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Kratom (Mitragyna speciosa): Friend or Foe?

Sethi R, Hoang N, Ravishankar DA, McCracken M, Manzardo AM. Sethi R, et al. Prim Care Companion CNS Disord. 2020 Jan 30;22(1):19nr02507. doi: 10.4088/PCC.19nr02507. Prim Care Companion CNS Disord. 2020. PMID: 31999896 Free article. Review.

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Kratom (Mitragyna speciosa): worldwide issues.

Ramanathan S, McCurdy CR. Ramanathan S, et al. Curr Opin Psychiatry. 2020 Jul;33(4):312-318. doi: 10.1097/YCO.0000000000000621. Curr Opin Psychiatry. 2020. PMID: 32452943 Review.

PURPOSE OF REVIEW: To inform readers about the increasingly popular Western dietary supplement, kratom (Mitragyna speciosa) and how the products are available in the Western world compared with traditional Southeast Asian use. ...

PURPOSE OF REVIEW: To inform readers about the increasingly popular Western dietary supplement, kratom (Mitragyna speciosa) an …

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Kratom (Mitragyna Speciosa) Liver Injury: A Comprehensive Review.

Schimmel J, Dart RC. Schimmel J, et al. Drugs. 2020 Feb;80(3):263-283. doi: 10.1007/s40265-019-01242-6. Drugs. 2020. PMID: 31919755 Review.

Kratom (Mitragyna speciosa) leaves contain the mu opioid partial agonists mitragynine and 7-hydroxymitragynine. ...

Kratom (Mitragyna speciosa) leaves contain the mu opioid partial agonists mitragynine and 7-hydroxymitragynine. ...

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Mitragyna speciosa: Clinical, Toxicological Aspects and Analysis in Biological and Non-Biological Samples.

Meireles V, Rosado T, Barroso M, Soares S, Gonçalves J, Luís Â, Caramelo D, Simão AY, Fernández N, Duarte AP, Gallardo E. Meireles V, et al. Medicines (Basel). 2019 Mar 4;6(1):35. doi: 10.3390/medicines6010035. Medicines (Basel). 2019. PMID: 30836609 Free PMC article. Review.

The abuse of psychotropic substances is a well-known phenomenon, and many of them are usually associated with ancestral traditions and home remedies. This is the case of Mitragyna speciosa (kratom), a tropical tree used to improve work performance and to withstand g …

The abuse of psychotropic substances is a well-known phenomenon, and many of them are usually associated with ancestral traditions and home …

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Differentiation of Mitragyna speciosa, a narcotic plant, from allied Mitragyna species using DNA barcoding-high-resolution melting (Bar-HRM) analysis.

Tungphatthong C, Urumarudappa SKJ, Awachai S, Sooksawate T, Sukrong S. Tungphatthong C, et al. Sci Rep. 2021 Mar 24;11(1):6738. doi: 10.1038/s41598-021-86228-9. Sci Rep. 2021. PMID: 33762644 Free PMC article.

Mitragyna speciosa (Korth.) Havil. [MS], or "kratom" in Thai, is the only narcotic species among the four species of Mitragyna in Thailand, which also include Mitragyna diversifolia (Wall. ex G. ...In this study, DNA barcoding combined with high-resolu …

Mitragyna speciosa (Korth.) Havil. [MS], or "kratom" in Thai, is the only narcotic species among the four species of Mitrag …

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Activity of Mitragyna speciosa ("Kratom") Alkaloids at Serotonin Receptors.

León F, Obeng S, Mottinelli M, Chen Y, King TI, Berthold EC, Kamble SH, Restrepo LF, Patel A, Gamez-Jimenez LR, Lopera-Londoño C, Hiranita T, Sharma A, Hampson AJ, Canal CE, McMahon LR, McCurdy CR. León F, et al. J Med Chem. 2021 Sep 23;64(18):13510-13523. doi: 10.1021/acs.jmedchem.1c00726. Epub 2021 Sep 1. J Med Chem. 2021. PMID: 34467758

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A Review on the Antinociceptive Effects of Mitragyna speciosa and Its Derivatives on Animal Model.

Chin KY, Mark-Lee WF. Chin KY, et al. Curr Drug Targets. 2018;19(12):1359-1365. doi: 10.2174/1389450118666170925154025. Curr Drug Targets. 2018. PMID: 28950813 Review.

Mitragyna speciosa is a tropical plant with narcotic effects. The antinociceptive effects of its crude extracts, bioactive compounds and structurally modified derivatives have been examined in rodent models. ...In conclusion, M speciosa derivatives can offer …

Mitragyna speciosa is a tropical plant with narcotic effects. The antinociceptive effects of its crude extracts, bioactive com …

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The Mitragyna speciosa (Kratom) Genome: a resource for data-mining potent pharmaceuticals that impact human health.

Brose J, Lau KH, Dang TTT, Hamilton JP, Martins LDV, Hamberger B, Hamberger B, Jiang J, O'Connor SE, Buell CR. Brose J, et al. G3 (Bethesda). 2021 Apr 15;11(4):jkab058. doi: 10.1093/g3journal/jkab058. G3 (Bethesda). 2021. PMID: 33677570 Free PMC article.

Mitragyna speciosa (kratom) produces numerous compounds with pharmaceutical properties including the production of bioactive monoterpene indole and oxindole alkaloids. Using a linked-read approach, a 1,122,519,462 bp draft assembly of M. speciosa "Rifat" was …

Mitragyna speciosa (kratom) produces numerous compounds with pharmaceutical properties including the production of bioactive m …

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Mitragyna speciosa: Balancing Potential Medical Benefits and Abuse.

Halpenny GM. Halpenny GM. ACS Med Chem Lett. 2017 Aug 8;8(9):897-899. doi: 10.1021/acsmedchemlett.7b00298. eCollection 2017 Sep 14. ACS Med Chem Lett. 2017. PMID: 28947930 Free PMC article.

Mitragyna speciosa, also known as kratom, has the potential meet the need for pain medications that lack the addictiveness and overdose risk of classical opioid analgesics, such as morphine. ...Thus, there is a need to balance the potential medical benefits and abus …

Mitragyna speciosa, also known as kratom, has the potential meet the need for pain medications that lack the addictiveness and …

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Kratom (Mitragyna speciosa)-Induced Hepatitis.

Allison DR, Mubarak M, Sharma N, Rao DS. Allison DR, et al. ACG Case Rep J. 2022 Apr 7;9(4):e00715. doi: 10.14309/crj.0000000000000715. eCollection 2022 Apr. ACG Case Rep J. 2022. PMID: 35399621 Free PMC article.

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