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Year Number of Results
2010 2
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2015 29
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2017 103
2018 189
2019 271
2020 396
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2023 459
2024 417
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3,089 results

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Page 1
The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells.
Liu NN, Yi CX, Wei LQ, Zhou JA, Jiang T, Hu CC, Wang L, Wang YY, Zou Y, Zhao YK, Zhang LL, Nie YT, Zhu YJ, Yi XY, Zeng LB, Li JQ, Huang XT, Ji HB, Kozlakidis Z, Zhong L, Heeschen C, Zheng XQ, Chen C, Zhang P, Wang H. Liu NN, et al. Cancer Cell. 2023 Nov 13;41(11):1927-1944.e9. doi: 10.1016/j.ccell.2023.08.012. Epub 2023 Sep 21. Cancer Cell. 2023. PMID: 37738973 Free article.
Although polymorphic microbiomes have emerged as hallmarks of cancer, far less is known about the role of the intratumor mycobiome as living microorganisms in cancer progression. Here, using fungi-enriched DNA extraction and deep shotgun metagenomic sequencing, we have ide …
Although polymorphic microbiomes have emerged as hallmarks of cancer, far less is known about the role of the intratumor mycobiome as …
The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly.
Zhang F, Aschenbrenner D, Yoo JY, Zuo T. Zhang F, et al. Lancet Microbe. 2022 Dec;3(12):e969-e983. doi: 10.1016/S2666-5247(22)00203-8. Epub 2022 Sep 28. Lancet Microbe. 2022. PMID: 36182668 Free article. Review.
Over the past decade, accumulating studies have characterised the gut mycobiome in health and several pathological conditions. We review the compositional and functional diversity of the gut mycobiome in healthy populations from birth to adulthood. ...Finally, we di …
Over the past decade, accumulating studies have characterised the gut mycobiome in health and several pathological conditions. We rev …
Mycobiome and Mycobiome-Associated Diseases.
Hagihara M, Kato H, Shibata Y, Umemura T, Ariyoshi T, Hirai J, Asai N, Mori N, Mikamo H. Hagihara M, et al. Med Mycol J. 2023;64(3):55-62. doi: 10.3314/mmj.23-002. Med Mycol J. 2023. PMID: 37648499 Free article. Review.
However, the utilization of a novel metagenomic methodology will enable the identification of well-characterized mycobiomes in several parts of the human body and broaden our knowledge of their contribution to human health and disease. In this article, we review the role o …
However, the utilization of a novel metagenomic methodology will enable the identification of well-characterized mycobiomes in severa …
A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors.
Dohlman AB, Klug J, Mesko M, Gao IH, Lipkin SM, Shen X, Iliev ID. Dohlman AB, et al. Cell. 2022 Sep 29;185(20):3807-3822.e12. doi: 10.1016/j.cell.2022.09.015. Cell. 2022. PMID: 36179671 Free PMC article.
Pan-cancer analysis of multiple body sites revealed tumor-associated mycobiomes at up to 1 fungal cell per 10(4) tumor cells. In lung cancer, Blastomyces was associated with tumor tissues. ...
Pan-cancer analysis of multiple body sites revealed tumor-associated mycobiomes at up to 1 fungal cell per 10(4) tumor cells. In lung …
The gut mycobiome of the Human Microbiome Project healthy cohort.
Nash AK, Auchtung TA, Wong MC, Smith DP, Gesell JR, Ross MC, Stewart CJ, Metcalf GA, Muzny DM, Gibbs RA, Ajami NJ, Petrosino JF. Nash AK, et al. Microbiome. 2017 Nov 25;5(1):153. doi: 10.1186/s40168-017-0373-4. Microbiome. 2017. PMID: 29178920 Free PMC article.
To contribute to existing knowledge of the human mycobiome, we investigated the gut mycobiome of the Human Microbiome Project (HMP) cohort by sequencing the Internal Transcribed Spacer 2 (ITS2) region as well as the 18S rRNA gene. ...ITS2 sequencing data provided gr …
To contribute to existing knowledge of the human mycobiome, we investigated the gut mycobiome of the Human Microbiome Project …
Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.
Alam A, Levanduski E, Denz P, Villavicencio HS, Bhatta M, Alhorebi L, Zhang Y, Gomez EC, Morreale B, Senchanthisai S, Li J, Turowski SG, Sexton S, Sait SJ, Singh PK, Wang J, Maitra A, Kalinski P, DePinho RA, Wang H, Liao W, Abrams SI, Segal BH, Dey P. Alam A, et al. Cancer Cell. 2022 Feb 14;40(2):153-167.e11. doi: 10.1016/j.ccell.2022.01.003. Epub 2022 Feb 3. Cancer Cell. 2022. PMID: 35120601 Free PMC article.
Unexpectedly, IL-33 secretion is dependent on the intratumoral fungal mycobiome. Genetic deletion of IL-33 or anti-fungal treatment decreases T(H)2 and ILC2 infiltration and increases survival. ...These data expand our knowledge of the mechanisms driving PDAC tumor progres …
Unexpectedly, IL-33 secretion is dependent on the intratumoral fungal mycobiome. Genetic deletion of IL-33 or anti-fungal treatment d …
The fecal mycobiome in non-alcoholic fatty liver disease.
Demir M, Lang S, Hartmann P, Duan Y, Martin A, Miyamoto Y, Bondareva M, Zhang X, Wang Y, Kasper P, Bang C, Roderburg C, Tacke F, Steffen HM, Goeser T, Kruglov A, Eckmann L, Stärkel P, Fouts DE, Schnabl B. Demir M, et al. J Hepatol. 2022 Apr;76(4):788-799. doi: 10.1016/j.jhep.2021.11.029. Epub 2021 Dec 10. J Hepatol. 2022. PMID: 34896404 Free PMC article.
RESULTS: The presence of non-obese NASH or F2-F4 fibrosis was associated with a distinct fecal mycobiome signature. Changes were characterized by an increased log-ratio for Mucor sp./Saccharomyces cerevisiae (S. cerevisiae) in patients with NASH and F2-F4 fibrosis. ...CONC …
RESULTS: The presence of non-obese NASH or F2-F4 fibrosis was associated with a distinct fecal mycobiome signature. Changes were char …
Gut mycobiome in metabolic diseases: Mechanisms and clinical implication.
Zhou X, Zhang X, Yu J. Zhou X, et al. Biomed J. 2024 Jun;47(3):100625. doi: 10.1016/j.bj.2023.100625. Epub 2023 Jun 25. Biomed J. 2024. PMID: 37364760 Free PMC article. Review.
Emerging evidence suggests that gut dysbiosis may influence the development of metabolic diseases, in which gut fungal microbiome (mycobiome) is actively involved. In this review, we summarize the studies exploring the composition changes of gut mycobiome in metabol …
Emerging evidence suggests that gut dysbiosis may influence the development of metabolic diseases, in which gut fungal microbiome (mycobi …
The mycobiome: interactions with host and implications in diseases.
Fan Y, Wu L, Zhai B. Fan Y, et al. Curr Opin Microbiol. 2023 Oct;75:102361. doi: 10.1016/j.mib.2023.102361. Epub 2023 Jul 30. Curr Opin Microbiol. 2023. PMID: 37527562 Free article. Review.
Here, we review the recent research progresses in the human mycobiome at different body sites, including the gastrointestinal (GI) tract, the respiratory tract, the urogenital tract, the oral cavity, the skin surface, and the tumor tissues. Researchers have made extensive …
Here, we review the recent research progresses in the human mycobiome at different body sites, including the gastrointestinal (GI) tr …
The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL.
Aykut B, Pushalkar S, Chen R, Li Q, Abengozar R, Kim JI, Shadaloey SA, Wu D, Preiss P, Verma N, Guo Y, Saxena A, Vardhan M, Diskin B, Wang W, Leinwand J, Kurz E, Kochen Rossi JA, Hundeyin M, Zambrinis C, Li X, Saxena D, Miller G. Aykut B, et al. Nature. 2019 Oct;574(7777):264-267. doi: 10.1038/s41586-019-1608-2. Epub 2019 Oct 2. Nature. 2019. PMID: 31578522 Free PMC article.
Bacterial dysbiosis accompanies carcinogenesis in malignancies such as colon and liver cancer, and has recently been implicated in the pathogenesis of pancreatic ductal adenocarcinoma (PDA)(1). However, the mycobiome has not been clearly implicated in tumorigenesis. Here w …
Bacterial dysbiosis accompanies carcinogenesis in malignancies such as colon and liver cancer, and has recently been implicated in the patho …
3,089 results