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Page 1
The SLC16 gene family - structure, role and regulation in health and disease.
Halestrap AP. Halestrap AP. Mol Aspects Med. 2013 Apr-Jun;34(2-3):337-49. doi: 10.1016/j.mam.2012.05.003. Mol Aspects Med. 2013. PMID: 23506875 Review.
Four (SLC16A1, SLC16A3, SLC16A7, and SLC16A8) encode monocarboxylate transporters (MCT1, MCT4, MCT2, and MCT3, respectively) catalysing the proton-linked transport of monocarboxylates such as l-lactate, pyruvate and ketone bodies across the plasma m …
Four (SLC16A1, SLC16A3, SLC16A7, and SLC16A8) encode monocarboxylate transporters (MCT1, MCT4, MCT2, and MCT3, respectively) c …
Monocarboxylic acid transport.
Halestrap AP. Halestrap AP. Compr Physiol. 2013 Oct;3(4):1611-43. doi: 10.1002/cphy.c130008. Compr Physiol. 2013. PMID: 24265240 Review.
Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in metabolism and must be transported across both the plasma membrane and mitochondrial inner membrane. ...In the intestine and kidney, two Sodium-coupled MonoCarboxy …
Monocarboxylates such as lactate, pyruvate, and the ketone bodies play major roles in metabolism and must be transported acros …
CD147: an integral and potential molecule to abrogate hallmarks of cancer.
Nyalali AMK, Leonard AU, Xu Y, Li H, Zhou J, Zhang X, Rugambwa TK, Shi X, Li F. Nyalali AMK, et al. Front Oncol. 2023 Nov 7;13:1238051. doi: 10.3389/fonc.2023.1238051. eCollection 2023. Front Oncol. 2023. PMID: 38023152 Free PMC article. Review.
CD147 also known as EMMPRIN, basigin, and HAb18G, is a single-chain type I transmembrane protein shown to be overexpressed in aggressive human cancers of CNS, head and neck, breasts, lungs, gastrointestinal, genitourinary, skin, hematological, and musculoskeletal. ...These …
CD147 also known as EMMPRIN, basigin, and HAb18G, is a single-chain type I transmembrane protein shown to be overexpressed in aggress …
Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma.
Espíndola KMM, Ferreira RG, Narvaez LEM, Silva Rosario ACR, da Silva AHM, Silva AGB, Vieira APO, Monteiro MC. Espíndola KMM, et al. Front Oncol. 2019 Jun 21;9:541. doi: 10.3389/fonc.2019.00541. eCollection 2019. Front Oncol. 2019. PMID: 31293975 Free PMC article. Review.
This phenolic acid and its derivatives have antioxidant, anti-inflammatory and anticarcinogenic activity. ...Pharmacokinetic studies indicate that this compound is hydrolyzed by the microflora of colonies and metabolized mainly in the intestinal mucosa through phase …
This phenolic acid and its derivatives have antioxidant, anti-inflammatory and anticarcinogenic activity. ...Pharmacokinetic s …
Identification of Human TRIAC Transmembrane Transporters.
Becker PC, Güth-Steffens M, Lazarow K, Sonntag N, Braun D, Masfaka I, Renko K, Schomburg L, Köhrle J, von Kries JP, Schweizer U, Krause G, Protze J. Becker PC, et al. Thyroid. 2024 Jul;34(7):920-930. doi: 10.1089/thy.2023.0592. Epub 2024 Jul 1. Thyroid. 2024. PMID: 38801167
MDCK1 cells were stably transfected with cDNA encoding C-terminally myc-tagged versions of the identified TRIAC-preferring transporters. Several individual clones were selected after immunocytochemical characterization for biochemical characterization of their (125)I-TRIAC …
MDCK1 cells were stably transfected with cDNA encoding C-terminally myc-tagged versions of the identified TRIAC-preferring transporters …
Disorder of thyroid hormone transport into the tissues.
Groeneweg S, Visser WE, Visser TJ. Groeneweg S, et al. Best Pract Res Clin Endocrinol Metab. 2017 Mar;31(2):241-253. doi: 10.1016/j.beem.2017.05.001. Epub 2017 May 24. Best Pract Res Clin Endocrinol Metab. 2017. PMID: 28648511 Review.
Transport of thyroid hormone (TH) across the plasma membrane is essential for intracellular TH metabolism and action, and this is mediated by specific transporter proteins. During the last two decades several transporters capable of transport …
Transport of thyroid hormone (TH) across the plasma membrane is essential for intracellular TH metabolism and action, and this …
Molecular characteristic analysis of single-nucleotide polymorphisms in SLC16A9/hMCT9.
Yamaguchi A, Mukai Y, Sakuma T, Suganuma Y, Furugen A, Narumi K, Kobayashi M. Yamaguchi A, et al. Life Sci. 2023 Dec 1;334:122205. doi: 10.1016/j.lfs.2023.122205. Epub 2023 Oct 24. Life Sci. 2023. PMID: 37879602 Free article.
AIMS: Human monocarboxylate transporter 9 (hMCT9), encoded by SLC16A9, is a transporter that mediates creatine transport across the transmembrane. ...KEY FINDINGS: We assessed the transport activity of uric acid and creatine …
AIMS: Human monocarboxylate transporter 9 (hMCT9), encoded by SLC16A9, is a transporter that mediates creatine trans …
Intrinsic Asymmetry in Weak Acid Transmembrane Transporters.
Jaeger E, Buss S, Beitz E. Jaeger E, et al. Biomolecules. 2026 Jan 6;16(1):91. doi: 10.3390/biom16010091. Biomolecules. 2026. PMID: 41594631 Free PMC article. Review.
Transmembrane facilitation of substrates by channels and secondary active transporters results in a defined steady-state concentration ratio across the membrane. Evidence is accumulating that asymmetry in the structural build of the transporters …
Transmembrane facilitation of substrates by channels and secondary active transporters results in a defined steady-stat …
The monocarboxylate transporter family--Structure and functional characterization.
Halestrap AP. Halestrap AP. IUBMB Life. 2012 Jan;64(1):1-9. doi: 10.1002/iub.573. Epub 2011 Nov 30. IUBMB Life. 2012. PMID: 22131303 Free article. Review.
Monocarboxylate transporters (MCTs) catalyze the proton-linked transport of monocarboxylates such as L-lactate, pyruvate, and the ketone bodies across the plasma membrane. ...The family includes a high-affinity thyroid hormone transporter …
Monocarboxylate transporters (MCTs) catalyze the proton-linked transport of monocarboxylates such as L-lactate, …
Thyroid hormone transporters in the brain.
Braun D, Wirth EK, Schweizer U. Braun D, et al. Rev Neurosci. 2010;21(3):173-86. doi: 10.1515/revneuro.2010.21.3.173. Rev Neurosci. 2010. PMID: 20879691 Review.
Mutations in a thyroid hormone transmembrane transport protein, monocarboxylate transporter 8 (MCT8), underlie one of the first described X-linked mental retardation syndromes, the Allan-Herndon-Dudley syndrome. ...Thyroid hormones are translocated acr …
Mutations in a thyroid hormone transmembrane transport protein, monocarboxylate transporter 8 (MCT8), underlie o …
89 results