Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 3
1998 2
2001 1
2003 3
2004 7
2005 11
2006 13
2007 24
2008 24
2009 27
2010 46
2011 50
2012 64
2013 84
2014 86
2015 87
2016 106
2017 103
2018 104
2019 136
2020 125
2021 2
Text availability
Article attribute
Article type
Publication date

Search Results

971 results
Results by year
Filters applied: . Clear all
Page 1
Mitofusin 2 tethers endoplasmic reticulum to mitochondria.
de Brito OM, Scorrano L. de Brito OM, et al. Nature. 2008 Dec 4;456(7222):605-10. doi: 10.1038/nature07534. Nature. 2008. PMID: 19052620
An in vitro assay as well as genetic and biochemical evidences support a model in which mitofusin 2 on the ER bridges the two organelles by engaging in homotypic and heterotypic complexes with mitofusin 1 or 2 on the surface of mitochondria. Thus, m
An in vitro assay as well as genetic and biochemical evidences support a model in which mitofusin 2 on the ER bridges the two …
Mitofusin 2: from functions to disease.
Filadi R, Pendin D, Pizzo P. Filadi R, et al. Cell Death Dis. 2018 Feb 28;9(3):330. doi: 10.1038/s41419-017-0023-6. Cell Death Dis. 2018. PMID: 29491355 Free PMC article. Review.
Being mitochondria key bioenergetics organelles, they have to be transported to all the specific high-energy demanding sites within the cell and, when damaged, they have to be efficiently removed. Among other proteins, Mitofusin 2 represents a key player in all thes …
Being mitochondria key bioenergetics organelles, they have to be transported to all the specific high-energy demanding sites within the cell …
Structure, function, and regulation of mitofusin-2 in health and disease.
Chandhok G, Lazarou M, Neumann B. Chandhok G, et al. Biol Rev Camb Philos Soc. 2018 May;93(2):933-949. doi: 10.1111/brv.12378. Epub 2017 Oct 25. Biol Rev Camb Philos Soc. 2018. PMID: 29068134 Free PMC article. Review.
Mitochondria are highly dynamic organelles that constantly migrate, fuse, and divide to regulate their shape, size, number, and bioenergetic function. Mitofusins (Mfn1/2), optic atrophy 1 (OPA1), and dynamin-related protein 1 (Drp1), are key regulators of mitochondr …
Mitochondria are highly dynamic organelles that constantly migrate, fuse, and divide to regulate their shape, size, number, and bioenergetic …
Relationship between mitofusin 2 and cancer.
Allegra A, Innao V, Allegra AG, Musolino C. Allegra A, et al. Adv Protein Chem Struct Biol. 2019;116:209-236. doi: 10.1016/bs.apcsb.2018.11.009. Epub 2018 Dec 27. Adv Protein Chem Struct Biol. 2019. PMID: 31036292 Review.
Within the cell, the mitochondrial system is incessantly modified via the balance between fusion and fission processes. Among other proteins, mitofusin 2 is a central protagonist in all these mitochondrial events (fusion, trafficking, contacts with other organelles) …
Within the cell, the mitochondrial system is incessantly modified via the balance between fusion and fission processes. Among other proteins …
Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling.
Filadi R, Greotti E, Turacchio G, Luini A, Pozzan T, Pizzo P. Filadi R, et al. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2174-81. doi: 10.1073/pnas.1504880112. Epub 2015 Apr 13. Proc Natl Acad Sci U S A. 2015. PMID: 25870285 Free PMC article.
Several proteins have been suggested to be involved in keeping ER and mitochondria at a correct distance. Among them, in mammalian cells, mitofusin 2 (Mfn2), located on both the outer mitochondrial membrane and the ER surface, has been proposed to be a physical teth …
Several proteins have been suggested to be involved in keeping ER and mitochondria at a correct distance. Among them, in mammalian cells, …
Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications.
Rovira-Llopis S, Bañuls C, Diaz-Morales N, Hernandez-Mijares A, Rocha M, Victor VM. Rovira-Llopis S, et al. Redox Biol. 2017 Apr;11:637-645. doi: 10.1016/j.redox.2017.01.013. Epub 2017 Jan 16. Redox Biol. 2017. PMID: 28131082 Free PMC article. Review.
Mitochondrial fusion is modulated by different proteins, including mitofusin-1 (MFN1), mitofusin-2 (MFN2) and optic atrophy (OPA-1), while fission is controlled by mitochondrial fission 1 (FIS1), dynamin-related protein 1 (DRP1) and mitochondrial fission fact …
Mitochondrial fusion is modulated by different proteins, including mitofusin-1 (MFN1), mitofusin-2 (MFN2) and optic atr …
Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential.
Luchsinger LL, de Almeida MJ, Corrigan DJ, Mumau M, Snoeck HW. Luchsinger LL, et al. Nature. 2016 Jan 28;529(7587):528-31. doi: 10.1038/nature16500. Epub 2016 Jan 20. Nature. 2016. PMID: 26789249 Free PMC article.
Here we show in mice that the short isoform of a critical regulator of HSCs, Prdm16 (refs 4, 5), induces mitofusin 2 (Mfn2), a protein involved in mitochondrial fusion and in tethering of mitochondria to the endoplasmic reticulum. Overexpression and deletion studies …
Here we show in mice that the short isoform of a critical regulator of HSCs, Prdm16 (refs 4, 5), induces mitofusin 2 (Mfn2), a …
[Mitofusin 2 and mitochondrial dynamics in norm and pathology].
Kawalec M, Beręsewicz M, Zabłocki K, Zabłocka B. Kawalec M, et al. Postepy Biochem. 2016;62(2):149-157. Postepy Biochem. 2016. PMID: 28132466 Free article. Review. Polish.
Mutations within mitofusin 2-encoding gene are a cause of Charcot-Marie-Tooh 2A - type neuropathies while an affected expression of this protein seems to be related to neoplasia, type 2 diabetes, or vascular hyperplasia. Numerous experimental data confirm ple …
Mutations within mitofusin 2-encoding gene are a cause of Charcot-Marie-Tooh 2A - type neuropathies while an affected expressi …
Highlighting the endoplasmic reticulum-mitochondria connection: Focus on Mitofusin 2.
Filadi R, Greotti E, Pizzo P. Filadi R, et al. Pharmacol Res. 2018 Feb;128:42-51. doi: 10.1016/j.phrs.2018.01.003. Epub 2018 Jan 5. Pharmacol Res. 2018. PMID: 29309902 Review.
By proteinaceous tethers, specialized membrane domains of the ER are tightly associated with the outer membrane of mitochondria, allowing the assembly of signaling platforms where different cell functions take place or are modulated, such as lipid biosynthesis, Ca(2+) home …
By proteinaceous tethers, specialized membrane domains of the ER are tightly associated with the outer membrane of mitochondria, allowing th …
Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Li YJ, Cao YL, Feng JX, Qi Y, Meng S, Yang JF, Zhong YT, Kang S, Chen X, Lan L, Luo L, Yu B, Chen S, Chan DC, Hu J, Gao S. Li YJ, et al. Nat Commun. 2019 Oct 29;10(1):4914. doi: 10.1038/s41467-019-12912-0. Nat Commun. 2019. PMID: 31664033 Free PMC article.
Mitofusin-2 (MFN2) is a dynamin-like GTPase that plays a central role in regulating mitochondrial fusion and cell metabolism. ...CMT2A-related mutations, mapping to different functional zones of MFN2, lead to changes in GTP hydrolysis and homo/hetero-association abi
Mitofusin-2 (MFN2) is a dynamin-like GTPase that plays a central role in regulating mitochondrial fusion and cell metabolism.
971 results
You have reached the last page of results. A maximum of 10,000 results are available.
Jump to page
Feedback