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2010 1
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38 results

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Page 1
Stability of rotors and focal sources for human atrial fibrillation: focal impulse and rotor mapping (FIRM) of AF sources and fibrillatory conduction.
Swarup V, Baykaner T, Rostamian A, Daubert JP, Hummel J, Krummen DE, Trikha R, Miller JM, Tomassoni GF, Narayan SM. Swarup V, et al. J Cardiovasc Electrophysiol. 2014 Dec;25(12):1284-92. doi: 10.1111/jce.12559. Epub 2014 Nov 11. J Cardiovasc Electrophysiol. 2014. PMID: 25263408
AF was phase mapped (RhythmView, Topera, Menlo Park, CA, USA). AF propagation movies were interpreted by each operator to assess the source stability/dynamics over tens of minutes before ablation. ...Each source lay in stable atrial regions for 4,196 6 …
AF was phase mapped (RhythmView, Topera, Menlo Park, CA, USA). AF propagation movies were interpreted by each operator to asse …
The continuous challenge of AF ablation: From foci to rotational activity.
Narayan SM, Vishwanathan MN, Kowalewski CAB, Baykaner T, Rodrigo M, Zaman JAB, Wang PJ. Narayan SM, et al. Rev Port Cardiol. 2017 Nov;36 Suppl 1(Suppl 1):9-17. doi: 10.1016/j.repc.2017.09.007. Epub 2017 Nov 8. Rev Port Cardiol. 2017. PMID: 29126896 Free PMC article. Review.
Localized sources lie in atrial regions shown mechanistically to sustain AF in optical mapping and clinical studies of human AF, as well as computational and animal studies. ...However, these studies also show that certain mapping methods are less effective f …
Localized sources lie in atrial regions shown mechanistically to sustain AF in optical mapping and clinical studies of human …
Rotors as drivers of atrial fibrillation and targets for ablation.
Schricker AA, Lalani GG, Krummen DE, Narayan SM. Schricker AA, et al. Curr Cardiol Rep. 2014 Aug;16(8):509. doi: 10.1007/s11886-014-0509-0. Curr Cardiol Rep. 2014. PMID: 24950671 Free PMC article. Review.
Atrial fibrillation (AF) is the most common arrhythmia targeted by catheter ablation. Despite significant advances in our understanding of AF, ablation outcomes remain suboptimal, and this is due in large part to an incomplete understanding of the underlying sustain …
Atrial fibrillation (AF) is the most common arrhythmia targeted by catheter ablation. Despite significant advances in our understandi …
Mechanistic targets for the ablation of atrial fibrillation.
Zaman JAB, Baykaner T, Schricker AA, Krummen DE, Narayan SM. Zaman JAB, et al. Glob Cardiol Sci Pract. 2017 Mar 31;2017(1):e201707. doi: 10.21542/gcsp.2017.7. Glob Cardiol Sci Pract. 2017. PMID: 28971106 Free PMC article. Review.
The mechanisms responsible for sustaining atrial fibrillation are a key debate in cardiovascular pathophysiology, and directly influence the approach to therapy including ablation Clinical and basic studies have split AF mechanisms into two basic camps: 'spatially distribu …
The mechanisms responsible for sustaining atrial fibrillation are a key debate in cardiovascular pathophysiology, and directly influence the …
Ablating Atrial Fibrillation: Customizing Lesion Sets Guided by Rotor Mapping.
Zaman JA, Narayan SM. Zaman JA, et al. Methodist Debakey Cardiovasc J. 2015 Apr-Jun;11(2):76-81. doi: 10.14797/mdcj-11-2-76. Methodist Debakey Cardiovasc J. 2015. PMID: 26306123 Free PMC article. Review.
Recent developments in wide-area mapping and signal processing now identify rotors in the vast majority of AF patients that sustain AF and whose elimination improves long-term freedom from AF in multicenter studies. Investigators have now demonstrated rotor a …
Recent developments in wide-area mapping and signal processing now identify rotors in the vast majority of AF patients that sustain …
Direct or coincidental elimination of stable rotors or focal sources may explain successful atrial fibrillation ablation: on-treatment analysis of the CONFIRM trial (Conventional ablation for AF with or without focal impulse and rotor modulation).
Narayan SM, Krummen DE, Clopton P, Shivkumar K, Miller JM. Narayan SM, et al. J Am Coll Cardiol. 2013 Jul 9;62(2):138-147. doi: 10.1016/j.jacc.2013.03.021. Epub 2013 Apr 3. J Am Coll Cardiol. 2013. PMID: 23563126 Free PMC article. Clinical Trial.

Freedom from AF was highest if all sources were ablated, intermediate if some sources were ablated, and lowest if no sources were ablated (p < 0.001). CONCLUSIONS: Elimination of stable AF rotors and focal sources may explain freedom f

…
Freedom from AF was highest if all sources were ablated, intermediate if some sources were ablated, and lowest if no …
The role of rotors in atrial fibrillation.
Krummen DE, Swarup V, Narayan SM. Krummen DE, et al. J Thorac Dis. 2015 Feb;7(2):142-51. doi: 10.3978/j.issn.2072-1439.2014.11.15. J Thorac Dis. 2015. PMID: 25713729 Free PMC article. Review.
Panoramic contact mapping, incorporating phase analysis, repolarization and conduction dynamics, and oscillations in AF rate, overcomes many prior difficulties with mapping AF. This approach provides evidence that the mechanisms sustaining human AF are determ …
Panoramic contact mapping, incorporating phase analysis, repolarization and conduction dynamics, and oscillations in AF rate, overcom …
Comparing phase and electrographic flow mapping for persistent atrial fibrillation.
Swerdlow M, Tamboli M, Alhusseini MI, Moosvi N, Rogers AJ, Leef G, Wang PJ, Rillig A, Brachmann J, Sauer WH, Ruppersberg P, Narayan SM, Baykaner T. Swerdlow M, et al. Pacing Clin Electrophysiol. 2019 May;42(5):499-507. doi: 10.1111/pace.13649. Epub 2019 Mar 24. Pacing Clin Electrophysiol. 2019. PMID: 30882924 Free PMC article.
BACKGROUND: An increasing number of methods are being used to map atrial fibrillation (AF), yet the sensitivity of identifying potential localized AF sources of these novel methods are unclear. ...EGF and phase mapping identified localized sources at …
BACKGROUND: An increasing number of methods are being used to map atrial fibrillation (AF), yet the sensitivity of identifying potent …
Comparison of phase mapping and electrogram-based driver mapping for catheter ablation in atrial fibrillation.
Lin CY, Lin YJ, Narayan SM, Baykaner T, Lo MT, Chung FP, Chen YY, Chang SL, Lo LW, Hu YF, Liao JN, Tuan TC, Chao TF, Te ALD, Kuo L, Vicera JJB, Chang TY, Salim S, Chien KL, Chen SA. Lin CY, et al. Pacing Clin Electrophysiol. 2019 Feb;42(2):216-223. doi: 10.1111/pace.13573. Epub 2018 Dec 27. Pacing Clin Electrophysiol. 2019. PMID: 30536679 Free PMC article.
INTRODUCTION: Adjunctive driver-guided ablation in addition to pulmonary vein isolation has been proposed as a strategy to improve procedural success and outcomes for various populations with atrial fibrillation (AF). First, this study aimed to evaluate the different mappi …
INTRODUCTION: Adjunctive driver-guided ablation in addition to pulmonary vein isolation has been proposed as a strategy to improve procedura …
Stochastic termination of spiral wave dynamics in cardiac tissue.
Rappel WJ, Krummen DE, Baykaner T, Zaman J, Donsky A, Swarup V, Miller JM, Narayan SM. Rappel WJ, et al. Front Netw Physiol. 2022 Jan;2:809532. doi: 10.3389/fnetp.2022.809532. Epub 2022 Jan 26. Front Netw Physiol. 2022. PMID: 36187938 Free PMC article.
In non-homogeneous media, however, heterogeneities can act as anchoring sources that result in sustained spiral wave activity. It is thus unclear how and if AF may terminate following the removal of putative spiral wave sources in patients. ...To validate the …
In non-homogeneous media, however, heterogeneities can act as anchoring sources that result in sustained spiral wave activity. It is …
38 results