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Year Number of Results
2006 1
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2011 2
2012 2
2013 4
2014 5
2015 7
2016 9
2017 7
2018 9
2019 10
2020 12
2021 10
2022 10
2023 6
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116 results

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Page 1
Ablation of FAS confers allogeneic CD3- CAR T cells with resistance to rejection by T cells and natural killer cells.
Menegatti S, Lopez-Cobo S, Sutra Del Galy A, Fuentealba J, Silva L, Perrin L, Heurtebise-Chrétien S, Pottez-Jouatte V, Darbois A, Burgdorf N, Privat AL, Simon A, Laprie-Sentenac M, Saitakis M, Wick B, Webber BR, Moriarity BS, Lantz O, Amigorena S, Menger L. Menegatti S, et al. Among authors: moriarity bs. Nat Biomed Eng. 2024 Dec;8(12):1651-1664. doi: 10.1038/s41551-024-01282-8. Epub 2024 Nov 18. Nat Biomed Eng. 2024. PMID: 39558141
Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial.
Lou E, Choudhry MS, Starr TK, Folsom TD, Bell J, Rathmann B, DeFeo AP, Kim J, Slipek N, Jin Z, Sumstad D, Klebanoff CA, Ladner K, Sarkari A, McIvor RS, Murray TA, Miller JS, Rao M, Jensen E, Ankeny J, Khalifa MA, Chauhan A, Spilseth B, Dixit A, Provenzano PP, Pan W, Weber D, Byrne-Steele M, Henley T, McKenna DH, Johnson MJ, Webber BR, Moriarity BS. Lou E, et al. Among authors: moriarity bs. Lancet Oncol. 2025 May;26(5):559-570. doi: 10.1016/S1470-2045(25)00083-X. Epub 2025 Apr 29. Lancet Oncol. 2025. PMID: 40315882 Clinical Trial.
Primary B cell engineering for therapeutic research.
Kleinboehl E, Laoharawee K, Moriarity BS. Kleinboehl E, et al. Among authors: moriarity bs. Trends Mol Med. 2022 Jun;28(6):528-529. doi: 10.1016/j.molmed.2022.03.007. Epub 2022 Apr 13. Trends Mol Med. 2022. PMID: 35430120 Free PMC article. No abstract available.
A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance.
Fan JJ, Erickson AW, Carrillo-Garcia J, Wang X, Skowron P, Wang X, Chen X, Shan G, Dou W, Bahrampour S, Xiong Y, Dong W, Abeysundara N, Francisco MA, Pusong RJ, Wang W, Li M, Ying E, Suárez RA, Farooq H, Holgado BL, Wu X, Daniels C, Dupuy AJ, Cadiñanos J, Bradley A, Bagchi A, Moriarity BS, Largaespada DA, Morrissy AS, Ramaswamy V, Mack SC, Garzia L, Dirks PB, Li X, Wanggou S, Egan S, Sun Y, Taylor MD, Huang X. Fan JJ, et al. Among authors: moriarity bs. Dev Cell. 2025 Jun 9;60(11):1532-1549.e7. doi: 10.1016/j.devcel.2025.01.001. Epub 2025 Jan 24. Dev Cell. 2025. PMID: 39862856
Functional genomics for improving adoptive T-cell transfer therapies.
Skeate JG, Lee CJ, Stewart C, Fischbach MJ, Kar B, Tsai AK, Kenderian SS, Stromnes IM, Largaespada DA, Moriarity BS, Rogers LM. Skeate JG, et al. Among authors: moriarity bs. J Immunother Cancer. 2025 Dec 9;13(12):e013286. doi: 10.1136/jitc-2025-013286. J Immunother Cancer. 2025. PMID: 41365534 Free PMC article. Review.
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Palmer DC, Webber BR, Patel Y, Johnson MJ, Kariya CM, Lahr WS, Parkhurst MR, Gartner JJ, Prickett TD, Lowery FJ, Kishton RJ, Gurusamy D, Franco Z, Vodnala SK, Diers MD, Wolf NK, Slipek NJ, McKenna DH, Sumstad D, Viney L, Henley T, Bürckstümmer T, Baker O, Hu Y, Yan C, Meerzaman D, Padhan K, Lo W, Malekzadeh P, Jia L, Deniger DC, Patel SJ, Robbins PF, McIvor RS, Choudhry M, Rosenberg SA, Moriarity BS, Restifo NP. Palmer DC, et al. Among authors: moriarity bs. Med. 2022 Oct 14;3(10):682-704.e8. doi: 10.1016/j.medj.2022.07.008. Epub 2022 Aug 24. Med. 2022. PMID: 36007524 Free PMC article.
Genome Engineering of Primary Human B Cells Using CRISPR/Cas9.
Laoharawee K, Johnson MJ, Lahr WS, Peterson JJ, Webber BR, Moriarity BS. Laoharawee K, et al. Among authors: moriarity bs. J Vis Exp. 2020 Nov 3;(165):10.3791/61855. doi: 10.3791/61855. J Vis Exp. 2020. PMID: 33226023 Free PMC article.
116 results