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2000 15
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481 results

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Page 1
A Test of Dietary Monosodium Glutamate Developmental Neurotoxicity in Rats: A Reappraisal.
Vorhees CV. Vorhees CV. Ann Nutr Metab. 2018;73 Suppl 5:36-42. doi: 10.1159/000494781. Epub 2018 Dec 3. Ann Nutr Metab. 2018. PMID: 30508817 Free article. Review.
In 1979, we tested dietary monosodium glutamate (MSG) for developmental neurotoxicity in rats. The study was recently cited for establishing a No Observable Adverse Effect Level (NOAEL) for MSG as a food additive resulting in a change in the acceptable daily …
In 1979, we tested dietary monosodium glutamate (MSG) for developmental neurotoxicity in rats. The study was recently c …
A review of the alleged health hazards of monosodium glutamate.
Zanfirescu A, Ungurianu A, Tsatsakis AM, Nițulescu GM, Kouretas D, Veskoukis A, Tsoukalas D, Engin AB, Aschner M, Margină D. Zanfirescu A, et al. Compr Rev Food Sci Food Saf. 2019 Jul;18(4):1111-1134. doi: 10.1111/1541-4337.12448. Epub 2019 May 8. Compr Rev Food Sci Food Saf. 2019. PMID: 31920467 Free PMC article.
Monosodium glutamate (MSG) is an umami substance widely used as flavor enhancer. Although it is generally recognized as being safe by food safety regulatory agencies, several studies have questioned its long-term safety. ...Preclinical studies have associated MSG ad …
Monosodium glutamate (MSG) is an umami substance widely used as flavor enhancer. Although it is generally recognized as being …
Excitotoxicity and stroke: identifying novel targets for neuroprotection.
Lai TW, Zhang S, Wang YT. Lai TW, et al. Prog Neurobiol. 2014 Apr;115:157-88. doi: 10.1016/j.pneurobio.2013.11.006. Epub 2013 Dec 17. Prog Neurobiol. 2014. PMID: 24361499 Free article. Review.
Excitotoxicity, the specific type of neurotoxicity mediated by glutamate, may be the missing link between ischemia and neuronal death, and intervening the mechanistic steps that lead to excitotoxicity can prevent stroke damage. Interest in excitotoxicity began fifty …
Excitotoxicity, the specific type of neurotoxicity mediated by glutamate, may be the missing link between ischemia and neurona …
Arbutin attenuates monosodium L-glutamate induced neurotoxicity and cognitive dysfunction in rats.
Kumar M, Kumar A, Sindhu RK, Kushwah AS. Kumar M, et al. Neurochem Int. 2021 Dec;151:105217. doi: 10.1016/j.neuint.2021.105217. Epub 2021 Oct 25. Neurochem Int. 2021. PMID: 34710534
Excitotoxicity, oxidative stress, and neuro-inflammation underlie the pathogenesis of neurodegenerative brain disorders. Although L-glutamate is the prime excitatory neurotransmitter involved in diverse brain functions, however, overabundance at synapse can activate cell d …
Excitotoxicity, oxidative stress, and neuro-inflammation underlie the pathogenesis of neurodegenerative brain disorders. Although L-gluta …
Protective effect of Danshensu against neurotoxicity induced by monosodium glutamate in adult mice and their offspring.
Liang Q, Li D, Li J, Li Y, Zou Y, Zhang Y. Liang Q, et al. Heliyon. 2024 Feb 1;10(3):e25546. doi: 10.1016/j.heliyon.2024.e25546. eCollection 2024 Feb 15. Heliyon. 2024. PMID: 38356496 Free PMC article.
Excessive neuronal excitation by glutamate is a well-established cause of neurotoxicity, leading to severe impairment of brain function. ...In this study, we investigated the neuroprotective effects of Danshensu (DSS) against monosodium glutamate (MSG) …
Excessive neuronal excitation by glutamate is a well-established cause of neurotoxicity, leading to severe impairment of brain …
Assessment of the neurotoxicity of monosodium glutamate on neural stem cells and hippocampal neurogenesis in a rodent model.
Kim I, Yang S, Kim CY, Kim S, Jung YS, Chung HY, Lee J. Kim I, et al. Food Chem Toxicol. 2025 Jan;195:115136. doi: 10.1016/j.fct.2024.115136. Epub 2024 Nov 23. Food Chem Toxicol. 2025. PMID: 39581299
Monosodium glutamate (MSG) is a widely used flavor enhancer in processed foods and valued for its ability to enhance the savory taste known as umami. ...Furthermore, in vivo studies on 4-week-old male C57BL/6 mice orally administered MSG and sodium chloride ( …
Monosodium glutamate (MSG) is a widely used flavor enhancer in processed foods and valued for its ability to enhance the savor …
Natural products as safeguards against monosodium glutamate-induced toxicity.
Hajihasani MM, Soheili V, Zirak MR, Sahebkar A, Shakeri A. Hajihasani MM, et al. Iran J Basic Med Sci. 2020 Apr;23(4):416-430. doi: 10.22038/IJBMS.2020.43060.10123. Iran J Basic Med Sci. 2020. PMID: 32489556 Free PMC article. Review.
Monosodium glutamate is a sodium salt of a nonessential amino acid, L-glutamic acid, which is widely used in food industry. ...However, ingestion of foodstuffs rich in monosodium glutamate can result in the outbreak of several health disorders s …
Monosodium glutamate is a sodium salt of a nonessential amino acid, L-glutamic acid, which is widely used in food indus …
Monosodium glutamate neurotoxicity, hyperosmolarity, and blood-brain barrier dysfunction.
McCall A, Glaeser BS, Millington W, Wurtman RJ. McCall A, et al. Neurobehav Toxicol. 1979 Winter;1(4):279-83. Neurobehav Toxicol. 1979. PMID: 121936
Rats received 3H-mannitol, which marks the intactness of the blood-brain barrier, and 14C-glutamate or 14C-aspartate by intracardiac injection after oral gavage with water, monosodium glutamate, monosodium aspartate, or sodium chloride (doses eq …
Rats received 3H-mannitol, which marks the intactness of the blood-brain barrier, and 14C-glutamate or 14C-aspartate by intracardiac …
Glutamate receptors, neurotoxicity and neurodegeneration.
Lau A, Tymianski M. Lau A, et al. Pflugers Arch. 2010 Jul;460(2):525-42. doi: 10.1007/s00424-010-0809-1. Epub 2010 Mar 14. Pflugers Arch. 2010. PMID: 20229265 Review.
Glutamate excitotoxicity is a hypothesis that states excessive glutamate causes neuronal dysfunction and degeneration. As glutamate is a major excitatory neurotransmitter in the central nervous system (CNS), the implications of glutamate excitotoxicity …
Glutamate excitotoxicity is a hypothesis that states excessive glutamate causes neuronal dysfunction and degeneration. As g …
Effect of parental perinatal exposure to L-glutamate monosodium salt monohydrate on developmental neurotoxicity in rat offspring.
Huang Z, Xiao X, Zhang X, Jiang H, Zhao X, Wei Q, Yang X, Sui H, Ou T, Yang D, Zhang W, Jia X, Song Y, Yong L. Huang Z, et al. Toxicol Appl Pharmacol. 2025 Sep;502:117450. doi: 10.1016/j.taap.2025.117450. Epub 2025 Jun 24. Toxicol Appl Pharmacol. 2025. PMID: 40570974
This study aimed to provide preliminary information about the potential adverse effects of L-Glutamate Monosodium Salt Monohydrate on maternal health and offspring development, particularly about developmental neurotoxicity and abnormal behavior in offspring …
This study aimed to provide preliminary information about the potential adverse effects of L-Glutamate Monosodium Salt Monohyd …
481 results