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Page 1
Opioids, Opioid Antagonists.
[No authors listed] [No authors listed] 2020 Nov 24. LiverTox®: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2020 Nov 24. LiverTox®: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643200 Free Books & Documents. Review.
The natural ligands for the opiate receptors are the so-called endogenous opioid peptides such as the enkephalins, endorphins and endomorphins. The opioids have a variety of clinical effects, but are predominantly known and used for their profound pain relieving eff …
The natural ligands for the opiate receptors are the so-called endogenous opioid peptides such as the enkephalins, endorphins …
Reported Benefits of Low-Dose Naltrexone Appear to Be Independent of the Endogenous Opioid System Involving Proopiomelanocortin Neurons and beta-Endorphin.
Metz MJ, Daimon CM, Hentges ST. Metz MJ, et al. eNeuro. 2021 Jun 16;8(3):ENEURO.0087-21.2021. doi: 10.1523/ENEURO.0087-21.2021. Print 2021 May-Jun. eNeuro. 2021. PMID: 34031099 Free PMC article.
Naltrexone is an opioid receptor antagonist approved for the treatment of alcohol and opioid use disorders at doses of 50-150 mg/d. Naltrexone has also been prescribed at much lower doses (3-6 mg/d) for the off-label treatment of inflammation and pain. ...
Naltrexone is an opioid receptor antagonist approved for the treatment of alcohol and opioid use disorders at doses of 50-150 mg/d. …
The endogenous opioid system in the medial prefrontal cortex mediates ketamine's antidepressant-like actions.
Jiang C, DiLeone RJ, Pittenger C, Duman RS. Jiang C, et al. Transl Psychiatry. 2024 Feb 12;14(1):90. doi: 10.1038/s41398-024-02796-0. Transl Psychiatry. 2024. PMID: 38346984 Free PMC article.
Recent studies have implicated the endogenous opioid system in the antidepressant actions of ketamine, but the underlying mechanisms remain unclear. ...Ketamine treatment rapidly increases levels of beta-endorphin and the expression of the mu-opioid receptor gene (O …
Recent studies have implicated the endogenous opioid system in the antidepressant actions of ketamine, but the underlying mechanisms …
Opioids and reproduction.
Seeber B, Böttcher B, D'Costa E, Wildt L. Seeber B, et al. Vitam Horm. 2019;111:247-279. doi: 10.1016/bs.vh.2019.07.001. Epub 2019 Jul 26. Vitam Horm. 2019. PMID: 31421703
More recently, endogenous opioids and their receptor have been identified in a variety of reproductive and non-reproductive tissues outside the central nervous system. ...In men, endogenous opioids play a role in sperm production within the testis. Opioid antagonist …
More recently, endogenous opioids and their receptor have been identified in a variety of reproductive and non-reproductive tissues o …
Neuropeptides and alcohol addiction in monkeys.
van Ree JM, Kornet M, Goosen C. van Ree JM, et al. EXS. 1994;71:165-74. doi: 10.1007/978-3-0348-7330-7_17. EXS. 1994. PMID: 8032147 Review.
Desglycinamide (Arg8) vasopressin (DGAVP) attenuates heroin and cocaine intake during initiation of drug self-administration in rats. beta-Endorphin is self-administered in rats and a role of endogenous opioids in cocaine reward has been proposed. ...The effects are …
Desglycinamide (Arg8) vasopressin (DGAVP) attenuates heroin and cocaine intake during initiation of drug self-administration in rats. beta- …
Endogenous opioid systems and alcohol addiction.
Herz A. Herz A. Psychopharmacology (Berl). 1997 Jan;129(2):99-111. doi: 10.1007/s002130050169. Psychopharmacology (Berl). 1997. PMID: 9040115 Review.
Alcohol exerts numerous pharmacological effects through its interaction with various neurotransmitters and neuromodulators. Among the latter, the endogenous opioids play a key role in the rewarding (addictive) properties of ethanol. Three types of opioid receptors (mu, del …
Alcohol exerts numerous pharmacological effects through its interaction with various neurotransmitters and neuromodulators. Among the latter …
Impact of the opioid system on the reproductive axis.
Böttcher B, Seeber B, Leyendecker G, Wildt L. Böttcher B, et al. Fertil Steril. 2017 Aug;108(2):207-213. doi: 10.1016/j.fertnstert.2017.06.009. Epub 2017 Jun 29. Fertil Steril. 2017. PMID: 28669481 Free article. Review.
In hypothalamic amenorrhea, normal cycles can be restored by the administration of opioid antagonists, such as naltrexone. In polycystic ovarian syndrome, endogenous opioids have found to be elevated and may stimulate insulin secretion from the endocrine pancreas. . …
In hypothalamic amenorrhea, normal cycles can be restored by the administration of opioid antagonists, such as naltrexone. In polycys …
Endogenous opioids and excessive alcohol consumption.
Gianoulakis C. Gianoulakis C. J Psychiatry Neurosci. 1993 Jul;18(4):148-56. J Psychiatry Neurosci. 1993. PMID: 7690585 Free PMC article. Review.
Indeed, injections of small amounts of morphine increased ethanol consumption, while the administration of naltrexone decreased ethanol consumption among rats and other experimental animals, in a number of experimental paradigms, suggesting that endogenous opioids m …
Indeed, injections of small amounts of morphine increased ethanol consumption, while the administration of naltrexone decreased ethan …
Voluntary alcohol consumption and plasma beta-endorphin levels in alcohol-preferring rats chronically treated with naltrexone.
Zalewska-Kaszubska J, Gorska D, Dyr W, Czarnecka E. Zalewska-Kaszubska J, et al. Physiol Behav. 2008 Mar 18;93(4-5):1005-10. doi: 10.1016/j.physbeh.2008.01.007. Epub 2008 Jan 16. Physiol Behav. 2008. PMID: 18262210
Our previous studies have shown that repeated treatment with naltrexone, a nonselective opioid antagonist, results in increased plasma beta-endorphin levels. ...A similar increase in plasma beta-endorphin levels was observed in naltrexone-treated rats …
Our previous studies have shown that repeated treatment with naltrexone, a nonselective opioid antagonist, results in increased plasm …
Endogenous Opioids in the Etiology and Treatment of Multiple Sclerosis.
Zagon IS, McLaughlin PJ. Zagon IS, et al. In: Zagon IS, McLaughlin PJ, editors. Multiple Sclerosis: Perspectives in Treatment and Pathogenesis [Internet]. Brisbane (AU): Codon Publications; 2017 Nov 27. Chapter 8. In: Zagon IS, McLaughlin PJ, editors. Multiple Sclerosis: Perspectives in Treatment and Pathogenesis [Internet]. Brisbane (AU): Codon Publications; 2017 Nov 27. Chapter 8. PMID: 29261263 Free Books & Documents. Review.
Endogenous opioids are enkephalins and endorphins that are primarily produced in the brain and have multiple actions throughout the body. ...Enkephalin levels are reduced in animals and humans during MS relapses, and may play a role in etiology. Exogenous therapy wi …
Endogenous opioids are enkephalins and endorphins that are primarily produced in the brain and have multiple actions throughou …
347 results