Precision therapeutic targets for COVID-19.
Krumm ZA, Lloyd GM, Francis CP, Nasif LH, Mitchell DA, Golde TE, Giasson BI, Xia Y.
Krumm ZA, et al.
Virol J. 2021 Mar 29;18(1):66. doi: 10.1186/s12985-021-01526-y.
Virol J. 2021.
PMID: 33781287
Free PMC article.
Review.
We will assess the advantages and limitations of drugs that precisely target evolutionarily well-conserved domains, which are less likely to mutate, and therefore less likely to escape the effects of these drugs. We propose that a multi-drug cocktail targeting precise prot …
We will assess the advantages and limitations of drugs that precisely target evolutionarily well-conserved domains, which are less likely to …