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Naoxintong Retards Atherosclerosis by Inhibiting Foam Cell Formation Through Activating Pparalpha Pathway.
Wang Z, Shi H, Zhao H, Dong Z, Zhao B, Weng X, Liu R, Li X, Hu K, Zou Y, Sun A, Ge J. Wang Z, et al. Curr Mol Med. 2018;18(10):698-710. doi: 10.2174/1566524019666190207143207. Curr Mol Med. 2018. PMID: 30734676 Free PMC article.
BACKGROUNDS: We recently reported that Naoxintong (NXT), a China Food and Drug Administration (FDA)-approved cardiac medicine, could reduce the plaque size, but the underlying mechanism remains elusive now. ...METHOD: THP-1 cells and bone marrow-derived macrophages were in …
BACKGROUNDS: We recently reported that Naoxintong (NXT), a China Food and Drug Administration (FDA)-approved cardiac medicine, could …
The cardioprotective properties and the involved mechanisms of NaoXinTong Capsule.
Han J, Tan H, Duan Y, Chen Y, Zhu Y, Zhao B, Wang Y, Yang X. Han J, et al. Pharmacol Res. 2019 Mar;141:409-417. doi: 10.1016/j.phrs.2019.01.024. Epub 2019 Jan 17. Pharmacol Res. 2019. PMID: 30660824 Review.
NaoXinTong Capsule (NXT), a prescribed traditional Chinese medicine, is made up of 16 natural herbal materials with more than 200 identified bioactive compounds. Multiple protective effects of NXT on cardiovascular diseases including atherosclerosis, coronary artery …
NaoXinTong Capsule (NXT), a prescribed traditional Chinese medicine, is made up of 16 natural herbal materials with more than 200 ide …
The Effect of Naoxintong Capsule in the Treatment of Patients with Cerebral Infarction and Carotid Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Trials.
Liang Q, Cai Y, Chen R, Chen W, Chen L, Xiao Y. Liang Q, et al. Evid Based Complement Alternat Med. 2018 Jul 24;2018:5892306. doi: 10.1155/2018/5892306. eCollection 2018. Evid Based Complement Alternat Med. 2018. PMID: 30140296 Free PMC article.
OBJECTIVE: Naoxintong capsule (NXT) has been widely used to treat patients with cerebral infarction and carotid atherosclerosis. However, it is uncertain whether there is robust evidence on the effects of NXT for cerebral infarction and carotid atherosclerosis …
OBJECTIVE: Naoxintong capsule (NXT) has been widely used to treat patients with cerebral infarction and carotid atherosclerosis …
Effects of Naoxintong on atherosclerosis and inducible nitric oxide synthase expression in atherosclerotic rabbit.
Zhong XN, Wang HH, Lu ZQ, Dai YQ, Huang JH, Qiu W, Shu YQ, Xu W, Cheng C, Hu XQ. Zhong XN, et al. Chin Med J (Engl). 2013 Mar;126(6):1166-70. Chin Med J (Engl). 2013. PMID: 23506599
BACKGROUND: High levels of nitric oxide (NO) produced by inducible NO synthase (iNOS) have been associated with atherosclerosis processes. Naoxintong is a traditional Chinese medicine for treatment of cerebrovascular and cardiovascular disease. ...CONCLUSION: Nao …
BACKGROUND: High levels of nitric oxide (NO) produced by inducible NO synthase (iNOS) have been associated with atherosclerosis proce …
Naoxintong protects against atherosclerosis through lipid-lowering and inhibiting maturation of dendritic cells in LDL receptor knockout mice fed a high-fat diet.
Zhao J, Zhu H, Wang S, Ma X, Liu X, Wang C, Zhao H, Fan S, Jin X, Zhao B, Zhao T, Jia L, Wang K, Zou Y, Hu K, Sun A, Ge J. Zhao J, et al. Curr Pharm Des. 2013;19(33):5891-6. doi: 10.2174/1381612811319330008. Curr Pharm Des. 2013. PMID: 23438960
Here, we tested the hypothesis that the anti-atherosclerosis effects of NXT might be mediated by suppressing maturation of dendritic cells (DCs) in a mice model of atherosclerosis. ...In addition, expressions of splenic DC membrane molecules (CD40, CD86 and CD80) an …
Here, we tested the hypothesis that the anti-atherosclerosis effects of NXT might be mediated by suppressing maturation of dendritic …
NaoXinTong Inhibits the Advanced Atherosclerosis and Enhances the Plaque Stability in Apolipoprotein E Deficient Mice.
Yang X, Sun L, Li Y, Ma C, Yang J, Zhang W, Zhao B, Jia L, Duan Y, Han J, Li X, Chen Y. Yang X, et al. J Cardiovasc Pharmacol. 2016 Mar;67(3):203-11. doi: 10.1097/FJC.0000000000000334. J Cardiovasc Pharmacol. 2016. PMID: 26485209
Buchang NaoXinTong (NXT), a Chinese medicine, has been widely used to treat patients with coronary heart disease in China. ...In addition, NXT increased expression of smooth muscle 22alpha mRNA while inhibiting expression of matrix metalloproteinase-2 and tumor necrosis fa …
Buchang NaoXinTong (NXT), a Chinese medicine, has been widely used to treat patients with coronary heart disease in China. ...In addi …
NaoXinTong Enhances Atorvastatin-induced Plaque Stability While Ameliorating Atorvastatin-induced Hepatic Inflammation.
Yang X, Li Y, Sun L, Liu Y, Ma C, Chen Y, Tan H, Li Q, Li X, Wang Y, Duan Y, Zhao B, Han J. Yang X, et al. J Cardiovasc Pharmacol. 2017 Jan;69(1):55-64. doi: 10.1097/FJC.0000000000000441. J Cardiovasc Pharmacol. 2017. PMID: 27828790
Buchang NaoXinTong (NXT) is a Chinese medicine that has been used for many years for treatment of patients with coronary heart disease (CHD) in China. ...Herein, we report the effects of NXT on atorvastatin-inhibited atherosclerosis and atorvastatin-induced hepatic …
Buchang NaoXinTong (NXT) is a Chinese medicine that has been used for many years for treatment of patients with coronary heart diseas …
Treatment of Danhong Injection Combined with Naoxintong Capsule in Acute Coronary Syndrome Patients Undergoing PCI Operation: Study for a Randomized Controlled and Double-Blind Trial.
Zhao S, Tang Y, Cai H, Liu W, Zhang L, Chen D, Chen B. Zhao S, et al. Evid Based Complement Alternat Med. 2018 Mar 7;2018:8485472. doi: 10.1155/2018/8485472. eCollection 2018. Evid Based Complement Alternat Med. 2018. PMID: 29707035 Free PMC article.
CONCLUSION: ACS patients treated with Danhong injection combined with Naoxintong capsule after PCI demonstrated better improvement with regard to markers associated with atherosclerosis and adverse cardiovascular events, without apparent adverse effects. Thus, Danho …
CONCLUSION: ACS patients treated with Danhong injection combined with Naoxintong capsule after PCI demonstrated better improvement wi …
Treatment with the herbal medicine, naoxintong improves the protective effect of high-density lipoproteins on endothelial function in patients with type 2 diabetes.
Lv P, Tong X, Peng Q, Liu Y, Jin H, Liu R, Sun W, Pan B, Zheng L, Huang Y. Lv P, et al. Mol Med Rep. 2016 Mar;13(3):2007-16. doi: 10.3892/mmr.2016.4792. Epub 2016 Jan 18. Mol Med Rep. 2016. PMID: 26781332 Free PMC article. Clinical Trial.
The protective effect of high-density lipoprotein (HDL) on endothelial function is impaired in patients with type 2 diabetes mellitus (T2DM), which may result in atherosclerotic complications. Naoxintong (NXT) is a compound preparation that includes Radix Astragali, Angeli …
The protective effect of high-density lipoprotein (HDL) on endothelial function is impaired in patients with type 2 diabetes mellitus (T2DM) …
[Effect of Naoxintong Capsule on Vascular Remodeling in Type 2 Diabetic Patients with Subclinical Vascular Disease].
Cheng SH, Wang J, Xu GH, Sun GX, Tao XJ, Yang XC, Zhu YJ, Chen YW. Cheng SH, et al. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 Dec;36(12):1439-1444. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016. PMID: 30650286 Clinical Trial. Chinese.
Objective To observe the effect of Naoxintong Capsule (NC) on carotid artery vas- cular remodeling (VR) in type 2 diabetes mellitus (T2DM) patients with subclinical vascular disease. Methods A total of 180 T2DM patients with subclinical atherosclerosis (AS) were ran …
Objective To observe the effect of Naoxintong Capsule (NC) on carotid artery vas- cular remodeling (VR) in type 2 diabetes mellitus ( …
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