodating energy demands. Mitofu
Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity.
Tur J, Pereira-Lopes S, Vico T, Marín EA, Muñoz JP, Hernández-Alvarez M, Cardona PJ, Zorzano A, Lloberas J, Celada A. Tur J, et al. Cell Rep. 2020 Aug 25;32(8):108079. doi: 10.1016/j.celrep.2020.108079. Cell Rep. 2020. PMID: 32846136 Free article.
Mitofusin 2 (Mfn2) plays a major role in mitochondrial fusion and in the maintenance of mitochondria-endoplasmic reticulum contact sites. ...
Mitofusin 2 (Mfn2) plays a major role in mitochondrial fusion and in the maintenance of mitochondria-endoplasmic reticulum con
Mitofusin 2 Dysfunction and Disease in Mice and Men.
Dorn GW 2nd. Dorn GW 2nd. Front Physiol. 2020 Jul 9;11:782. doi: 10.3389/fphys.2020.00782. eCollection 2020. Front Physiol. 2020. PMID: 32733278 Free PMC article. Review.
A causal relationship between Mitofusin (MFN) 2 gene mutations and the hereditary axonal neuropathy Charcot-Marie-Tooth disease type 2A (CMT2A) was described over 15 years ago. ...Finally, in the context of recently described mitofusin activating peptides and …
A causal relationship between Mitofusin (MFN) 2 gene mutations and the hereditary axonal neuropathy Charcot-Marie-Tooth diseas …
Mitofusin 2, a key coordinator between mitochondrial dynamics and innate immunity.
Kim IS, Silwal P, Jo EK. Kim IS, et al. Virulence. 2021 Dec;12(1):2273-2284. doi: 10.1080/21505594.2021.1965829. Virulence. 2021. PMID: 34482801 Free PMC article. Review.
In addition to their role in metabolism and energy production, mitochondria participate in diverse biological functions, including innate immune responses driven by macrophages in response to infections or inflammatory stimuli. Mitofusin-2 (MFN2), a mitochondria-sha …
In addition to their role in metabolism and energy production, mitochondria participate in diverse biological functions, including innate im …
Mitofusin 2: from functions to disease.
Filadi R, Pendin D, Pizzo P. Filadi R, et al. Cell Death Dis. 2018 Feb 28;9(3):330. doi: 10.1038/s41419-017-0023-6. Cell Death Dis. 2018. PMID: 29491355 Free PMC article. Review.
Being mitochondria key bioenergetics organelles, they have to be transported to all the specific high-energy demanding sites within the cell and, when damaged, they have to be efficiently removed. Among other proteins, Mitofusin 2 represents a key player in all thes …
Being mitochondria key bioenergetics organelles, they have to be transported to all the specific high-energy demanding sites within the cell …
1,189 results