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Page 1
Naoxintong capsule remodels gut microbiota and ameliorates early-stage atherosclerosis in apolipoprotein E-deficient mice.
Wan H, Lu Y, Yang J, Wan H, Yu L, Fang N, He Y, Li C. Wan H, et al. Phytomedicine. 2024 Jul;129:155662. doi: 10.1016/j.phymed.2024.155662. Epub 2024 Apr 27. Phytomedicine. 2024. PMID: 38728917
BACKGROUND: Naoxintong capsule (NXT) is a compound traditional Chinese medicine prescription with demonstrated effect for the treatment of cardiovascular and cerebrovascular diseases including atherosclerosis (AS). ...
BACKGROUND: Naoxintong capsule (NXT) is a compound traditional Chinese medicine prescription with demonstrated effect for the treatme …
Effects of Naoxintong on atherosclerosis and inducible nitric oxide synthase expression in atherosclerotic rabbit.
Zhong XN, Wang HH, Lu ZQ, Dai YQ, Huang JH, Qiu W, Shu YQ, Xu W, Cheng C, Hu XQ. Zhong XN, et al. Chin Med J (Engl). 2013 Mar;126(6):1166-70. Chin Med J (Engl). 2013. PMID: 23506599
BACKGROUND: High levels of nitric oxide (NO) produced by inducible NO synthase (iNOS) have been associated with atherosclerosis processes. Naoxintong is a traditional Chinese medicine for treatment of cerebrovascular and cardiovascular disease. ...CONCLUSION: Nao …
BACKGROUND: High levels of nitric oxide (NO) produced by inducible NO synthase (iNOS) have been associated with atherosclerosis proce …
Naoxintong Retards Atherosclerosis by Inhibiting Foam Cell Formation Through Activating Pparalpha Pathway.
Wang Z, Shi H, Zhao H, Dong Z, Zhao B, Weng X, Liu R, Li X, Hu K, Zou Y, Sun A, Ge J. Wang Z, et al. Curr Mol Med. 2018;18(10):698-710. doi: 10.2174/1566524019666190207143207. Curr Mol Med. 2018. PMID: 30734676 Free PMC article.
BACKGROUNDS: We recently reported that Naoxintong (NXT), a China Food and Drug Administration (FDA)-approved cardiac medicine, could reduce the plaque size, but the underlying mechanism remains elusive now. ...METHOD: THP-1 cells and bone marrow-derived macrophages were in …
BACKGROUNDS: We recently reported that Naoxintong (NXT), a China Food and Drug Administration (FDA)-approved cardiac medicine, could …
Naoxintong capsules for secondary prevention of ischemic stroke: Meta-Analyses of clinical and preclinical evidence.
Wang L, Chen Y, Chang Z, Shen W, Zhao D, Zhang Y, Gong Z, Liu L, Liang X, Zhang Y. Wang L, et al. J Ethnopharmacol. 2026 Jan 10;354:120535. doi: 10.1016/j.jep.2025.120535. Epub 2025 Sep 3. J Ethnopharmacol. 2026. PMID: 40912480 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Naoxintong, a Chinese patent medicine, may serve as an adjunctive therapy for the secondary prevention of ischemic stroke. ...MATERIALS AND METHODS: A search of electronic databases and registries was performed to locate relevant randomized …
ETHNOPHARMACOLOGICAL RELEVANCE: Naoxintong, a Chinese patent medicine, may serve as an adjunctive therapy for the secondary preventio …
The cardioprotective properties and the involved mechanisms of NaoXinTong Capsule.
Han J, Tan H, Duan Y, Chen Y, Zhu Y, Zhao B, Wang Y, Yang X. Han J, et al. Pharmacol Res. 2019 Mar;141:409-417. doi: 10.1016/j.phrs.2019.01.024. Epub 2019 Jan 17. Pharmacol Res. 2019. PMID: 30660824 Review.
NaoXinTong Capsule (NXT), a prescribed traditional Chinese medicine, is made up of 16 natural herbal materials with more than 200 identified bioactive compounds. Multiple protective effects of NXT on cardiovascular diseases including atherosclerosis, coronary artery …
NaoXinTong Capsule (NXT), a prescribed traditional Chinese medicine, is made up of 16 natural herbal materials with more than 200 ide …
NaoXinTong Inhibits the Advanced Atherosclerosis and Enhances the Plaque Stability in Apolipoprotein E Deficient Mice.
Yang X, Sun L, Li Y, Ma C, Yang J, Zhang W, Zhao B, Jia L, Duan Y, Han J, Li X, Chen Y. Yang X, et al. J Cardiovasc Pharmacol. 2016 Mar;67(3):203-11. doi: 10.1097/FJC.0000000000000334. J Cardiovasc Pharmacol. 2016. PMID: 26485209
Buchang NaoXinTong (NXT), a Chinese medicine, has been widely used to treat patients with coronary heart disease in China. ...Our study demonstrates that NXT can reduce advanced atherosclerosis and enhance the plaque stability in apoE(-/-) mice....
Buchang NaoXinTong (NXT), a Chinese medicine, has been widely used to treat patients with coronary heart disease in China. ...Our stu …
Naoxintong protects against atherosclerosis through lipid-lowering and inhibiting maturation of dendritic cells in LDL receptor knockout mice fed a high-fat diet.
Zhao J, Zhu H, Wang S, Ma X, Liu X, Wang C, Zhao H, Fan S, Jin X, Zhao B, Zhao T, Jia L, Wang K, Zou Y, Hu K, Sun A, Ge J. Zhao J, et al. Curr Pharm Des. 2013;19(33):5891-6. doi: 10.2174/1381612811319330008. Curr Pharm Des. 2013. PMID: 23438960
Here, we tested the hypothesis that the anti-atherosclerosis effects of NXT might be mediated by suppressing maturation of dendritic cells (DCs) in a mice model of atherosclerosis. ...In conclusion, NXT protects against atherosclerosis through lipid-lowering …
Here, we tested the hypothesis that the anti-atherosclerosis effects of NXT might be mediated by suppressing maturation of dendritic …
Naoxintong capsule attenuates heart damage after ischemic stroke via Nuclear factor-kappaB / Pyrin domain-containing protein 3 / Caspase-1 signaling.
Zhang J, Li Y, Chang M, Lei Y, Xu H, Zhang Y, Xu J, Zhang J, Tang S. Zhang J, et al. J Ethnopharmacol. 2025 Feb 11;341:119240. doi: 10.1016/j.jep.2024.119240. Epub 2024 Dec 27. J Ethnopharmacol. 2025. PMID: 39733802
Inflammation exerts an essential part of brain-heart communication after IS. Naoxintong capsule (NXT), derived from the classical Traditional Chinese Medicine (TCM) formulation Bu-Yang-Huan-Wu-Tang, are extensively employed in China to manage IS, myocardial infarction (MI) …
Inflammation exerts an essential part of brain-heart communication after IS. Naoxintong capsule (NXT), derived from the classical Tra …
The Effect of Naoxintong Capsule in the Treatment of Patients with Cerebral Infarction and Carotid Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Trials.
Liang Q, Cai Y, Chen R, Chen W, Chen L, Xiao Y. Liang Q, et al. Evid Based Complement Alternat Med. 2018 Jul 24;2018:5892306. doi: 10.1155/2018/5892306. eCollection 2018. Evid Based Complement Alternat Med. 2018. PMID: 30140296 Free PMC article.
OBJECTIVE: Naoxintong capsule (NXT) has been widely used to treat patients with cerebral infarction and carotid atherosclerosis. However, it is uncertain whether there is robust evidence on the effects of NXT for cerebral infarction and carotid atherosclerosis …
OBJECTIVE: Naoxintong capsule (NXT) has been widely used to treat patients with cerebral infarction and carotid atherosclerosis …
Naoxintong capsules modulates tumor necrosis factor--induced endothelial senescence through silent information regulator 1 signaling.
Guo Q, Zhang B, Zhang H, Zhang E, Wu Y. Guo Q, et al. J Tradit Chin Med. 2021 Apr;41(2):212-218. J Tradit Chin Med. 2021. PMID: 33825400
OBJECTIVE: To investigate the protective effects of Naoxintong capsules ( NXT)on tumor necrosis factor-alpha (TNF-alpha) -induced senescence inendothelial cells and its mechanism. ...This highlights the promise of NXT as a therapeutic for atherosclerosis....
OBJECTIVE: To investigate the protective effects of Naoxintong capsules ( NXT)on tumor necrosis factor-alpha (TNF-alpha) -induced sen …
15 results