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Year Number of Results
1971 1
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1982 3
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1985 3
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1988 11
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1995 34
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2002 29
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2004 33
2005 39
2006 30
2007 38
2008 36
2009 35
2010 37
2011 41
2012 51
2013 61
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2015 35
2016 34
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1,178 results

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Page 1
A mitotic chromatin phase transition prevents perforation by microtubules.
Schneider MWG, Gibson BA, Otsuka S, Spicer MFD, Petrovic M, Blaukopf C, Langer CCH, Batty P, Nagaraju T, Doolittle LK, Rosen MK, Gerlich DW. Schneider MWG, et al. Nature. 2022 Sep;609(7925):183-190. doi: 10.1038/s41586-022-05027-y. Epub 2022 Aug 3. Nature. 2022. PMID: 35922507 Free PMC article.
Although condensin confers mechanical resistance to spindle pulling forces(14-16), it is not known how histone deacetylation affects material properties and, as a consequence, segregation mechanics of mitotic chromosomes. Here we show how global histone deacetylation at th …
Although condensin confers mechanical resistance to spindle pulling forces(14-16), it is not known how histone deacetylation affects materia …
Extensive mutual influences of SMC complexes shape 3D genome folding.
Zhao H, Shu L, Qin S, Lyu F, Liu F, Lin E, Xia S, Wang B, Wang M, Shan F, Lin Y, Zhang L, Gu Y, Blobel GA, Huang K, Zhang H. Zhao H, et al. Nature. 2025 Apr;640(8058):543-553. doi: 10.1038/s41586-025-08638-3. Epub 2025 Feb 26. Nature. 2025. PMID: 40011778 Free PMC article.
Mammalian genomes are folded through the distinct actions of structural maintenance of chromosome (SMC) complexes, which include the chromatin loop-extruding cohesin (extrusive cohesin), the sister chromatid cohesive cohesin and the mitotic chromosome-associated condensins …
Mammalian genomes are folded through the distinct actions of structural maintenance of chromosome (SMC) complexes, which include the chromat …
Regulation of Mitotic Exit by Cell Cycle Checkpoints: Lessons From Saccharomyces cerevisiae.
Matellán L, Monje-Casas F. Matellán L, et al. Genes (Basel). 2020 Feb 12;11(2):195. doi: 10.3390/genes11020195. Genes (Basel). 2020. PMID: 32059558 Free PMC article. Review.
To this end, cells have developed highly elaborated checkpoints that halt mitotic progression when problems in DNA integrity or chromosome segregation arise, providing them with time to fix these issues before advancing further into the cell cycle. Remarkably …
To this end, cells have developed highly elaborated checkpoints that halt mitotic progression when problems in DNA integrity or chrom …
The mitotic cell cycle-associated nomogram predicts overall survival in lung adenocarcinoma.
He X, Zhou H, Huang Q, Li Y. He X, et al. Cancer Med. 2023 Dec;12(23):21519-21530. doi: 10.1002/cam4.6676. Epub 2023 Nov 6. Cancer Med. 2023. PMID: 37930238 Free PMC article.
BACKGROUND: This study aimed to develop a prognostic model for lung adenocarcinoma (LUAD) associated with mitotic cell cycle. The model will predict the probability of survival at different time points and serve as a reference tool to evaluate the effectivene …
BACKGROUND: This study aimed to develop a prognostic model for lung adenocarcinoma (LUAD) associated with mitotic cell cycl …
Contribution of caspase(s) to the cell cycle regulation at mitotic phase.
Hashimoto T, Kikkawa U, Kamada S. Hashimoto T, et al. PLoS One. 2011 Mar 30;6(3):e18449. doi: 10.1371/journal.pone.0018449. PLoS One. 2011. PMID: 21479177 Free PMC article.
By using HeLa.S-Fucci (fluorescent ubiquitination-based cell cycle indicator) cells, the prevention of the cell proliferation by caspase inhibitors induced cell cycle arrest at mitotic phase accompanying the accumulation of the sub …
By using HeLa.S-Fucci (fluorescent ubiquitination-based cell cycle indicator) cells, the prevention of the cell prolife …
p21(WAF1/CIP1) inhibits cell cycle progression but not G2/M-phase transition following methylmercury exposure.
Mendoza MA, Ponce RA, Ou YC, Faustman EM. Mendoza MA, et al. Toxicol Appl Pharmacol. 2002 Jan 15;178(2):117-25. doi: 10.1006/taap.2001.9267. Toxicol Appl Pharmacol. 2002. PMID: 11814332
Prenatal MeHg exposure is associated with reduced brain size and weight and a reduced number of neurons, which have been associated with impaired cell proliferation. We evaluate the role of p21, a cell cycle protein involved in the G1- and G2-phase che …
Prenatal MeHg exposure is associated with reduced brain size and weight and a reduced number of neurons, which have been associated with imp …
TRAP1 controls cell cycle G2-M transition through the regulation of CDK1 and MAD2 expression/ubiquitination.
Sisinni L, Maddalena F, Condelli V, Pannone G, Simeon V, Li Bergolis V, Lopes E, Piscazzi A, Matassa DS, Mazzoccoli C, Nozza F, Lettini G, Amoroso MR, Bufo P, Esposito F, Landriscina M. Sisinni L, et al. J Pathol. 2017 Sep;243(1):123-134. doi: 10.1002/path.4936. Epub 2017 Aug 9. J Pathol. 2017. PMID: 28678347
Regulation of tumour cell proliferation by molecular chaperones is still a complex issue. Here, the role of the HSP90 molecular chaperone TRAP1 in cell cycle regulation was investigated in a wide range of human breast, colorectal, and lung carcinoma cell …
Regulation of tumour cell proliferation by molecular chaperones is still a complex issue. Here, the role of the HSP90 molecular chape …
Cell cycle-regulated proteolysis of mitotic target proteins.
Bastians H, Topper LM, Gorbsky GL, Ruderman JV. Bastians H, et al. Mol Biol Cell. 1999 Nov;10(11):3927-41. doi: 10.1091/mbc.10.11.3927. Mol Biol Cell. 1999. PMID: 10564281 Free PMC article.
The ubiquitin-dependent proteolysis of mitotic cyclin B, which is catalyzed by the anaphase-promoting complex/cyclosome (APC/C) and ubiquitin-conjugating enzyme H10 (UbcH10), begins around the time of the metaphase-anaphase transition and continues through G1 pha …
The ubiquitin-dependent proteolysis of mitotic cyclin B, which is catalyzed by the anaphase-promoting complex/cyclosome (APC/C) and u …
Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G(2)/M-phase transition.
Shen Y, Sherman JW, Chen X, Wang R. Shen Y, et al. J Biol Chem. 2018 Apr 6;293(14):5185-5199. doi: 10.1074/jbc.RA117.001379. Epub 2018 Feb 21. J Biol Chem. 2018. PMID: 29467227 Free PMC article.
The cell-cycle G(2)/M-phase transition is controlled by mitotic cyclin-dependent kinase complex (CDC2-cyclin B), which is inactivated by WEE1 family protein kinases and activated by the opposing phosphatase CDC25C. ...These findings suggest that …
The cell-cycle G(2)/M-phase transition is controlled by mitotic cyclin-dependent kinase complex (CDC2-cyc …
HIV-1 VPR modulates cell cycle G2/M transition through an alternative cellular mechanism other than the classic mitotic checkpoints.
Elder RT, Benko Z, Zhao Y. Elder RT, et al. Front Biosci. 2002 Feb 1;7:d349-57. doi: 10.2741/elder. Front Biosci. 2002. PMID: 11815283 Review.
HIV-1 Vpr induces cell cycle G2/M arrest in both human and fission yeast cells, suggesting a highly conserved activity of this viral protein. ...We have compared the classic DNA-damage and DNA-replication checkpoint controls of the cell cycle G2/M t …
HIV-1 Vpr induces cell cycle G2/M arrest in both human and fission yeast cells, suggesting a highly conserved activity of this …
1,178 results