Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.
Science. 2017 Sep 15;357(6356):1156-1160. doi: 10.1126/science.aah5043.
Science. 2017.
PMID: 28912244
Free PMC article.
Growing evidence suggests that microbes can influence the efficacy of cancer therapies. By studying colon cancer models, we found that bacteria can metabolize the chemotherapeutic drug gemcitabine (2',2'-difluorodeoxycytidine) into its inactive form, 2',2'-difluorod …
Growing evidence suggests that microbes can influence the efficacy of cancer therapies. By studying colon cancer models, we fo …