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Page 1
Mucuna pruriens, a Possible Treatment for Depressive Disorders.
Mata-Bermudez A, Diaz-Ruiz A, Silva-García LR, Gines-Francisco EM, Noriega-Navarro R, Rios C, Romero-Sánchez HA, Arroyo D, Landa A, Navarro L. Mata-Bermudez A, et al. Neurol Int. 2024 Nov 16;16(6):1509-1527. doi: 10.3390/neurolint16060112. Neurol Int. 2024. PMID: 39585071 Free PMC article. Review.
Treatments with conventional antidepressants have several limitations in terms of effectiveness, side effects, and high costs. Therefore, medicinal plants such as Mucuna pruriens are potent candidates for treating depressive disorders. This review shows a compendium …
Treatments with conventional antidepressants have several limitations in terms of effectiveness, side effects, and high costs. Therefore, me …
Dopamine mediated antidepressant effect of Mucuna pruriens seeds in various experimental models of depression.
Rana DG, Galani VJ. Rana DG, et al. Ayu. 2014 Jan;35(1):90-7. doi: 10.4103/0974-8520.141949. Ayu. 2014. PMID: 25364207 Free PMC article.
Multiple lines of investigation have also explored the role of dopaminergic systems in mental depression. Seed of Mucuna pruriens Linn. (DC) (Leguminoseae) is well-known with dopaminergic action and has several therapeutic applications in folk medicine in curing or …
Multiple lines of investigation have also explored the role of dopaminergic systems in mental depression. Seed of Mucuna pruriens …
Sexual stimulatory effects of Mucuna pruriens in rodents: An experiment following Ayurvedic perspective.
Dhanasekaran M, Tharakan B, Jeyabalan JB, Pathak S, Liu K, Nadar R, Moore T. Dhanasekaran M, et al. J Ayurveda Integr Med. 2025 May-Jun;16(3):101130. doi: 10.1016/j.jaim.2025.101130. Epub 2025 Jun 9. J Ayurveda Integr Med. 2025. PMID: 40494136 Free PMC article.
Erectile dysfunction is frequently related to low dopamine levels and hyperglycemia, both of which can be alleviated by Mucuna pruriens, a natural source of levodopa and other bioactive compounds. ...METHODS: Standardized Mucuna pruriens extract …
Erectile dysfunction is frequently related to low dopamine levels and hyperglycemia, both of which can be alleviated by Mucuna …
Neuroprotective effects of the antiparkinson drug Mucuna pruriens.
Manyam BV, Dhanasekaran M, Hare TA. Manyam BV, et al. Phytother Res. 2004 Sep;18(9):706-12. doi: 10.1002/ptr.1514. Phytother Res. 2004. PMID: 15478206
Unlike synthetic levodopa treatment, Mucuna pruriens cotyledon powder treatment significantly restored the endogenous levodopa, dopamine, norepinephrine and serotonin content in the substantia nigra. Nicotine adenine dinucleotide (NADH) and coenzyme Q-10, tha …
Unlike synthetic levodopa treatment, Mucuna pruriens cotyledon powder treatment significantly restored the endogenous levodopa …
Recovery of motor function is associated with rescue of glutamate biomarkers in the striatum and motor cortex following treatment with Mucuna pruriens in a murine model of Parkinsons disease.
Denne T, Winfrey LC, Moore C, Whitner C, D'Silva T, Soumyanath A, Shinto L, Hiller A, Meshul CK. Denne T, et al. Mol Cell Neurosci. 2023 Sep;126:103883. doi: 10.1016/j.mcn.2023.103883. Epub 2023 Jul 30. Mol Cell Neurosci. 2023. PMID: 37527694
There is growing interest in the use of natural products for the treatment of Parkinson's disease (PD). Mucuna pruriens has been used in the treatment of humans with PD. The goal of this study was to determine if daily oral treatment with an extract of Mucuna …
There is growing interest in the use of natural products for the treatment of Parkinson's disease (PD). Mucuna pruriens has be …
Protective effect of Mucuna pruriens (L.) DC. var. pruriens seed extract on apoptotic germ cells in ethanolic male rats.
Samrid R, Taoto C, Wu A, Sawatpanich T, Phunchago N, Uabundit N, Iamsaard S. Samrid R, et al. Braz J Biol. 2023 Jul 10;83:e272629. doi: 10.1590/1519-6984.272629. eCollection 2023. Braz J Biol. 2023. PMID: 37436191 Free article.
Thai Mucuna pruriens (L.) DC. var pruriens (T-MP) seed containing levodopa (L-DOPA) and antioxidant capacity has been shown to improve sexual behavior and male reproductive parameters in rats treated with ethanol (Eth). ...This study aimed to investigate the …
Thai Mucuna pruriens (L.) DC. var pruriens (T-MP) seed containing levodopa (L-DOPA) and antioxidant capacity has been s …
Effect of antiparkinson drug HP-200 (Mucuna pruriens) on the central monoaminergic neurotransmitters.
Manyam BV, Dhanasekaran M, Hare TA. Manyam BV, et al. Phytother Res. 2004 Feb;18(2):97-101. doi: 10.1002/ptr.1407. Phytother Res. 2004. PMID: 15022157
HP-200, which contains Mucuna pruriens endocarp, has been shown to be effective in the treatment of Parkinson's disease. Mucuna pruriens endocarp has also been shown to be more effective compared to synthetic levodopa in an animal model of Parkinson's …
HP-200, which contains Mucuna pruriens endocarp, has been shown to be effective in the treatment of Parkinson's disease. Mu …
Chromosomal-level genome of velvet bean (Mucuna pruriens) provides resources for L-DOPA synthetic research and development.
Hao S, Ge Q, Shao Y, Tang B, Fan G, Qiu C, Wu X, Li L, Liu X, Shi C, Lee SM. Hao S, et al. DNA Res. 2022 Aug 23;29(5):dsac031. doi: 10.1093/dnares/dsac031. DNA Res. 2022. PMID: 35980175 Free PMC article.
Mucuna pruriens, commonly called velvet bean, is the main natural source of levodopa (L-DOPA), which has been marketed as a psychoactive drug for the clinical management of Parkinson's disease and dopamine-responsive dystonia. ...
Mucuna pruriens, commonly called velvet bean, is the main natural source of levodopa (L-DOPA), which has been marketed as a ps …
A Comprehensive Review of the Therapeutic Potential of Mucuna Pruriens.
Bashev Z, Karcheva-Bahchevanska D, Ardasheva R, Ivanova S. Bashev Z, et al. Molecules. 2026 Mar 5;31(5):868. doi: 10.3390/molecules31050868. Molecules. 2026. PMID: 41828855 Free PMC article. Review.
Mucuna pruriens (L.) DC. (Fabaceae), commonly known as velvet bean, is an annual tropical legume widely distributed in India, Africa, and the Americas. ...Most studies concentrated on the chemical characterization of the seeds, whereas the leaves, roots, and pods ha …
Mucuna pruriens (L.) DC. (Fabaceae), commonly known as velvet bean, is an annual tropical legume widely distributed in India, …
42 results