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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
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1975 7
1976 4
1977 8
1978 6
1979 8
1980 10
1981 7
1982 9
1983 7
1984 4
1985 7
1986 10
1987 12
1988 11
1989 26
1990 15
1991 15
1992 16
1993 15
1994 18
1995 22
1996 25
1997 44
1998 68
1999 84
2000 154
2001 240
2002 301
2003 389
2004 508
2005 663
2006 710
2007 828
2008 1042
2009 1129
2010 1403
2011 1517
2012 1761
2013 2142
2014 2504
2015 2914
2016 3128
2017 3131
2018 3172
2019 3157
2020 3583
2021 3882
2022 3753
2023 3416
2024 3508
2025 3885
2026 628

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31,129 results

Results by year

Filters applied: Abstract, in the last 10 years. Clear all
Page 1
MSC exosome works through a protein-based mechanism of action.
Toh WS, Lai RC, Zhang B, Lim SK. Toh WS, et al. Biochem Soc Trans. 2018 Aug 20;46(4):843-853. doi: 10.1042/BST20180079. Epub 2018 Jul 9. Biochem Soc Trans. 2018. PMID: 29986939 Free PMC article. Review.
Mesenchymal stem cell (MSC) exosome specifically defines the 50-200 nm vesicles that are secreted into the extracellular space when multivesicular bodies in the MSC fuse with the plasma membrane. ...They also carry a rich diverse RNA cargo. MSC exosomes are i …
Mesenchymal stem cell (MSC) exosome specifically defines the 50-200 nm vesicles that are secreted into the extracellular space when m …
Concise Review: MSC-Derived Exosomes for Cell-Free Therapy.
Phinney DG, Pittenger MF. Phinney DG, et al. Stem Cells. 2017 Apr;35(4):851-858. doi: 10.1002/stem.2575. Epub 2017 Mar 10. Stem Cells. 2017. PMID: 28294454 Review.
However, the MSC exosome's contents are not static, but rather a product of the MSC tissue origin, its activities and the immediate intercellular neighbors of the MSCs. ...Therefore, careful attention to detail in producing MSC exosomes may provide a new ther …
However, the MSC exosome's contents are not static, but rather a product of the MSC tissue origin, its activities and the imme …
MSC-Exos: Important active factor of bone regeneration.
Ren S, Lin Y, Liu W, Yang L, Zhao M. Ren S, et al. Front Bioeng Biotechnol. 2023 Feb 6;11:1136453. doi: 10.3389/fbioe.2023.1136453. eCollection 2023. Front Bioeng Biotechnol. 2023. PMID: 36814713 Free PMC article. Review.
Numerous studies have shown that the bone regenerative effects of MSC can be achieved through exosome-delivered messages. Although its osteogenic mechanism is still unclear, it is clear that MSC-Exos can directly or indirectly support the action of bone regeneration …
Numerous studies have shown that the bone regenerative effects of MSC can be achieved through exosome-delivered messages. Although it …
Engineering the MSC Secretome: A Hydrogel Focused Approach.
Wechsler ME, Rao VV, Borelli AN, Anseth KS. Wechsler ME, et al. Adv Healthc Mater. 2021 Apr;10(7):e2001948. doi: 10.1002/adhm.202001948. Epub 2021 Feb 17. Adv Healthc Mater. 2021. PMID: 33594836 Free PMC article. Review.
The therapeutic benefits of exogenously delivered mesenchymal stromal/stem cells (MSCs) have been largely attributed to their secretory properties. However, clinical translation of MSC-based therapies is hindered due to loss of MSC regenerative properties during lar …
The therapeutic benefits of exogenously delivered mesenchymal stromal/stem cells (MSCs) have been largely attributed to their secretory prop …
Bioengineered MSC-derived exosomes in skin wound repair and regeneration.
Zhao H, Li Z, Wang Y, Zhou K, Li H, Bi S, Wang Y, Wu W, Huang Y, Peng B, Tang J, Pan B, Wang B, Chen Z, Zhang Z. Zhao H, et al. Front Cell Dev Biol. 2023 Feb 27;11:1029671. doi: 10.3389/fcell.2023.1029671. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36923255 Free PMC article. Review.
The beneficial role of MSC-exosomes in wound healing is been widely accepted; however, the potential of bioengineering-modified MSC-exosomes remains unclear. In this review, we attempt to summarize the therapeutic applications of modified MSC-exosomes in woun …
The beneficial role of MSC-exosomes in wound healing is been widely accepted; however, the potential of bioengineering-modified MS …
[MSC Senescence-related Signaling Pathway - Review].
Yang YZ, Zhang XY, Li J. Yang YZ, et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2018 Feb;26(1):307-310. doi: 10.7534/j.issn.1009-2137.2018.01.055. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2018. PMID: 29397864 Review. Chinese.
Also, MSC senescence may promote the individual senility, hypofunction of tissue and organ, and tumorigenesis. Thus, in order to better understand the senescent mechanism and delay the senescence, even reverse MSC senescence, the roles of signaling pathway, such as …
Also, MSC senescence may promote the individual senility, hypofunction of tissue and organ, and tumorigenesis. Thus, in order to bett …
Mammalian MSC from selected species: Features and applications.
Uder C, Brückner S, Winkler S, Tautenhahn HM, Christ B. Uder C, et al. Cytometry A. 2018 Jan;93(1):32-49. doi: 10.1002/cyto.a.23239. Epub 2017 Sep 14. Cytometry A. 2018. PMID: 28906582 Free article. Review.
In addition, multiple differentiation potential into at least the osteogenic, adipogenic, and chondrogenic lineage is a main criterion for MSC definition. Human MSC and MSC of a variety of mammals isolated from different tissues meet these criteria. ...Yet, t …
In addition, multiple differentiation potential into at least the osteogenic, adipogenic, and chondrogenic lineage is a main criterion for …
MSC-Derived Extracellular Vesicles: Roles and Molecular Mechanisms for Tissue Repair.
Wu T, Liu Y, Wang S, Shi C. Wu T, et al. Int J Nanomedicine. 2025 Jun 21;20:7953-7974. doi: 10.2147/IJN.S525394. eCollection 2025. Int J Nanomedicine. 2025. PMID: 40568355 Free PMC article. Review.
Therefore, MSC-EVs are emerging as a cell-free alternative therapy for MSC-based cell therapy. Here, we reviewed the characteristics of different subtype of MSC-EVs, the functional molecules in MSC-EVs for tissue repair, the potential applications of …
Therefore, MSC-EVs are emerging as a cell-free alternative therapy for MSC-based cell therapy. Here, we reviewed the character …
Novel insights into MSC-EVs therapy for immune diseases.
Lai P, Weng J, Guo L, Chen X, Du X. Lai P, et al. Biomark Res. 2019 Mar 18;7:6. doi: 10.1186/s40364-019-0156-0. eCollection 2019. Biomark Res. 2019. PMID: 30923617 Free PMC article. Review.
Since MSC-EVs exhibit most of the properties of MSC and take advantage of their cellular immunomodulatory fuction, MSC-EVs appear to a promising none-cell therapy in various human diseases. In this review, we summarize the pivotal roles of MSC-EVs as a …
Since MSC-EVs exhibit most of the properties of MSC and take advantage of their cellular immunomodulatory fuction, MSC- …
Specificity of 3D MSC Spheroids Microenvironment: Impact on MSC Behavior and Properties.
Jauković A, Abadjieva D, Trivanović D, Stoyanova E, Kostadinova M, Pashova S, Kestendjieva S, Kukolj T, Jeseta M, Kistanova E, Mourdjeva M. Jauković A, et al. Stem Cell Rev Rep. 2020 Oct;16(5):853-875. doi: 10.1007/s12015-020-10006-9. Stem Cell Rev Rep. 2020. PMID: 32681232 Review.
The opportunity to resemble in vivo characteristics of cells native niche has been provided by implementation of 3D culturing models such as MSC spheroid formation assesed through cells self-assembling. In this review, we address the current literature on physical and bioc …
The opportunity to resemble in vivo characteristics of cells native niche has been provided by implementation of 3D culturing models such as …
31,129 results
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