Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 2
1975 8
1976 4
1977 5
1978 12
1979 7
1980 6
1981 11
1982 14
1983 16
1984 16
1985 20
1986 22
1987 21
1988 19
1989 16
1990 22
1991 16
1992 26
1993 33
1994 27
1995 17
1996 16
1997 11
1998 22
1999 16
2000 13
2001 28
2002 25
2003 27
2004 29
2005 35
2006 33
2007 32
2008 23
2009 27
2010 27
2011 31
2012 26
2013 31
2014 24
2015 28
2016 29
2017 31
2018 22
2019 21
2020 22
2021 19
2022 13
2023 9
2024 12
2025 13
2026 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

972 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Naproxen for the treatment of neoplastic fever: A PRISMA-compliant systematic review and meta-analysis.
Zhang H, Wu Y, Lin Z, Zhong X, Liu T, Huang Z, Yang Y. Zhang H, et al. Medicine (Baltimore). 2019 May;98(22):e15840. doi: 10.1097/MD.0000000000015840. Medicine (Baltimore). 2019. PMID: 31145329 Free PMC article.
BACKGROUND: The effect of naproxen on the treatment of neoplastic fever is still unclear. A systematic review and meta-analysis were performed to investigate the effect of naproxen in the treatment of cancer fever or suspicion. ...Further well-conducted trials are r …
BACKGROUND: The effect of naproxen on the treatment of neoplastic fever is still unclear. A systematic review and meta-analysis were …
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.
Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, Day R, Ferraz MB, Hawkey CJ, Hochberg MC, Kvien TK, Schnitzer TJ; VIGOR Study Group. Bombardier C, et al. N Engl J Med. 2000 Nov 23;343(21):1520-8, 2 p following 1528. doi: 10.1056/NEJM200011233432103. N Engl J Med. 2000. PMID: 11087881 Free article. Clinical Trial.
We assessed whether rofecoxib, a selective inhibitor of cyclooxygenase-2, would be associated with a lower incidence of clinically important upper gastrointestinal events than is the nonselective NSAID naproxen among patients with rheumatoid arthritis. METHODS: We randomly …
We assessed whether rofecoxib, a selective inhibitor of cyclooxygenase-2, would be associated with a lower incidence of clinically important …
Herbal formulation "turmeric extract, black pepper, and ginger" versus Naproxen for chronic knee osteoarthritis: A randomized, double-blind, controlled clinical trial.
Heidari-Beni M, Moravejolahkami AR, Gorgian P, Askari G, Tarrahi MJ, Bahreini-Esfahani N. Heidari-Beni M, et al. Phytother Res. 2020 Aug;34(8):2067-2073. doi: 10.1002/ptr.6671. Epub 2020 Mar 16. Phytother Res. 2020. PMID: 32180294 Clinical Trial.
Individuals were randomly assigned to receive daily turmeric extract, ginger, and black pepper together or Naproxen capsule for 4 weeks. PGE(2) was evaluated by ELISA method. 24-hr recall was also assessed. ...The results of this study indicated that intake of the selected …
Individuals were randomly assigned to receive daily turmeric extract, ginger, and black pepper together or Naproxen capsule for 4 wee …
Naproxen with or without an antiemetic for acute migraine headaches in adults.
Law S, Derry S, Moore RA. Law S, et al. Cochrane Database Syst Rev. 2013 Oct 20;2013(10):CD009455. doi: 10.1002/14651858.CD009455.pub2. Cochrane Database Syst Rev. 2013. PMID: 24142263 Free PMC article.
No studies combined naproxen with an antiemetic. Studies using naproxen 275 mg provided no useable data for analysis.Naproxen (500 mg and 825 mg) was better than placebo for pain-free response and headache relief. ...Analysing only the lower dose of 500 mg of …
No studies combined naproxen with an antiemetic. Studies using naproxen 275 mg provided no useable data for analysis.Naprox
Efficacy of naproxen prophylaxis for the prevention of heterotopic ossification after hip surgery: a meta-analysis.
Ma R, Chen GH, Zhao LJ, Zhai XC. Ma R, et al. J Orthop Surg Res. 2018 Mar 5;13(1):48. doi: 10.1186/s13018-018-0747-8. J Orthop Surg Res. 2018. PMID: 29506541 Free PMC article.
CONCLUSION: Our analysis indicates that naproxen can decrease the occurrence of heterotopic ossification without increasing complications in hip surgery patients. Due to the limited number of studies included, more high-quality RCTs are needed to identify the optimal dose …
CONCLUSION: Our analysis indicates that naproxen can decrease the occurrence of heterotopic ossification without increasing complicat …
Sumatriptan plus naproxen for acute migraine attacks in adults.
Law S, Derry S, Moore RA. Law S, et al. Cochrane Database Syst Rev. 2013 Oct 21;(10):CD008541. doi: 10.1002/14651858.CD008541.pub2. Cochrane Database Syst Rev. 2013. Update in: Cochrane Database Syst Rev. 2016 Apr 20;4:CD008541. doi: 10.1002/14651858.CD008541.pub3. PMID: 24142431 Updated.
MAIN RESULTS: We included 12 studies using sumatriptan 85 mg or 50 mg plus naproxen 500 mg to treat attacks of mild, moderate, or severe pain intensity: 3663 participants received combination treatment, 3682 placebo, 964 sumatriptan, and 982 naproxen. ...Adverse eve …
MAIN RESULTS: We included 12 studies using sumatriptan 85 mg or 50 mg plus naproxen 500 mg to treat attacks of mild, moderate, or sev …
Naproxen chemoprevention induces proliferation of cytotoxic lymphocytes in Lynch Syndrome colorectal mucosa.
Bowen CM, Deng N, Reyes-Uribe L, Parra ER, Rocha P, Solis LM, Wistuba II, Sepeda VO, Vornik L, Perloff M, Szabo E, Umar A, Sinha KM, Brown PH, Vilar E. Bowen CM, et al. Front Immunol. 2023 May 3;14:1162669. doi: 10.3389/fimmu.2023.1162669. eCollection 2023. Front Immunol. 2023. PMID: 37207208 Free PMC article. Clinical Trial.
While intriguing, the precise immune cell types enriched by naproxen remained unanswered. Here, we have utilized cutting-edge technology to elucidate the immune cell types activated by naproxen in mucosal tissue of LS patients. ...These four populations collectively …
While intriguing, the precise immune cell types enriched by naproxen remained unanswered. Here, we have utilized cutting-edge technol …
Safety profile of over-the-counter naproxen sodium.
DeArmond B, Francisco CA, Lin JS, Huang FY, Halladay S, Bartziek RD, Skare KL. DeArmond B, et al. Clin Ther. 1995 Jul-Aug;17(4):587-601; discussion 586. doi: 10.1016/0149-2918(95)80036-0. Clin Ther. 1995. PMID: 8565023
The safety of naproxen sodium for over-the-counter use was evaluated based on 48 randomized, double-blind, placebo-controlled clinical trials that evaluated naproxen/naproxen sodium (NAP) for indications appropriate to, and under, conditions common to, nonpre …
The safety of naproxen sodium for over-the-counter use was evaluated based on 48 randomized, double-blind, placebo-controlled clinica …
Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa.
Reyes-Uribe L, Wu W, Gelincik O, Bommi PV, Francisco-Cruz A, Solis LM, Lynch PM, Lim R, Stoffel EM, Kanth P, Samadder NJ, Mork ME, Taggart MW, Milne GL, Marnett LJ, Vornik L, Liu DD, Revuelta M, Chang K, You YN, Kopelovich L, Wistuba II, Lee JJ, Sei S, Shoemaker RH, Szabo E, Richmond E, Umar A, Perloff M, Brown PH, Lipkin SM, Vilar E. Reyes-Uribe L, et al. Gut. 2021 Mar;70(3):555-566. doi: 10.1136/gutjnl-2020-320946. Epub 2020 Jul 8. Gut. 2021. PMID: 32641470 Free PMC article. Clinical Trial.
Naproxen demonstrated robust chemopreventive activity in a mouse co-clinical trial and gene expression profiles induced by naproxen in humans showed perfect discrimination of mice specimens with LS and PDOs treated with naproxen and control. CONCLUSIONS: N
Naproxen demonstrated robust chemopreventive activity in a mouse co-clinical trial and gene expression profiles induced by naproxe
A randomized controlled trial of add-on naproxen, simvastatin and their combination for the treatment of schizophrenia or schizoaffective disorder.
Weiser M, Levi L, Park J, Nastas I, Matei V, Davidson M, Arad I, Dudkiewicz I, Davis JM. Weiser M, et al. Eur Neuropsychopharmacol. 2023 Aug;73:65-74. doi: 10.1016/j.euroneuro.2023.04.007. Epub 2023 Apr 30. Eur Neuropsychopharmacol. 2023. PMID: 37126871
This large randomized controlled trial examined the effect of naproxen, simvastatin or both on patients with schizophrenia. This was a large multi-center, twelve-week, randomized, double-blind, placebo-controlled, four-arm clinical trial administering naproxen, simv …
This large randomized controlled trial examined the effect of naproxen, simvastatin or both on patients with schizophrenia. This was …
972 results