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311 results

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Page 1
Nattokinase atherothrombotic prevention study: A randomized controlled trial.
Hodis HN, Mack WJ, Meiselman HJ, Kalra V, Liebman H, Hwang-Levine J, Dustin L, Kono N, Mert M, Wenby RB, Huesca E, Rochanda L, Li Y, Yan M, St John JA, Whitfield L. Hodis HN, et al. Clin Hemorheol Microcirc. 2021;78(4):339-353. doi: 10.3233/CH-211147. Clin Hemorheol Microcirc. 2021. PMID: 33843667 Clinical Trial.
BACKGROUND: Described to be antithrombotic and antihypertensive, nattokinase is consumed for putative cardiovascular benefit. However, no large-scale, long-term cardiovascular study has been conducted with nattokinase supplementation. ...RESULTS: After median 3 year …
BACKGROUND: Described to be antithrombotic and antihypertensive, nattokinase is consumed for putative cardiovascular benefit. However …
Nattokinase Supplementation and Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Li X, Long J, Gao Q, Pan M, Wang J, Yang F, Zhang Y. Li X, et al. Rev Cardiovasc Med. 2023 Aug 15;24(8):234. doi: 10.31083/j.rcm2408234. eCollection 2023 Aug. Rev Cardiovasc Med. 2023. PMID: 39076715 Free PMC article.
BACKGROUND: As a fibrinolytic enzyme from fermented soybean, nattokinase has been shown to be potentially beneficial for cardiovascular health, but current clinical evidences regarding the nattokinase supplementation on cardiovascular risk factors are various. ...No …
BACKGROUND: As a fibrinolytic enzyme from fermented soybean, nattokinase has been shown to be potentially beneficial for cardiovascul …
Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2.
Tanikawa T, Kiba Y, Yu J, Hsu K, Chen S, Ishii A, Yokogawa T, Suzuki R, Inoue Y, Kitamura M. Tanikawa T, et al. Molecules. 2022 Aug 24;27(17):5405. doi: 10.3390/molecules27175405. Molecules. 2022. PMID: 36080170 Free PMC article.
In this study, we examined the effect of nattokinase on the S protein of SARS-CoV-2. When cell lysates transfected with S protein were incubated with nattokinase, the S protein was degraded in a dose- and time-dependent manner. Immunofluorescence analysis showed tha …
In this study, we examined the effect of nattokinase on the S protein of SARS-CoV-2. When cell lysates transfected with S protein wer …
Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases.
Chen H, McGowan EM, Ren N, Lal S, Nassif N, Shad-Kaneez F, Qu X, Lin Y. Chen H, et al. Biomark Insights. 2018 Jul 5;13:1177271918785130. doi: 10.1177/1177271918785130. eCollection 2018. Biomark Insights. 2018. PMID: 30013308 Free PMC article. Review.
Cardiovascular disease (CVD) is the leading cause of death in the world and our approach to the control and management of CVD mortality is limited. Nattokinase (NK), the most active ingredient of natto, possesses a variety of favourable cardiovascular effects and the consu …
Cardiovascular disease (CVD) is the leading cause of death in the world and our approach to the control and management of CVD mortality is l …
Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease.
Weng Y, Yao J, Sparks S, Wang KY. Weng Y, et al. Int J Mol Sci. 2017 Feb 28;18(3):523. doi: 10.3390/ijms18030523. Int J Mol Sci. 2017. PMID: 28264497 Free PMC article. Review.
Natto, a fermented soybean product, has been consumed as a traditional food in Japan for thousands of years. Nattokinase (NK), a potent blood-clot dissolving protein used for the treatment of cardiovascular diseases, is produced by the bacterium Bacillus subtilis during th …
Natto, a fermented soybean product, has been consumed as a traditional food in Japan for thousands of years. Nattokinase (NK), a pote …
Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants.
Chen H, Chen J, Zhang F, Li Y, Wang R, Zheng Q, Zhang X, Zeng J, Xu F, Lin Y. Chen H, et al. Front Cardiovasc Med. 2022 Aug 22;9:964977. doi: 10.3389/fcvm.2022.964977. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36072877 Free PMC article.
Nattokinase (NK), known as a potent fibrinolytic and antithrombotic agent, has been shown to have antiatherosclerotic and lipid-lowering effects. ...
Nattokinase (NK), known as a potent fibrinolytic and antithrombotic agent, has been shown to have antiatherosclerotic and lipid-lower …
Nattokinase as an adjuvant therapeutic strategy for non-communicable diseases: a review of fibrinolytic, antithrombotic, anti-inflammatory, and antioxidant effects.
Granito M, Alvarenga L, Ribeiro M, Carvalhosa P, Andrade T, Mesquita CT, Stockler-Pinto MB, Mafra D, Cardozo LF. Granito M, et al. Expert Rev Cardiovasc Ther. 2024 Oct;22(10):565-574. doi: 10.1080/14779072.2024.2416663. Epub 2024 Oct 15. Expert Rev Cardiovasc Ther. 2024. PMID: 39404094 Review.
INTRODUCTION: Nattokinase (NK) is the primary ingredient of natto, a traditional Asian food made from fermented soybean by Bacillus subtilis natto. ...EXPERT OPINION: Due to the fibrinolytic and antithrombotic activity of nattokinase, and more recently added to the …
INTRODUCTION: Nattokinase (NK) is the primary ingredient of natto, a traditional Asian food made from fermented soybean by Bacillus s …
Microbial nattokinase: from synthesis to potential application.
Sheng Y, Yang J, Wang C, Sun X, Yan L. Sheng Y, et al. Food Funct. 2023 Mar 20;14(6):2568-2585. doi: 10.1039/d2fo03389e. Food Funct. 2023. PMID: 36857725 Review.
Nattokinase (NK) is an alkaline serine protease with strong thrombolytic activity produced by Bacillus spp. or Pseudomonas spp. ...
Nattokinase (NK) is an alkaline serine protease with strong thrombolytic activity produced by Bacillus spp. or Pseudomonas spp. ...
The Effect of Nattokinase-Monascus Supplements on Dyslipidemia: A Four-Month Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Liu X, Zeng X, Mahe J, Guo K, He P, Yang Q, Zhang Z, Li Z, Wang D, Zhang Z, Wang L, Jing L. Liu X, et al. Nutrients. 2023 Sep 30;15(19):4239. doi: 10.3390/nu15194239. Nutrients. 2023. PMID: 37836525 Free PMC article. Clinical Trial.
This study aims to examine the effect of nattokinase monascus supplements (NMSs) on cardiovascular biomarkers and carotid intima-media thickness (CIMT) in patients with dyslipidemia. ...
This study aims to examine the effect of nattokinase monascus supplements (NMSs) on cardiovascular biomarkers and carotid intima-medi …
Biotechnology, Bioengineering and Applications of Bacillus Nattokinase.
Yuan L, Liangqi C, Xiyu T, Jinyao L. Yuan L, et al. Biomolecules. 2022 Jul 13;12(7):980. doi: 10.3390/biom12070980. Biomolecules. 2022. PMID: 35883536 Free PMC article. Review.
In view of the problems of low fermentation yield, insufficient activity and stability of nattokinase, this review discusses the heterologous expression of nattokinase in different microbial hosts and summarizes the protein and genetic engineering progress of nat …
In view of the problems of low fermentation yield, insufficient activity and stability of nattokinase, this review discusses the hete …
311 results