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61 results

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Page 1
Nabiximols in Chronic Neuropathic Pain: A Meta-Analysis of Randomized Placebo-Controlled Trials.
Dykukha I, Malessa R, Essner U, Überall MA. Dykukha I, et al. Pain Med. 2021 Apr 20;22(4):861-874. doi: 10.1093/pm/pnab050. Pain Med. 2021. PMID: 33561282
OBJECTIVE: Pooled analysis of nabiximols and placebo in randomized controlled studies (RCTs) of chronic neuropathic pain. ...METHODS: A systematic literature search was conducted to identify double-blind placebo-controlled RCTs of nabiximols for chr …
OBJECTIVE: Pooled analysis of nabiximols and placebo in randomized controlled studies (RCTs) of chronic neuropathic pain …
A Review of Scientific Evidence for THC:CBD Oromucosal Spray (Nabiximols) in the Management of Chronic Pain.
Überall MA. Überall MA. J Pain Res. 2020 Feb 14;13:399-410. doi: 10.2147/JPR.S240011. eCollection 2020. J Pain Res. 2020. PMID: 32104061 Free PMC article. Review.
Resource utilization associated with chronic pain represents an enormous burden for healthcare systems. Although analgesia based on the World Health Organization's pain ladder continues to be the mainstay of chronic pain management, aside from …
Resource utilization associated with chronic pain represents an enormous burden for healthcare systems. Although analgesia bas …
Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications.
Bilbao A, Spanagel R. Bilbao A, et al. BMC Med. 2022 Aug 19;20(1):259. doi: 10.1186/s12916-022-02459-1. BMC Med. 2022. PMID: 35982439 Free PMC article.
METHODS: We systematically reviewed (registered at PROSPERO: CRD42021229932) eight databases for randomized controlled trials (RCTs) of dronabinol, nabilone, cannabidiol and nabiximols for chronic pain, spasticity, nausea /vomiting, appetite, ALS, irritable b …
METHODS: We systematically reviewed (registered at PROSPERO: CRD42021229932) eight databases for randomized controlled trials (RCTs) of dron …
Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis.
Filippini G, Minozzi S, Borrelli F, Cinquini M, Dwan K. Filippini G, et al. Cochrane Database Syst Rev. 2022 May 5;5(5):CD013444. doi: 10.1002/14651858.CD013444.pub2. Cochrane Database Syst Rev. 2022. PMID: 35510826 Free PMC article.
BACKGROUND: Spasticity and chronic neuropathic pain are common and serious symptoms in people with multiple sclerosis (MS). ...We are uncertain about the effect on chronic neurological pain and health-related quality of life. Cannabinoids may increase …
BACKGROUND: Spasticity and chronic neuropathic pain are common and serious symptoms in people with multiple sclerosis (MS). .. …
Practical considerations in medical cannabis administration and dosing.
MacCallum CA, Russo EB. MacCallum CA, et al. Eur J Intern Med. 2018 Mar;49:12-19. doi: 10.1016/j.ejim.2018.01.004. Epub 2018 Jan 4. Eur J Intern Med. 2018. PMID: 29307505 Review.
With the advent of pharmaceutical cannabis-based medicines (Sativex/nabiximols and Epidiolex), and liberalisation of access in certain nations, this ignorance of cannabis pharmacology and therapeutics has become untenable. ...Suggestions are offered on cannabis-drug intera …
With the advent of pharmaceutical cannabis-based medicines (Sativex/nabiximols and Epidiolex), and liberalisation of access in certai …
Cannabinoids in Chronic Pain: Clinical Outcomes, Adverse Effects and Legal Challenges.
Sic A, George C, Gonzalez DF, Tseriotis VS, Knezevic NN. Sic A, et al. Neurol Int. 2025 Sep 5;17(9):141. doi: 10.3390/neurolint17090141. Neurol Int. 2025. PMID: 41002929 Free PMC article. Review.
Cannabinoids have gained increasing attention as potential therapeutic agents in chronic pain management. Their mechanisms of action, mediated through CB1 and CB2 receptors, provide a pharmacological alternative to conventional analgesics. The evidence is strongest …
Cannabinoids have gained increasing attention as potential therapeutic agents in chronic pain management. Their mechanisms of …
Nabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trial.
Portenoy RK, Ganae-Motan ED, Allende S, Yanagihara R, Shaiova L, Weinstein S, McQuade R, Wright S, Fallon MT. Portenoy RK, et al. J Pain. 2012 May;13(5):438-49. doi: 10.1016/j.jpain.2012.01.003. Epub 2012 Apr 5. J Pain. 2012. PMID: 22483680 Free article. Clinical Trial.
Patients with advanced cancer who have pain that responds poorly to opioid therapy pose a clinical challenge. Nabiximols (Nabiximols is the U.S. ...PERSPECTIVE: Nabiximols, a novel cannabinoid formulation, may be a useful add-on analgesic for patients …
Patients with advanced cancer who have pain that responds poorly to opioid therapy pose a clinical challenge. Nabiximols (N …
Use of cannabidiol (CBD) for the treatment of chronic pain.
Urits I, Gress K, Charipova K, Habib K, Lee D, Lee C, Jung JW, Kassem H, Cornett E, Paladini A, Varrassi G, Kaye AD, Viswanath O. Urits I, et al. Best Pract Res Clin Anaesthesiol. 2020 Sep;34(3):463-477. doi: 10.1016/j.bpa.2020.06.004. Epub 2020 Jul 2. Best Pract Res Clin Anaesthesiol. 2020. PMID: 33004159 Review.
Chronic pain can be recurrent or constant pain that lasts for longer than 3 months and can result in disability, suffering, and a physical disturbance. ...The current pharmaceutical products for the treatment of chronic pain are known as nabi …
Chronic pain can be recurrent or constant pain that lasts for longer than 3 months and can result in disability, suffer …
Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain.
Lichtman AH, Lux EA, McQuade R, Rossetti S, Sanchez R, Sun W, Wright S, Kornyeyeva E, Fallon MT. Lichtman AH, et al. J Pain Symptom Manage. 2018 Feb;55(2):179-188.e1. doi: 10.1016/j.jpainsymman.2017.09.001. Epub 2017 Sep 18. J Pain Symptom Manage. 2018. PMID: 28923526 Free article. Clinical Trial.
CONTEXT: Prior Phase 2/3 studies found that cannabinoids might provide adjunctive analgesia in advanced cancer patients with uncontrolled pain. OBJECTIVES: To assess adjunctive nabiximols (Sativex( )), an extract of Cannabis sativa containing two potentially therape …
CONTEXT: Prior Phase 2/3 studies found that cannabinoids might provide adjunctive analgesia in advanced cancer patients with uncontrolled …
Safety of Medical Cannabis in Neuropathic Chronic Pain Management.
Bennici A, Mannucci C, Calapai F, Cardia L, Ammendolia I, Gangemi S, Calapai G, Griscti Soler D. Bennici A, et al. Molecules. 2021 Oct 16;26(20):6257. doi: 10.3390/molecules26206257. Molecules. 2021. PMID: 34684842 Free PMC article. Review.
Products derived from the plant Cannabis sativa are widely appreciated for their analgesic properties and are employed for the treatment of chronic neuropathic pain. Only nabiximols, a product composed of two extracts containing similar percentages of the two …
Products derived from the plant Cannabis sativa are widely appreciated for their analgesic properties and are employed for the treatment of …
61 results