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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1954 1
1955 1
1960 1
1961 1
1963 2
1964 1
1965 1
1986 2
1987 1
1988 1
1989 2
1990 3
1991 6
1992 3
1993 11
1994 9
1995 10
1996 11
1997 11
1998 25
1999 20
2000 25
2001 29
2002 47
2003 54
2004 75
2005 84
2006 95
2007 111
2008 124
2009 124
2010 148
2011 105
2012 130
2013 115
2014 117
2015 115
2016 108
2017 101
2018 101
2019 99
2020 104
2021 120
2022 94
2023 87
2024 90
2025 102
2026 47

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2,372 results

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Page 1
Modafinil, an atypical CNS stimulant?
Hersey M, Tanda G. Hersey M, et al. Adv Pharmacol. 2024;99:287-326. doi: 10.1016/bs.apha.2023.10.006. Epub 2023 Nov 22. Adv Pharmacol. 2024. PMID: 38467484 Free PMC article.
Modafinil is a central nervous system stimulant approved for the treatment of narcolepsy and sleep disorders. ...However, modafinil is unique in that only a few cases of dependence on this drug have been reported, as compared to other psychostimulants. ...
Modafinil is a central nervous system stimulant approved for the treatment of narcolepsy and sleep disorders. ...However, modafini …
Modafinil for poststroke patients: A systematic review.
Pacheco RL, Latorraca COC, da Silva LDGM, Ferreira DBGM, Fernandes CAA, Hosni ND, Cabrera Martimbianco AL, Vianna Pachito D, Riera R. Pacheco RL, et al. Int J Clin Pract. 2019 Feb;73(2):e13295. doi: 10.1111/ijcp.13295. Epub 2018 Dec 11. Int J Clin Pract. 2019. PMID: 30444561
INTRODUCTION: Stroke is a major cause of death and disability worldwide. The use of modafinil, a wakefulness-promoting agent, is hypothesised to benefit stroke patients. METHODS: We performed a systematic review in accordance with the Cochrane Handbook for Systematic Revie …
INTRODUCTION: Stroke is a major cause of death and disability worldwide. The use of modafinil, a wakefulness-promoting agent, is hypo …
Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine.
Repantis D, Bovy L, Ohla K, Kühn S, Dresler M. Repantis D, et al. Psychopharmacology (Berl). 2021 Feb;238(2):441-451. doi: 10.1007/s00213-020-05691-w. Epub 2020 Nov 17. Psychopharmacology (Berl). 2021. PMID: 33201262 Free PMC article. Clinical Trial.
METHODS: We conducted a pilot study with three arms in which male participants received placebo and one of three stimulants (caffeine, methylphenidate, modafinil) and assessed cognitive performance with a test battery that captures various cognitive domains. ...Methylpheni …
METHODS: We conducted a pilot study with three arms in which male participants received placebo and one of three stimulants (caffeine, methy …
Modafinil and orexin system: interactions and medico-legal considerations.
Salerno M, Villano I, Nicolosi D, Longhitano L, Loreto C, Lovino A, Sessa F, Polito AN, Monda V, Chieffi S, Messina A, Monda M, Zammit C, Tafuri D, Messina G, Carotenuto M. Salerno M, et al. Front Biosci (Landmark Ed). 2019 Jan 1;24(3):564-575. doi: 10.2741/4736. Front Biosci (Landmark Ed). 2019. PMID: 30468674 Free article. Review.
Modafinil (Mo) is increasingly being used as an enhancement drug rather than for its therapeutic effects. ...
Modafinil (Mo) is increasingly being used as an enhancement drug rather than for its therapeutic effects. ...
Modafinil Versus Amphetamine-Dextroamphetamine For Idiopathic Hypersomnia and Narcolepsy Type 2: A Randomized, Blinded, Non-inferiority Trial.
Trotti LM, Blake T, Hoque R, Rye DB, Sharma S, Bliwise DL. Trotti LM, et al. CNS Drugs. 2024 Nov;38(11):909-920. doi: 10.1007/s40263-024-01122-y. Epub 2024 Sep 21. CNS Drugs. 2024. PMID: 39306601 Free PMC article. Clinical Trial.
We performed a randomized, fully blinded, noninferiority trial of modafinil versus amphetamine-dextroamphetamine in these disorders. METHODS: Forty-four adults were randomized to modafinil or amphetamine-dextroamphetamine, individually titrated to a maximum of mo …
We performed a randomized, fully blinded, noninferiority trial of modafinil versus amphetamine-dextroamphetamine in these disorders. …
Repurposing of modafinil as an anti-inflammatory drug: a systematic review of experimental studies.
Amini MJ, Seighali N, Arabazadeh Bahri R, Ala M, Mohammad Jafari R, Dehpour AR. Amini MJ, et al. Naunyn Schmiedebergs Arch Pharmacol. 2025 Nov;398(11):15599-15609. doi: 10.1007/s00210-025-03964-9. Epub 2025 May 13. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 40358683
Previous studies suggested the anti-inflammatory properties of modafinil. This study aimed to review the current literature to provide a comprehensive insight into the anti-inflammatory uses of modafinil in experimental studies. ...Current evidence supports that …
Previous studies suggested the anti-inflammatory properties of modafinil. This study aimed to review the current literature to provid …
Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review.
Gagnon DJ, Leclerc AM, Riker RR, Brown CS, May T, Nocella K, Cote J, Eldridge A, Seder DB. Gagnon DJ, et al. Neurocrit Care. 2020 Aug;33(1):283-297. doi: 10.1007/s12028-020-00977-5. Neurocrit Care. 2020. PMID: 32394130
Modafinil was initiated 170 (17, 496) days post-stroke, with initial and final daily doses of 100 (100, 350) mg/day and 200 (100, 350) mg/day, respectively. ...A positive response in at least one clinical effectiveness measure was reported in 70% of amantadine publications …
Modafinil was initiated 170 (17, 496) days post-stroke, with initial and final daily doses of 100 (100, 350) mg/day and 200 (100, 350 …
Modafinil Treatment of Cocaine Dependence: A Systematic Review and Meta-Analysis.
Sangroula D, Motiwala F, Wagle B, Shah VC, Hagi K, Lippmann S. Sangroula D, et al. Subst Use Misuse. 2017 Aug 24;52(10):1292-1306. doi: 10.1080/10826084.2016.1276597. Epub 2017 Mar 28. Subst Use Misuse. 2017. PMID: 28350194
RESULTS: In total, 11 studies (participants = 896, duration = 6.7 1.9 weeks) comparing modafinil with placebo were systematically analyzed, which indicated that modafinil was not superior to placebo in improving the treatment retention rate (studies = 11, particip …
RESULTS: In total, 11 studies (participants = 896, duration = 6.7 1.9 weeks) comparing modafinil with placebo were systematically a …
Modafinil: a review of neurochemical actions and effects on cognition.
Minzenberg MJ, Carter CS. Minzenberg MJ, et al. Neuropsychopharmacology. 2008 Jun;33(7):1477-502. doi: 10.1038/sj.npp.1301534. Epub 2007 Aug 22. Neuropsychopharmacology. 2008. PMID: 17712350 Free article. Review.
Modafinil (2-[(Diphenylmethyl) sulfinyl] acetamide, Provigil) is an FDA-approved medication with wake-promoting properties. ...We additionally summarized the pharmacokinetic profile of modafinil and clinical efficacy in psychiatric patients. Modafinil exhibit …
Modafinil (2-[(Diphenylmethyl) sulfinyl] acetamide, Provigil) is an FDA-approved medication with wake-promoting properties. ...We add …
Effects of Modafinil (Provigil) on Memory and Learning in Experimental and Clinical Studies: From Molecular Mechanisms to Behaviour Molecular Mechanisms and Behavioural Effects.
Zamanian MY, Karimvandi MN, Nikbakhtzadeh M, Zahedi E, Bokov DO, Kujawska M, Heidari M, Rahmani MR. Zamanian MY, et al. Curr Mol Pharmacol. 2023;16(4):507-516. doi: 10.2174/1874467215666220901122824. Curr Mol Pharmacol. 2023. PMID: 36056861 Review.
Modafinil (MOD, 2-diphenyl-methyl-sulphinil-2-acetamide) is a stimulant-like medicine used to treat narcolepsy. ...
Modafinil (MOD, 2-diphenyl-methyl-sulphinil-2-acetamide) is a stimulant-like medicine used to treat narcolepsy. ...
2,372 results