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Page 1
Key Pathophysiological Role of Skeletal Muscle Disturbance in Post COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Accumulated Evidence.
Scheibenbogen C, Wirth KJ. Scheibenbogen C, et al. J Cachexia Sarcopenia Muscle. 2025 Feb;16(1):e13669. doi: 10.1002/jcsm.13669. J Cachexia Sarcopenia Muscle. 2025. PMID: 39727052 Free PMC article. Review.
BACKGROUND: Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In a 2021 review article on the pathophysiology of ME/CFS, we postulated that hy …
BACKGROUND: Recent studies provide strong evidence for a key role of skeletal muscle pathophysiology in myalgic encephalomyelitis …
Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Syed AM, Karius AK, Ma J, Wang PY, Hwang PM. Syed AM, et al. Physiology (Bethesda). 2025 Jul 1;40(4):0. doi: 10.1152/physiol.00056.2024. Epub 2025 Feb 17. Physiology (Bethesda). 2025. PMID: 39960432 Free PMC article. Review.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disorder of unclear etiology that affects many individuals worldwide. One of its hallmark symptoms is prolonged fatigue following exertion, a featur …
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disorder of unc …
Mitochondria: It is all about energy.
Casanova A, Wevers A, Navarro-Ledesma S, Pruimboom L. Casanova A, et al. Front Physiol. 2023 Apr 25;14:1114231. doi: 10.3389/fphys.2023.1114231. eCollection 2023. Front Physiol. 2023. PMID: 37179826 Free PMC article. Review.
In this regard, diseases such as cancer, Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS), chronic fatigue syndrome (CFS), and chronic pain are discussed. This review focuses on understanding the mitochondrial mechanisms of action that all …
In this regard, diseases such as cancer, Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS), chronic fatigue syn …
Mitochondrial Dysfunction and Coenzyme Q10 Supplementation in Post-Viral Fatigue Syndrome: An Overview.
Mantle D, Hargreaves IP, Domingo JC, Castro-Marrero J. Mantle D, et al. Int J Mol Sci. 2024 Jan 1;25(1):574. doi: 10.3390/ijms25010574. Int J Mol Sci. 2024. PMID: 38203745 Free PMC article. Review.
Post-viral fatigue syndrome (PVFS) encompasses a wide range of complex neuroimmune disorders of unknown causes characterised by disabling post-exertional fatigue, myalgia and joint pain, cognitive impairments, unrefreshing sleep, autonomic dysfunction, and ne …
Post-viral fatigue syndrome (PVFS) encompasses a wide range of complex neuroimmune disorders of unknown causes characterised b …
Effect of Dietary Coenzyme Q10 Plus NADH Supplementation on Fatigue Perception and Health-Related Quality of Life in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.
Castro-Marrero J, Segundo MJ, Lacasa M, Martinez-Martinez A, Sentañes RS, Alegre-Martin J. Castro-Marrero J, et al. Nutrients. 2021 Jul 30;13(8):2658. doi: 10.3390/nu13082658. Nutrients. 2021. PMID: 34444817 Free PMC article. Clinical Trial.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multisystem, and profoundly debilitating neuroimmune disease, probably of post-viral multifactorial etiology. ...Overall, these findings support the use of CoQ10 plus NADH …
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, multisystem, and profoundly deb …
Mitochondria as the Essence of Yang Qi in the Human Body.
Luo J, Shen S, Xia J, Wang J, Gu Z. Luo J, et al. Phenomics. 2022 Jun 16;2(5):336-348. doi: 10.1007/s43657-022-00060-3. eCollection 2022 Oct. Phenomics. 2022. PMID: 36939762 Free PMC article. Review.
This article discusses the similarities in various aspects between mitochondria and Yang Qi, including body temperature, aging, newborns, circadian rhythm, immunity, and meridian. ...Here, we further explain diseases induced by Yang Qi deficiency, such as cancer, chroni …
This article discusses the similarities in various aspects between mitochondria and Yang Qi, including body temperature, aging, newbo …
Role of mitochondria, oxidative stress and the response to antioxidants in myalgic encephalomyelitis/chronic fatigue syndrome: A possible approach to SARS-CoV-2 'long-haulers'?
Wood E, Hall KH, Tate W. Wood E, et al. Chronic Dis Transl Med. 2021 Mar;7(1):14-26. doi: 10.1016/j.cdtm.2020.11.002. Epub 2020 Nov 21. Chronic Dis Transl Med. 2021. PMID: 33251031 Free PMC article. Review.
A significant number of SARS-CoV-2 (COVID-19) pandemic patients have developed chronic symptoms lasting weeks or months which are very similar to those described for myalgic encephalomyelitis/chronic fatigue syndrome. ...It describes what …
A significant number of SARS-CoV-2 (COVID-19) pandemic patients have developed chronic symptoms lasting weeks or months which are ver …
Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome.
Paul BD, Lemle MD, Komaroff AL, Snyder SH. Paul BD, et al. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2024358118. doi: 10.1073/pnas.2024358118. Proc Natl Acad Sci U S A. 2021. PMID: 34400495 Free PMC article. Review.
Although most patients recover from acute COVID-19, some experience postacute sequelae of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of PASC is a syndrome called "long COVID-19," reminiscent of myalgic encephalomyelitis …
Although most patients recover from acute COVID-19, some experience postacute sequelae of severe acute respiratory syndrome coronavir …
WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome.
Wang PY, Ma J, Kim YC, Son AY, Syed AM, Liu C, Mori MP, Huffstutler RD, Stolinski JL, Talagala SL, Kang JG, Walitt BT, Nath A, Hwang PM. Wang PY, et al. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302738120. doi: 10.1073/pnas.2302738120. Epub 2023 Aug 14. Proc Natl Acad Sci U S A. 2023. PMID: 37579159 Free PMC article.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by various disabling symptoms including exercise intolerance and is diagnosed in the absence of a specific cause, making its clinical management challenging. ...Increas …
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by various disabling symptom …
Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches.
Molnar T, Lehoczki A, Fekete M, Varnai R, Zavori L, Erdo-Bonyar S, Simon D, Berki T, Csecsei P, Ezer E. Molnar T, et al. Geroscience. 2024 Oct;46(5):5267-5286. doi: 10.1007/s11357-024-01165-5. Epub 2024 Apr 26. Geroscience. 2024. PMID: 38668888 Free PMC article. Review.
Among the myriad of symptoms reported by long COVID sufferers, chronic fatigue, cognitive disturbances, and exercise intolerance are predominant, suggesting systemic alterations beyond the initial viral pathology. ...
Among the myriad of symptoms reported by long COVID sufferers, chronic fatigue, cognitive disturbances, and exercise intoleran …
193 results