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TiO(2)-Nanowired Delivery of Chinese Extract of Ginkgo biloba EGb-761 and Bilobalide BN-52021 Enhanced Neuroprotective Effects of Cerebrolysin Following Spinal Cord Injury at Cold Environment.
Wiklund L, Sharma A, Muresanu DF, Zhang Z, Li C, Tian ZR, Buzoianu AD, Lafuente JV, Nozari A, Feng L, Sharma HS. Wiklund L, et al. Adv Neurobiol. 2023;32:353-384. doi: 10.1007/978-3-031-32997-5_9. Adv Neurobiol. 2023. PMID: 37480466 Review.
In this review, TiO(2) nanowired delivery of EGb-761 and BN-52021 with nanowired cerebrolysin is examined in a rat model of spinal cord injury at cold environment. Our results show that spinal cord injury aggravates cord pathology in cold-acclimated rats and nanowir …
In this review, TiO(2) nanowired delivery of EGb-761 and BN-52021 with nanowired cerebrolysin is examined in a rat model of sp …
Nanodelivery of cerebrolysin reduces pathophysiology of Parkinson's disease.
Ozkizilcik A, Sharma A, Lafuente JV, Muresanu DF, Castellani RJ, Nozari A, Tian ZR, Mössler H, Sharma HS. Ozkizilcik A, et al. Prog Brain Res. 2019;245:201-246. doi: 10.1016/bs.pbr.2019.03.014. Epub 2019 Apr 2. Prog Brain Res. 2019. PMID: 30961868 Review.
In addition, superior neuroprotection induced by nanowired delivery of a multimodal drug cerebrolysin in PD is summarized based on our own investigations....
In addition, superior neuroprotection induced by nanowired delivery of a multimodal drug cerebrolysin in PD is summarized base …
Cerebrolysin restores balance between excitatory and inhibitory amino acids in brain following concussive head injury. Superior neuroprotective effects of TiO(2) nanowired drug delivery.
Sharma HS, Muresanu DF, Sahib S, Tian ZR, Lafuente JV, Buzoianu AD, Castellani RJ, Nozari A, Li C, Zhang Z, Wiklund L, Sharma A. Sharma HS, et al. Prog Brain Res. 2021;266:211-267. doi: 10.1016/bs.pbr.2021.06.016. Epub 2021 Oct 6. Prog Brain Res. 2021. PMID: 34689860
CHI was produced in anesthetized rats by dropping a weight of 114.6g over the right exposed parietal skull from a distance of 20cm height (0.224N impact) and blood-brain barrier (BBB), brain edema, neuronal injuries and behavioral dysfunctions were measured 8, 24, 48 and 72h afte …
CHI was produced in anesthetized rats by dropping a weight of 114.6g over the right exposed parietal skull from a distance of 20cm height (0 …
Spinal cord injury induced exacerbation of Alzheimer's disease like pathophysiology is reduced by topical application of nanowired cerebrolysin with monoclonal antibodies to amyloid beta peptide, p-tau and tumor necrosis factor alpha.
Sharma A, Feng L, Muresanu DF, Tian ZR, Lafuente JV, Buzoianu AD, Nozari A, Wiklund L, Sharma HS. Sharma A, et al. Int Rev Neurobiol. 2023;172:3-35. doi: 10.1016/bs.irn.2023.05.011. Epub 2023 Sep 26. Int Rev Neurobiol. 2023. PMID: 37833015
After 48 h of spinal cord injury elevation of amyloid beta peptide, phosphorylated tau (p-tau) and tumor necrosis factor-alpha (TNF-alpha) was seen in T9 and T12 segments of spinal cord in cerebral cortex, hippocampus and brain stem regions associated with microglial activation a …
After 48 h of spinal cord injury elevation of amyloid beta peptide, phosphorylated tau (p-tau) and tumor necrosis factor-alpha (TNF-alpha) w …
Co-Administration of TiO2 Nanowired Mesenchymal Stem Cells with Cerebrolysin Potentiates Neprilysin Level and Reduces Brain Pathology in Alzheimer's Disease.
Sharma HS, Muresanu DF, Lafuente JV, Patnaik R, Tian ZR, Ozkizilcik A, Castellani RJ, Mössler H, Sharma A. Sharma HS, et al. Mol Neurobiol. 2018 Jan;55(1):300-311. doi: 10.1007/s12035-017-0742-9. Mol Neurobiol. 2018. Retraction in: Mol Neurobiol. 2025 Jan;62(1):1319. doi: 10.1007/s12035-024-04677-5. PMID: 28844104 Retracted.
Since mesenchymal stem cells (MSCs) and/or cerebrolysin (CBL, a combination of neurotrophic factors and active peptide fragments) have neuroprotective effects in various CNS disorders, we examined nanowired delivery of MSCs and CBL on NPL content and brain pathology …
Since mesenchymal stem cells (MSCs) and/or cerebrolysin (CBL, a combination of neurotrophic factors and active peptide fragments) hav …