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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 1
1996 1
2002 2
2003 2
2004 4
2005 1
2006 3
2007 2
2008 2
2009 5
2010 4
2011 10
2012 11
2013 13
2014 13
2015 16
2016 11
2017 17
2018 7
2019 17
2020 18
2021 12
2022 8
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160 results
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Page 1
Helminth therapy and multiple sclerosis.
Fleming JO. Fleming JO. Int J Parasitol. 2013 Mar;43(3-4):259-74. doi: 10.1016/j.ijpara.2012.10.025. Epub 2013 Jan 5. Int J Parasitol. 2013. PMID: 23298637 Review.
Multiple sclerosis is a common and frequently disabling neurological disease of young adults. ...According to the hygiene (microbial deprivation) hypothesis, evolutionarily abnormal high levels of sanitation in the environment of the developed world may contribute t
Multiple sclerosis is a common and frequently disabling neurological disease of young adults. ...According to the hygiene (mic
Perspectives of People with Multiple Sclerosis About Helminth Immunotherapy.
Donkers SJ, Kirkland MC, Charabati M, Osborne LC. Donkers SJ, et al. Int J MS Care. 2020 Jan-Feb;22(1):43-51. doi: 10.7224/1537-2073.2019-044. Int J MS Care. 2020. PMID: 32123528 Free PMC article.
BACKGROUND: Due to the chronic and incurable nature of the autoimmune disease multiple sclerosis (MS), some people with MS will seek out alternative therapeutic approaches. ...RESULTS: Four main themes were generated: experience of living with MS, influential factor …
BACKGROUND: Due to the chronic and incurable nature of the autoimmune disease multiple sclerosis (MS), some people with MS wil …
A critical analysis of helminth immunotherapy in multiple sclerosis.
Charabati M, Donkers SJ, Kirkland MC, Osborne LC. Charabati M, et al. Mult Scler. 2020 Oct;26(12):1448-1458. doi: 10.1177/1352458519899040. Epub 2020 Jan 23. Mult Scler. 2020. PMID: 31971074
This concept and the geographic discrepancy between global burdens of chronic inflammatory diseases and helminth infection have sparked interest in the potential of using helminthic worms as a therapeutic intervention to limit the progression of autoimmune diseases …
This concept and the geographic discrepancy between global burdens of chronic inflammatory diseases and helminth infection have spark …
Does helminth activation of toll-like receptors modulate immune response in multiple sclerosis patients?
Correale J, Farez MF. Correale J, et al. Front Cell Infect Microbiol. 2012 Aug 24;2:112. doi: 10.3389/fcimb.2012.00112. eCollection 2012. Front Cell Infect Microbiol. 2012. PMID: 22937527 Free PMC article. Review.
Multiple sclerosis (MS) is an inflammatory autoimmune demyelinating disease affecting the Central Nervous System (CNS), in which Th1 and Th17 cells appear to recognize and react against certain myelin sheath components. ...In addition, helminth antigens signi
Multiple sclerosis (MS) is an inflammatory autoimmune demyelinating disease affecting the Central Nervous System (CNS), in whi
Modeling neurodegeneration in Caenorhabditiselegans.
Caldwell KA, Willicott CW, Caldwell GA. Caldwell KA, et al. Dis Model Mech. 2020 Oct 26;13(10):dmm046110. doi: 10.1242/dmm.046110. Dis Model Mech. 2020. PMID: 33106318 Free PMC article. Review.
The nematode Caenorhabditis elegans has served as the experimental subject for multiple transformative discoveries that have redefined our understanding of biology for 60 years. More recently, the considerable attributes of C. elegans have been applied to neurodegenerative …
The nematode Caenorhabditis elegans has served as the experimental subject for multiple transformative discoveries that have redefine …
Interleukin-35 is a critical regulator of immunity during helminth infections associated with multiple sclerosis.
Correale J, Marrodan M, Carnero Contentti E. Correale J, et al. Immunology. 2021 Nov;164(3):569-586. doi: 10.1111/imm.13389. Epub 2021 Jul 14. Immunology. 2021. PMID: 34197631 Free PMC article.
Multiple sclerosis (MS) is currently thought to arise by interactions between genetic susceptibility and environmental factors. ...These data highlight the important immunoregulatory effects of IL-35 on both Breg and Treg cells, observed in helminth-infected
Multiple sclerosis (MS) is currently thought to arise by interactions between genetic susceptibility and environmental factors
Immune-Regulatory Mechanisms of Classical and Experimental Multiple Sclerosis Drugs: A Special Focus on Helminth-Derived Treatments.
Peón AN, Terrazas LI. Peón AN, et al. Curr Med Chem. 2016;23(11):1152-70. doi: 10.2174/0929867323666160311114110. Curr Med Chem. 2016. PMID: 26947777 Review.
Multiple sclerosis (MS) is the most prevalent autoimmune disease affecting the central nervous system (CNS). ...Additionally, we will compare the mechanisms of action of both the MS drugs and the helminth-derived treatments to discuss the potential importance
Multiple sclerosis (MS) is the most prevalent autoimmune disease affecting the central nervous system (CNS). ...Additionally,
Helminth/Parasite treatment of multiple sclerosis.
Correale J. Correale J. Curr Treat Options Neurol. 2014 Jun;16(6):296. doi: 10.1007/s11940-014-0296-3. Curr Treat Options Neurol. 2014. PMID: 24744099
Epidemiological studies suggest that autoimmune diseases, such as multiple sclerosis (MS), are less frequent in individuals who are helminth carriers. This observation has been tested in murine models of colitis, MS, type 1 diabetes and asthma. In each case, …
Epidemiological studies suggest that autoimmune diseases, such as multiple sclerosis (MS), are less frequent in individuals wh …
GAS6 signaling tempers Th17 development in patients with multiple sclerosis and helminth infection.
Ortiz Wilczyñski JM, Olexen CM, Errasti AE, Schattner M, Rothlin CV, Correale J, Carrera Silva EA. Ortiz Wilczyñski JM, et al. PLoS Pathog. 2020 Dec 21;16(12):e1009176. doi: 10.1371/journal.ppat.1009176. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33347509 Free PMC article.
Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response plays a critical role. Although the mechanisms remain poorly defined, helminth infections are known to modulate the severity and progre
Multiple sclerosis (MS) is a highly disabling neurodegenerative autoimmune condition in which an unbalanced immune response pl
Novel Therapeutics for Multiple Sclerosis Designed by Parasitic Worms.
Dixit A, Tanaka A, Greer JM, Donnelly S. Dixit A, et al. Int J Mol Sci. 2017 Oct 13;18(10):2141. doi: 10.3390/ijms18102141. Int J Mol Sci. 2017. PMID: 29027962 Free PMC article. Review.
The evolutionary response to endemic infections with parasitic worms (helminth) was the development of a distinct regulatory immune profile arising from the need to encapsulate the helminths while simultaneously repairing tissue damage. According to the old friend's …
The evolutionary response to endemic infections with parasitic worms (helminth) was the development of a distinct regulatory immune p …
160 results