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2011 1
2017 3
2018 1
2019 1
2021 0
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International approaches to advancing biospecimen science.
Moore HM, Compton CC, Alper J, Vaught JB. Moore HM, et al. Cancer Epidemiol Biomarkers Prev. 2011 May;20(5):729-32. doi: 10.1158/1055-9965.EPI-11-0021. Epub 2011 Mar 23. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21430299 Free PMC article.
Biospecimen quality is affected by a number of preanalytical factors that may or may not be obvious to the investigator. ...A variety of efforts are under way around the world to establish research programs, evidence-based biospecimen protocols, and standards to imp
Biospecimen quality is affected by a number of preanalytical factors that may or may not be obvious to the investigator. ...A variety
Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma.
Connor AA, Denroche RE, Jang GH, Timms L, Kalimuthu SN, Selander I, McPherson T, Wilson GW, Chan-Seng-Yue MA, Borozan I, Ferretti V, Grant RC, Lungu IM, Costello E, Greenhalf W, Palmer D, Ghaneh P, Neoptolemos JP, Buchler M, Petersen G, Thayer S, Hollingsworth MA, Sherker A, Durocher D, Dhani N, Hedley D, Serra S, Pollett A, Roehrl MHA, Bavi P, Bartlett JMS, Cleary S, Wilson JM, Alexandrov LB, Moore M, Wouters BG, McPherson JD, Notta F, Stein LD, Gallinger S. Connor AA, et al. JAMA Oncol. 2017 Jun 1;3(6):774-783. doi: 10.1001/jamaoncol.2016.3916. JAMA Oncol. 2017. PMID: 27768182 Free PMC article.
Advances in next-generation sequencing provide a route to therapeutic approaches, and integrating DNA and RNA analysis with clinicopathologic data may be a crucial step toward personalized treatment strategies for this disease. ...The replication cohort comprised 95 primar …
Advances in next-generation sequencing provide a route to therapeutic approaches, and integrating DNA and RNA analysis with clinicopa …
Understanding preanalytical variables and their effects on clinical biomarkers of oncology and immunotherapy.
Agrawal L, Engel KB, Greytak SR, Moore HM. Agrawal L, et al. Semin Cancer Biol. 2018 Oct;52(Pt 2):26-38. doi: 10.1016/j.semcancer.2017.12.008. Epub 2017 Dec 16. Semin Cancer Biol. 2018. PMID: 29258857 Free PMC article. Review.
Identifying a suitable course of immunotherapy treatment for a given patient as well as monitoring treatment response is heavily reliant on biomarkers detected and quantified in blood and tissue biospecimens. Suboptimal or variable biospecimen collection, processing …
Identifying a suitable course of immunotherapy treatment for a given patient as well as monitoring treatment response is heavily reliant on …
Metabolomics Analytics Workflow for Epidemiological Research: Perspectives from the Consortium of Metabolomics Studies (COMETS).
Playdon MC, Joshi AD, Tabung FK, Cheng S, Henglin M, Kim A, Lin T, van Roekel EH, Huang J, Krumsiek J, Wang Y, Mathé E, Temprosa M, Moore S, Chawes B, Eliassen AH, Gsur A, Gunter MJ, Harada S, Langenberg C, Oresic M, Perng W, Seow WJ, Zeleznik OA. Playdon MC, et al. Metabolites. 2019 Jul 17;9(7):145. doi: 10.3390/metabo9070145. Metabolites. 2019. PMID: 31319517 Free PMC article.
The application of metabolomics technology to epidemiological studies is emerging as a new approach to elucidate disease etiology and for biomarker discovery. ...The results indicated a variety of applied analytical strategies, from biospecimen and data pre-processi …
The application of metabolomics technology to epidemiological studies is emerging as a new approach to elucidate disease etiology and …
Societal challenges of precision medicine: Bringing order to chaos.
Salgado R, Moore H, Martens JWM, Lively T, Malik S, McDermott U, Michiels S, Moscow JA, Tejpar S, McKee T, Lacombe D; IBCD-Faculty. Salgado R, et al. Eur J Cancer. 2017 Oct;84:325-334. doi: 10.1016/j.ejca.2017.07.028. Epub 2017 Sep 4. Eur J Cancer. 2017. PMID: 28865260 Free PMC article.
The increasing number of drugs targeting specific proteins implicated in tumourigenesis and the commercial promotion of relatively affordable genome-wide analyses has led to an increasing expectation among patients with cancer that they can now receive effective personalised trea …
The increasing number of drugs targeting specific proteins implicated in tumourigenesis and the commercial promotion of relatively affordabl …