Structural basis for specific flagellin recognition by the NLR protein NAIP5.
Yang X, Yang F, Wang W, Lin G, Hu Z, Han Z, Qi Y, Zhang L, Wang J, Sui SF, Chai J.
Yang X, et al.
Cell Res. 2018 Jan;28(1):35-47. doi: 10.1038/cr.2017.148. Epub 2017 Nov 28.
Cell Res. 2018.
PMID: 29182158
Free PMC article.
Binding to NAIP5 results in a nearly complete burial of the flagellin derivative, thus stabilizing the active conformation of NAIP5. The extreme C-terminal side of the flagellin is anchored to a sterically constrained binding pocket of NAIP5, wh …
Binding to NAIP5 results in a nearly complete burial of the flagellin derivative, thus stabilizing the active conformation of …