Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
1959 1
1960 1
1961 2
1962 1
1963 7
1964 4
1965 8
1966 7
1967 6
1968 6
1969 11
1970 4
1971 6
1972 3
1973 12
1974 5
1975 29
1976 33
1977 23
1978 29
1979 29
1980 38
1981 32
1982 38
1983 41
1984 51
1985 70
1986 56
1987 51
1988 52
1989 81
1990 55
1991 63
1992 59
1993 53
1994 52
1995 38
1996 34
1997 32
1998 42
1999 25
2000 46
2001 46
2002 65
2003 68
2004 92
2005 85
2006 117
2007 115
2008 120
2009 116
2010 114
2011 133
2012 152
2013 134
2014 145
2015 167
2016 144
2017 136
2018 152
2019 158
2020 172
2021 165
2022 170
2023 179
2024 147
2025 153
2026 112

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

4,260 results

Results by year

Filters applied: . Clear all
Page 1
Multivesicular body morphogenesis.
Hanson PI, Cashikar A. Hanson PI, et al. Annu Rev Cell Dev Biol. 2012;28:337-62. doi: 10.1146/annurev-cellbio-092910-154152. Epub 2012 Jul 20. Annu Rev Cell Dev Biol. 2012. PMID: 22831642 Review.
Multivesicular bodies (MVBs) are unique organelles in the endocytic pathway that contain vesicles in their lumen. ...
Multivesicular bodies (MVBs) are unique organelles in the endocytic pathway that contain vesicles in their lumen. ...
A multivesicular body-like organelle mediates stimulus-regulated trafficking of olfactory ciliary transduction proteins.
Maurya DK, Berghard A, Bohm S. Maurya DK, et al. Nat Commun. 2022 Nov 12;13(1):6889. doi: 10.1038/s41467-022-34604-y. Nat Commun. 2022. PMID: 36371422 Free PMC article.
By lectin/immunofluorescence staining and in vivo correlative light-electron microscopy (CLEM), we identify a retinitis pigmentosa-2 (RP2), ESCRT-0 and synaptophysin-containing multivesicular organelle that is not part of generic recycling/degradative/exosome pathways. ...
By lectin/immunofluorescence staining and in vivo correlative light-electron microscopy (CLEM), we identify a retinitis pigmentosa-2 (RP2), …
The ESCRT pathway.
Henne WM, Buchkovich NJ, Emr SD. Henne WM, et al. Dev Cell. 2011 Jul 19;21(1):77-91. doi: 10.1016/j.devcel.2011.05.015. Dev Cell. 2011. PMID: 21763610 Free article. Review.
Multivesicular bodies (MVBs) deliver cargo destined for degradation to the vacuole or lysosome. ...
Multivesicular bodies (MVBs) deliver cargo destined for degradation to the vacuole or lysosome. ...
The ins-and-outs of exosome biogenesis, secretion, and internalization.
Arya SB, Collie SP, Parent CA. Arya SB, et al. Trends Cell Biol. 2024 Feb;34(2):90-108. doi: 10.1016/j.tcb.2023.06.006. Epub 2023 Jul 26. Trends Cell Biol. 2024. PMID: 37507251 Free PMC article. Review.
Exosomes are specialized cargo delivery vesicles secreted from cells by fusion of multivesicular bodies (MVBs) with the plasma membrane (PM). While the function of exosomes during physiological and pathological events has been extensively reported, there remains a l …
Exosomes are specialized cargo delivery vesicles secreted from cells by fusion of multivesicular bodies (MVBs) with the plasma …
Current knowledge on exosome biogenesis and release.
Hessvik NP, Llorente A. Hessvik NP, et al. Cell Mol Life Sci. 2018 Jan;75(2):193-208. doi: 10.1007/s00018-017-2595-9. Epub 2017 Jul 21. Cell Mol Life Sci. 2018. PMID: 28733901 Free PMC article. Review.
Exosomes are nanosized membrane vesicles released by fusion of an organelle of the endocytic pathway, the multivesicular body, with the plasma membrane. This process was discovered more than 30 years ago, and during these years, exosomes have gone from being conside …
Exosomes are nanosized membrane vesicles released by fusion of an organelle of the endocytic pathway, the multivesicular body, …
Multivesicular body and exosome pathway responses to acute exercise.
Garner RT, Solfest JS, Nie Y, Kuang S, Stout J, Gavin TP. Garner RT, et al. Exp Physiol. 2020 Mar;105(3):511-521. doi: 10.1113/EP088017. Epub 2020 Jan 30. Exp Physiol. 2020. PMID: 31917487 Free article.
A greater understanding of the processing of multivesicular bodies in response to acute exercise may lead to novel treatments focused on intercellular communication pathways. ...Exercise-induced regulation of skeletal muscle multivesicular body (MVB) b …
A greater understanding of the processing of multivesicular bodies in response to acute exercise may lead to novel treatments …
Exosomes and Ectosomes in Intercellular Communication.
Meldolesi J. Meldolesi J. Curr Biol. 2018 Apr 23;28(8):R435-R444. doi: 10.1016/j.cub.2018.01.059. Curr Biol. 2018. PMID: 29689228 Free article. Review.
A fraction of endocytic cisternae filled with vesicles - multivesicular bodies - are later destined to undergo regulated exocytosis, leading to the extracellular release of exosomes. ...
A fraction of endocytic cisternae filled with vesicles - multivesicular bodies - are later destined to undergo regulated exocy …
Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.
Zhao GN, Zhang P, Gong J, Zhang XJ, Wang PX, Yin M, Jiang Z, Shen LJ, Ji YX, Tong J, Wang Y, Wei QF, Wang Y, Zhu XY, Zhang X, Fang J, Xie Q, She ZG, Wang Z, Huang Z, Li H. Zhao GN, et al. Nat Med. 2017 Jun;23(6):742-752. doi: 10.1038/nm.4334. Epub 2017 May 8. Nat Med. 2017. PMID: 28481357
Here we report that transmembrane BAX inhibitor motif-containing 1 (TMBIM1) is an effective suppressor of steatohepatitis and a previously unknown regulator of the multivesicular body (MVB)-lysosomal pathway. Tmbim1 expression in hepatocytes substantially inhibited …
Here we report that transmembrane BAX inhibitor motif-containing 1 (TMBIM1) is an effective suppressor of steatohepatitis and a previously u …
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis.
Lee YJ, Shin KJ, Jang HJ, Ryu JS, Lee CY, Yoon JH, Seo JK, Park S, Lee S, Je AR, Huh YH, Kong SY, Kwon T, Suh PG, Chae YC. Lee YJ, et al. Dev Cell. 2023 Feb 27;58(4):320-334.e8. doi: 10.1016/j.devcel.2023.01.006. Epub 2023 Feb 16. Dev Cell. 2023. PMID: 36800996 Free article.
GPR143 interacts with HRS (an ESCRT-0 Subunit) and promotes its association to cargo proteins, such as EGFR, which subsequently enables selective protein sorting into intraluminal vesicles (ILVs) in multivesicular bodies (MVBs). GPR143 is elevated in multiple cancer …
GPR143 interacts with HRS (an ESCRT-0 Subunit) and promotes its association to cargo proteins, such as EGFR, which subsequently enables sele …
Hemifusomes and interacting proteolipid nanodroplets mediate multi-vesicular body formation.
Tavakoli A, Hu S, Ebrahim S, Kachar B. Tavakoli A, et al. Nat Commun. 2025 May 17;16(1):4609. doi: 10.1038/s41467-025-59887-9. Nat Commun. 2025. PMID: 40382390 Free PMC article.
These findings provide direct in situ evidence of long-lived hemifused vesicle complexes and introduce an ESCRT-independent model for multivesicular body (MVB) formation....
These findings provide direct in situ evidence of long-lived hemifused vesicle complexes and introduce an ESCRT-independent model for mul …
4,260 results