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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1980 1
1983 1
1984 1
1985 2
1986 4
1987 4
1988 3
1989 2
1990 3
1991 2
1992 3
1993 4
1994 3
1995 5
1996 1
1997 4
1998 6
1999 1
2000 6
2001 3
2002 8
2003 7
2004 8
2005 14
2006 7
2007 14
2008 11
2009 21
2010 19
2011 25
2012 22
2013 30
2014 34
2015 36
2016 35
2017 34
2018 46
2019 58
2020 62
2021 67
2022 61
2023 69
2024 96
2025 105
2026 85

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933 results

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Page 1
Nociplastic pain: towards an understanding of prevalent pain conditions.
Fitzcharles MA, Cohen SP, Clauw DJ, Littlejohn G, Usui C, Häuser W. Fitzcharles MA, et al. Lancet. 2021 May 29;397(10289):2098-2110. doi: 10.1016/S0140-6736(21)00392-5. Lancet. 2021. PMID: 34062144 Review.
The mechanisms that underlie this type of pain are not entirely understood, but it is thought that augmented CNS pain and sensory processing and altered pain modulation play prominent roles. ...This type of pain can occur in isolation, as often …
The mechanisms that underlie this type of pain are not entirely understood, but it is thought that augmented CNS pain a …
Mechanisms and treatment of opioid-induced pruritus: Peripheral and central pathways.
Okutani H, Lo Vecchio S, Arendt-Nielsen L. Okutani H, et al. Eur J Pain. 2024 Feb;28(2):214-230. doi: 10.1002/ejp.2180. Epub 2023 Aug 31. Eur J Pain. 2024. PMID: 37650457 Review.
CONCLUSION: The use of a multimodal analgesic treatment regimen combined with a mixed antagonist and kappa agonists, especially mu-opioid antagonists, and kappa-opioid agonists, seems to be the current best treatment modality for the management of opioid-indu …
CONCLUSION: The use of a multimodal analgesic treatment regimen combined with a mixed antagonist and kappa agonists, especiall …
Occlusal interventions for managing temporomandibular disorders.
Singh BP, Singh N, Jayaraman S, Kirubakaran R, Joseph S, Muthu MS, Jivnani H, Hua F. Singh BP, et al. Cochrane Database Syst Rev. 2024 Sep 16;9(9):CD012850. doi: 10.1002/14651858.CD012850.pub2. Cochrane Database Syst Rev. 2024. PMID: 39282765 Free PMC article.
SELECTION CRITERIA: We included randomised controlled trials (RCTs) of occlusal interventions (splints or adjustment) for managing TMD compared with no treatment, placebo, occlusal splint with a different mechanism of action, or other active treatments. ...Th …
SELECTION CRITERIA: We included randomised controlled trials (RCTs) of occlusal interventions (splints or adjustment) for managing TMD compa …
Mechanisms and Preventative Strategies for Persistent Pain following Knee and Hip Joint Replacement Surgery: A Narrative Review.
Murphy J, Pak S, Shteynman L, Winkeler I, Jin Z, Kaczocha M, Bergese SD. Murphy J, et al. Int J Mol Sci. 2024 Apr 26;25(9):4722. doi: 10.3390/ijms25094722. Int J Mol Sci. 2024. PMID: 38731944 Free PMC article. Review.
The identification of risk factors for CPSP following TKA and THA is challenging but essential for targeted preventative therapy. Recent meta-analyses and individual studies highlight associations between elevated state anxiety, depression scores, preoperative pain, …
The identification of risk factors for CPSP following TKA and THA is challenging but essential for targeted preventative therapy. Rec …
Sex, gender, and pain: a review of recent clinical and experimental findings.
Fillingim RB, King CD, Ribeiro-Dasilva MC, Rahim-Williams B, Riley JL 3rd. Fillingim RB, et al. J Pain. 2009 May;10(5):447-85. doi: 10.1016/j.jpain.2008.12.001. J Pain. 2009. PMID: 19411059 Free PMC article. Review.
The evidence regarding sex differences in laboratory measures of endogenous pain modulation is mixed, as are findings from studies using functional brain imaging to ascertain sex differences in pain-related cerebral activation. Also inconsistent are findings …
The evidence regarding sex differences in laboratory measures of endogenous pain modulation is mixed, as are findings from stu …
Reduction of Chronic Primary Low Back Pain by Spinal Manipulative Therapy is Accompanied by Decreases in Segmental Mechanical Hyperalgesia and Pain Catastrophizing: A Randomized Placebo-controlled Dual-blind Mixed Experimental Trial.
Gevers-Montoro C, Romero-Santiago B, Medina-García I, Larranaga-Arzamendi B, Álvarez-Gálovich L, Ortega-De Mues A, Piché M. Gevers-Montoro C, et al. J Pain. 2024 Aug;25(8):104500. doi: 10.1016/j.jpain.2024.02.014. Epub 2024 Feb 16. J Pain. 2024. PMID: 38369221 Free article. Clinical Trial.
Previous studies have shown that spinal manipulative therapy (SMT) is effective in relieving CPLBP, but the underlying mechanisms remain elusive. This randomized placebo-controlled dual-blind mixed experimental trial (NCT05162924) aimed to investigate the eff …
Previous studies have shown that spinal manipulative therapy (SMT) is effective in relieving CPLBP, but the underlying mechanisms …
Identifying risk factors for chronic postsurgical pain and preventive measures: a comprehensive update.
Pergolizzi JV Jr, LeQuang JA, Magnusson P, Varrassi G. Pergolizzi JV Jr, et al. Expert Rev Neurother. 2023 Jul-Dec;23(12):1297-1310. doi: 10.1080/14737175.2023.2284872. Epub 2023 Dec 15. Expert Rev Neurother. 2023. PMID: 37999989 Review.
Multimodal pain care solves two pain problems. First, CPSP tends to be different types of pain that occur together in something called a 'mixed pain syndrome.' Multimodal pain treatment uses more than one agent with different me …
Multimodal pain care solves two pain problems. First, CPSP tends to be different types of pain that occur together in s …
Mixed-mechanism analgesics for mixed pain.
Raffa RB. Raffa RB. Front Med (Lausanne). 2025 Nov 26;12:1717207. doi: 10.3389/fmed.2025.1717207. eCollection 2025. Front Med (Lausanne). 2025. PMID: 41384104 Free PMC article.
This dichotomy is reflected in the very definitions or descriptions of mixed pain as a type of pain that manifests with symptoms that include those indicative of both nociceptive pain (viz., pain arising from tissue damage) and of neuropathic …
This dichotomy is reflected in the very definitions or descriptions of mixed pain as a type of pain that manifests with …
Intravenous Lidocaine for the Management of Chronic Pain: A Narrative Review of Randomized Clinical Trials.
Onyeaka H, Adeola J, Xu R, Pappy AL, Adeola S, Smucker M, Chang A, Fraga A, Ufondu W, Osman M, Hasoon J, Orhurhu VJ. Onyeaka H, et al. Psychopharmacol Bull. 2024 Jul 8;54(3):73-96. doi: 10.64719/pb.4495. Psychopharmacol Bull. 2024. PMID: 38993659 Free PMC article. Review.
Available treatments have only resulted in relatively modest efficacy. Thus, novel therapeutic treatments with different mechanisms have recently generated empirical interest. ...CONCLUSION: Lidocaine may be a promising pharmacologic solution for chronic p …
Available treatments have only resulted in relatively modest efficacy. Thus, novel therapeutic treatments with different me …
The Role of the Cervical Spine in Dizziness.
Treleaven J. Treleaven J. J Neurol Phys Ther. 2024 Oct 1;48(4):1-10. doi: 10.1097/NPT.0000000000000491. Epub 2024 Sep 17. J Neurol Phys Ther. 2024. PMID: 39146225
The neck can be implicated in dizziness via several, separate, discreet mechanisms. Proprioceptive cervicogenic dizziness (CGD) is the most common and reflects the cervical spine's important role, along with visual and vestibular input, for sensorimotor control. ...Despite …
The neck can be implicated in dizziness via several, separate, discreet mechanisms. Proprioceptive cervicogenic dizziness (CGD) is th …
933 results