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Clostridium butyricum MIYAIRI 588 as Adjunctive Therapy for Treatment-Resistant Major Depressive Disorder: A Prospective Open-Label Trial.
Miyaoka T, Kanayama M, Wake R, Hashioka S, Hayashida M, Nagahama M, Okazaki S, Yamashita S, Miura S, Miki H, Matsuda H, Koike M, Izuhara M, Araki T, Tsuchie K, Azis IA, Arauchi R, Abdullah RA, Oh-Nishi A, Horiguchi J. Miyaoka T, et al. Clin Neuropharmacol. 2018 Sep/Oct;41(5):151-155. doi: 10.1097/WNF.0000000000000299. Clin Neuropharmacol. 2018. PMID: 30234616 Clinical Trial.
We performed a prospective study to evaluate the effects of Clostridium butyricum MIYAIRI 588 (CBM588). METHODS: This was an 8-week open-label study to evaluate the efficacy and safety of CBM588 in combination with antidepressants in adult patients diagnosed with TR …
We performed a prospective study to evaluate the effects of Clostridium butyricum MIYAIRI 588 (CBM588). METHODS: This was an 8 …
Clostridium butyricum MIYAIRI 588 Modifies Bacterial Composition under Antibiotic-Induced Dysbiosis for the Activation of Interactions via Lipid Metabolism between the Gut Microbiome and the Host.
Ariyoshi T, Hagihara M, Tomono S, Eguchi S, Minemura A, Miura D, Oka K, Takahashi M, Yamagishi Y, Mikamo H. Ariyoshi T, et al. Biomedicines. 2021 Aug 22;9(8):1065. doi: 10.3390/biomedicines9081065. Biomedicines. 2021. PMID: 34440269 Free PMC article.
The gut microbiome is closely related to gut metabolic functions, and the gut microbiome and host metabolic functions affect each other. Clostridium butyricum MIYAIRI 588 (CBM 588) upregulates protectin D1 production in host colon tissue following G protein-c …
The gut microbiome is closely related to gut metabolic functions, and the gut microbiome and host metabolic functions affect each other. Clo …
Clostridium butyricum MIYAIRI 588-Induced Protectin D1 Has an Anti-inflammatory Effect on Antibiotic-Induced Intestinal Disorder.
Ariyoshi T, Hagihara M, Eguchi S, Fukuda A, Iwasaki K, Oka K, Takahashi M, Yamagishi Y, Mikamo H. Ariyoshi T, et al. Front Microbiol. 2020 Oct 30;11:587725. doi: 10.3389/fmicb.2020.587725. eCollection 2020. Front Microbiol. 2020. PMID: 33193245 Free PMC article.
Previously, we showed that the administration of Clostridium butyricum MIYAIRI 588 (CBM 588) upregulated protectin D1, an anti-inflammatory lipid metabolite, in colon tissue under antibiotic therapy. ...We provide new insights into CBM 588-mediated lip …
Previously, we showed that the administration of Clostridium butyricum MIYAIRI 588 (CBM 588) upregulated protectin D1, …
Clostridium butyricum MIYAIRI 588 Increases the Lifespan and Multiple-Stress Resistance of Caenorhabditis elegans.
Kato M, Hamazaki Y, Sun S, Nishikawa Y, Kage-Nakadai E. Kato M, et al. Nutrients. 2018 Dec 5;10(12):1921. doi: 10.3390/nu10121921. Nutrients. 2018. PMID: 30563064 Free PMC article.
Clostridium butyricum MIYAIRI 588 (CBM 588), one of the probiotic bacterial strains used for humans and domestic animals, has been reported to exert a variety of beneficial health effects. ...When adult C. elegans were fed a standard diet of Escherichia coli …
Clostridium butyricum MIYAIRI 588 (CBM 588), one of the probiotic bacterial strains used for humans and domestic animal …
The impact of probiotic Clostridium butyricum MIYAIRI 588 on murine gut metabolic alterations.
Hagihara M, Yamashita R, Matsumoto A, Mori T, Inagaki T, Nonogaki T, Kuroki Y, Higashi S, Oka K, Takahashi M, Mikamo H. Hagihara M, et al. J Infect Chemother. 2019 Aug;25(8):571-577. doi: 10.1016/j.jiac.2019.02.008. Epub 2019 May 14. J Infect Chemother. 2019. PMID: 31101528
INTRODUCTION: Clostridium butyricum MIYAIRI 588 (CBM 588) is a probiotic bacterium used in antidiarrheal medicine in Japan. ...CLDM, 2. CBM 588, 3. CBM 588 + CLDM, 4. water) for 4 days. Fecal samples were collected to extract DNA for metagenomic …
INTRODUCTION: Clostridium butyricum MIYAIRI 588 (CBM 588) is a probiotic bacterium used in antidiarrheal medicine in Ja …
The impact of Clostridium butyricum MIYAIRI 588 on the murine gut microbiome and colonic tissue.
Hagihara M, Yamashita R, Matsumoto A, Mori T, Kuroki Y, Kudo H, Oka K, Takahashi M, Nonogaki T, Yamagishi Y, Mikamo H. Hagihara M, et al. Anaerobe. 2018 Dec;54:8-18. doi: 10.1016/j.anaerobe.2018.07.012. Epub 2018 Aug 1. Anaerobe. 2018. PMID: 30076897
BACKGROUND: Clostridium butyricum MIYAIRI 588 (CBM 588) is a probiotic bacterium that is used as an anti-diarrheal medicine in Japan. However, the impact of this probiotic on the gut microbiome has not been fully elucidated, especially, when used with antimic …
BACKGROUND: Clostridium butyricum MIYAIRI 588 (CBM 588) is a probiotic bacterium that is used as an anti-diarrheal medi …
Association of Probiotic Clostridium butyricum Therapy with Survival and Response to Immune Checkpoint Blockade in Patients with Lung Cancer.
Tomita Y, Ikeda T, Sakata S, Saruwatari K, Sato R, Iyama S, Jodai T, Akaike K, Ishizuka S, Saeki S, Sakagami T. Tomita Y, et al. Cancer Immunol Res. 2020 Oct;8(10):1236-1242. doi: 10.1158/2326-6066.CIR-20-0051. Epub 2020 Jul 14. Cancer Immunol Res. 2020. PMID: 32665261
Gut microbiota is becoming an attractive therapeutic target for cancer. The Clostridium butyricum MIYAIRI 588 strain is a probiotic therapy used to improve symptoms related to antibiotic-induced dysbiosis in Japan. ...
Gut microbiota is becoming an attractive therapeutic target for cancer. The Clostridium butyricum MIYAIRI 588 strain is a prob …
Clostridium butyricum miyairi 588 has preventive effects on chronic social defeat stress-induced depressive-like behaviour and modulates microglial activation in mice.
Tian T, Xu B, Qin Y, Fan L, Chen J, Zheng P, Gong X, Wang H, Bai M, Pu J, Lu J, Zhou W, Zhao L, Yang D, Xie P. Tian T, et al. Biochem Biophys Res Commun. 2019 Aug 20;516(2):430-436. doi: 10.1016/j.bbrc.2019.06.053. Epub 2019 Jun 18. Biochem Biophys Res Commun. 2019. PMID: 31227215
However, the potential role of Clostridium butyricum in modulating the gut-brain-axis remains unknown. Here, we applied the commercial Clostridium butyricum Miyairi 588 (CBM588) strain to assess psychological behavioural alterations in mice exposed to chronic social …
However, the potential role of Clostridium butyricum in modulating the gut-brain-axis remains unknown. Here, we applied the commercial Clost …
Effect of Clostridium butyricum on Gastrointestinal Infections.
Ariyoshi T, Hagihara M, Takahashi M, Mikamo H. Ariyoshi T, et al. Biomedicines. 2022 Feb 18;10(2):483. doi: 10.3390/biomedicines10020483. Biomedicines. 2022. PMID: 35203691 Free PMC article. Review.
Owing to its preventive and ameliorative effects on gastrointestinal infections, C. butyricum MIYAIRI 588 (CBM 588) has been used as a probiotic in clinical and veterinary medicine for decades. This review summarizes the effects of C. butyricum, including CBM …
Owing to its preventive and ameliorative effects on gastrointestinal infections, C. butyricum MIYAIRI 588 (CBM 588) has …
Supplemental Clostridium butyricum MIYAIRI 588 Affects Intestinal Bacterial Composition of Finishing Pigs.
Hirata M, Matsuoka M, Hashimoto T, Oura T, Ohnuki Y, Yoshida C, Minemura A, Miura D, Oka K, Takahashi M, Morimatsu F. Hirata M, et al. Microbes Environ. 2022;37(3):ME22011. doi: 10.1264/jsme2.ME22011. Microbes Environ. 2022. PMID: 36155363 Free PMC article.
Therefore, we herein investigated the effects of C. butyricum MIYAIRI 588 (CBM588) on the gut microbiota of finishing pigs. 16S rRNA gene sequencing was performed using fecal samples and ileal, cecal, and colonic contents collected after slaughtering. ...
Therefore, we herein investigated the effects of C. butyricum MIYAIRI 588 (CBM588) on the gut microbiota of finishing pigs. 16 …
40 results